Congratulations to @RNA_Richard for being awarded the Race Against Dementia Fellowship 👏 🔗 Read more about the prestigious 5-year award and Richard's research into synapse resilience and neuroprotective mechanisms in healthy ageing and dementia:

Dr. Katie Long is leading vital research, funded by an MRF award, to learn how pregnant people feel about vaccines during pregnancy. We want your views! Take this short survey:: https://t.co/coR60hUc3r For more information on vaccines in pregnancy visit https://t.co/MSNUbEhfPr

We're #hiring! Looking for an experienced and dynamic Research Strategy Manager... More details in link below Deadline 09 July https://t.co/ymHwYZxrqg

We're #hiring for a new role as Senior EA to our wonderful Director and Managing Director! Deadline 23 June https://t.co/pxS6Hsiwgk

New paper from Julie Jézéquel and the @Rico_lab on role of cadherins in neuronal inhibition out now in @NatureComms! https://t.co/i7bxUZG80a

I am hiring!! Please share in your networks. Deadline to apply: 26th May 2025 https://t.co/TMqNbndgFG

7/10 For PV interneurons, Vgf is the critical gene modulating the plasticity of inhibitory inputs received from other PV interneurons

4/10 Using experimental manipulations, we found that PV interneurons scale the inhibition they receive to maintain stability. When the activity of a PV interneuron increases, it “requests” more inhibitory inputs from other PV+ interneurons, effectively rebalancing its activity

3/10 Neuronal activity operates within a tightly controlled range for the optimal functioning of #brain circuits. When synaptic connectivity and network activity are modified, such as when we are learning, compensatory mechanisms are needed to maintain stability

5/10 How is this achieved? We found that PV interneurons induce the expression of two genes encoding multiple neuropeptides, Scg2 and Vgf, in response to increased activity

2/10 The cortex contains two main classes of neurons: excitatory “go” pyramidal cells and inhibitory “no-go” #interneurons

10/10 Here’s the paper @Nature if you want to dig in https://t.co/HvYAZe9LZc That’s it. Thanks for sharing! @dev_neuro @MRC_CNDD @KingsIoPPN @ERC_Research

9/10 In sum, our findings identify a previously unknown form of interneuron plasticity and strengthen the idea that neuropeptide signalling plays crucial roles in maintaining neural circuit stability. Funded by the magnificents @ERC_Research and @RosetreesT

1/10 Our latest research, led by @MartijnSelten, identifies a mechanism through which Parvalbumin (PV) interneurons regulate their activity in the #cortex. This is the story @Nature https://t.co/HvYAZe9LZc 🧵⬇︎ @dev_neuro @MRC_CNDD @KingsIoPPN @ERC_Research @RosetreesT

We are recruiting! We're looking for a dynamic, experienced Research Strategy Manager to join us. More details and application link:

Only 1 week left to apply for a faculty position at the fantastic @WolfsonSPaRC Are you doing phenomenal research into spinal cord & brain repair, chronic pain or sensory systems? Do you want to join a vibrant, collegiate Centre in the heart of London? If so, then please apply!

Dev Neuro Academy: Pathways to Discovery – a new short film by Asma Bashir – showcases the ethos, experiences, and impact of this flagship widening participation initiative at the Centre for Developmental Neurobiology. Watch here:

Join us today at 1pm for our internal seminar series!

Check out the @LeverhulmeTrust feature on the exciting research by @L_andreae and Karen Page, recipients of their Research Project Grant.🔬 Read more about their innovative work here:

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