AxonalPlasticityLab
@AxonalLab
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The Axonal Plasticity Lab is located at the Institute of Anatomy and Cell Biology at JKU Linz, Austria.
Joined February 2020
Quite remarkable (understatement of the day!).
Published in @ScienceMagazine: "Direct optical measurement of intramolecular distances with angstrom precision" (Sahl et al.). @mpi_nat @mpi_mr_hd #Optics #Imaging #Microscopy #MINFLUX #Fluorescence
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Fantastic opportunity for candidates serious about top notch cell biology in combination with cutting edge imaging!!.
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RT @StefanHellLabs: PNAS Inaugural Article published:."MINFLUX reveals dynein stepping in live neurons" .by J.M. Schleske et al. Open acces….
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RT @YukiOgawaPhD: My research focuses on the axon initial segment in neurons. I’ll be expanding this work by combining efficient CRISPR gen….
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RT @dav1dcg: A dendrite is a dendrite is a dendrite? Dendritic signal integration beyond the “antenna” model.
link.springer.com
Pflügers Archiv - European Journal of Physiology - Neurons in central nervous systems receive multiple synaptic inputs and transform them into a largely standardized output to their target...
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New publication focusing on one of the coolest cell types ever!.
What do you know about Cajal-Retzius cells? Here we show a novel role of this transient population, known for their contribution in cortical layering.
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RT @adorrego_r: An evolutionarily conserved AnkyrinG-dependent motif clusters axonal K2P K+ channels .
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And another piece of the puzzle . great work @VictorMacarron and @ElisaDEste & team.
Interested in the neuronal cytoskeleton? We introduce Palm1 as a component of the submembrane cytoskeleton. Palm1 is located at the actin-spectrin-adducin junctions and controls the periodic pattern of numerous cytoskeletal protein, thus of the MPS. #MINFLUX, #STED, #Y2H
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I have to ask - will this be streamed?? We would all love to hear it! With and without the AIS!.
London #neuroscience 🧠 community, you really have to register for 𝗣𝗿𝗼𝗳𝗲𝘀𝘀𝗼𝗿 @GrubbLab's inaugural lecture @dev_neuro @KingsIoPPN. It will clearly be a masterclass in puns - and yes, he will also probably show some pretty cool science⤵️.
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FAT CONGRATS MATT !!!.
Wohooo! 🥳🥳.
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Super place for some amazing science, in a great city on top of that! Go check out the Kole group!!.
Vacancy alert: we are looking for a postdoc! If you would like to work on the wiring and physiology of the axon (initial segment) in a highly collaborative and supportive environment, supervised by a fantastic mentor, go apply! Please share and retweet🧠.
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Tumor-neuron networks continue to intrigue me ever since we received out first surgery samples from @Miriam__Ratliff in Mannheim. Nice to see you're still going strong! Cheers from Linz!.
As part of my PhD thesis @wick_wolfgang lab @DKFZ, @uniklinik_hd, @UniHeidelberg, @HdNeurooncology we investigated the cellular and molecular composition of tumor microtube networks in #Glioblastoma (1/6). The manuscript is hot off the press @NatureComms: .
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Thorough study with exciting data by our friends across the big pond at @jenkins_paul lab and @NeuroBender . I love the straight forward approach and your attention to detail! Science as it should be😎Congratulations!!.
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RT @Dev_journal: Cajal-Retzius cells in the postnatal hippocampus. Read this Research Highlight showcasing work from Ingvild Lynneberg Glæ….
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RT @LMPrida: Now published in @BrainStrucFunc !! Our immunohistochemical parcellation of human hippocampal fields DG, CA3, #CA2 & CA1 all a….
link.springer.com
Brain Structure and Function - The primate hippocampus includes the dentate gyrus, cornu ammonis (CA), and subiculum. CA is subdivided into four fields (CA1-CA3, plus CA3h/hilus of the dentate...
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RT @NIN_knaw: Experience shapes chandelier cell function and structure in the visual cortex: This publication was….
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Christmas indeed - a new and very interesting study unraveling more of the dynamics at the AIS. Needless to add - beautiful images! Congratulations @christlet and @Biosdfp !.
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RT @eLife: 20-30% of scientists may be using commercial antibodies that don’t work as advertised in their protein studies, potentially skew….
elifesciences.org
Twenty to thirty percent of scientists may be using ineffective commercial antibodies in their protein studies suggesting that large-scale independent antibody validation is needed.
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So exciting to see this piece of beauty out for real. Congratulations @FreAmeLie and @NoraJamann plus team!.Sodium channel endocytosis drives axon initial segment plasticity | Science Advances
science.org
Rapid activity-dependent sodium channel internalization at the axon initial segment tunes the action potential output.
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