
Alexandra Davies
@Alex_Doune
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Lecturer & group leader @FBMH_UoM, @MCF_UoM. Cell biology, proteomics, rare disease, #CureAP4
Manchester, England
Joined November 2015
What a year it's been for the Davies Lab v1.0! Our 1st year in Manchester @MCF_UoM comes to a close. We're wishing congratulations to Jani and Emily for completing their degrees and welcoming Zac to the team. And Juliet just aced her 1st year viva! #dreamteam.🙌🔬🌈🎉
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RT @rarediseaseday: The number of people living with a rare disease is equivalent to the third largest country in the world. 🌎. On #RareDi….
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Paper just out from our lab member @ZacSandy on a cool #massspec method he applied to study ISG15 during his PhD in @C_K_Schmidt Lab:.Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions.
pubmed.ncbi.nlm.nih.gov
Non-covalent protein-protein interactions are one of the most fundamental building blocks in cellular signalling pathways. Despite this, they have been historically hard to identify using conventio...
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RT @Co_Biologists: Are you an early-career researcher working in an area covered by @J_Cell_Sci and would like to attend a #microscopy trai….
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Thanks @TheCoxLab #MQSS2024 organisers and speakers. My lab members (hiding at the back) had an incredible crash course in #massspec #proteomics data analysis! Kudos 🙌.
MaxQuant Summer School 2024 #MQSS2024 in Munich was a great success! Thanks to all participants and speakers! You can now watch selected presentations on our YouTube channel ( . Stay tuned,we're already organizing next year’s one!.#proteomics #TeamMassSpec
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Fab to see this exciting work out on @biorxivpreprint. Congrats 🎉 @MAFesenko, @moore_cell, @clathrin and team. Now, why am I suddenly craving skittles?! 🌈😂.
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Exciting new #HSP #raredisease research from @ReidLab_HSP. Congratulations Eliska and the rest of the team! 👏.
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Wow! This looks incredible! 🔬.
Out at @naturemethods just now!. We present #SN2N, a flagship level unsupervised denoising solution. It’s fully competitive with supervised learning without needing large training-set and clean ground-truth, using 1 noisy frame for training. (1/n)
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RT @MCF_UoM: We are searching for an outstanding researcher to join the @LabBuckley. The successful candidate will use optogenetic, live i….
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Only two days left to apply to join my new lab at the University of Manchester @MCF_UoM @FBMH_UoM!. #PleaseShare #Applynow
My lab @MCF_UoM is #hiring a Research Technician. I'm looking for someone with experience in #iPSC & #microscopy. You will be trained in #proteomics and the project will tackle the mechanisms underlying rare neurological diseases. Apply now! .#pleaseshare.
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My lab @MCF_UoM is #hiring a Research Technician. I'm looking for someone with experience in #iPSC & #microscopy. You will be trained in #proteomics and the project will tackle the mechanisms underlying rare neurological diseases. Apply now! .#pleaseshare.
jobs.manchester.ac.uk
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RT @labs_mann: 1/7 @labs_mann and Georg Wallmann @GeorgWa are proud to announce alphaDIA, our open source, next generation DIA search engin….
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Was a pleasure to collaborate with my former PhD supervisor, Scottie Robinson @TheCIMR, on this fantastic paper, just out in @JCellBiol. 40 years after Scottie discovered the #clathrin adaptor AP-1, she is still revealing surprises about its function!.
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I'm delighted to have received a Springboard award from @acmedsci and excited about where it will spring my lab to! 🪺. Watch this space for a research technician position supporting #iPSC #raredisease modelling and #proteomics!.
We are thrilled to announce that @Alex_Doune has secured the Springboard Award from the @acmedsci!. @FBMH_UoM .
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Thanks to the Wahlig family for bringing us all together to learn about HSP. Another wonderful meeting! #TWS2024 #TreatHSP #raredisease.
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Was an absolute pleasure to host you @ScheffoldM.
Back in Boston after 2 amazing weeks at Manchester learning Proteomics from @Alex_Doune as part of my project @DEF_Lab_HMS. So grateful to Alex for teaching me and to @Boehringer MD Fellowship for funding my stay. Still in awe of the exciting research and the enchanting city.
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RT @PliotasGroup: We have a 3-year @BBSRC postdoc available in Manchester @MCF_UoM @FBMH_UoM @UoMMIB to utilise.#EPR spectroscopy to addres….
jobs.manchester.ac.uk
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RT @MCF_UoM: Message from our new member: @LabBuckley is searching for outstanding researchers to join us as we move to MCF. We use optogen….
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So excited to see this paper out! 🎊 Incredible work from @DEF_Lab_HMS using #protein #mislocalisation phenotypes as a #drugscreen to identify a drug that restores the cellular distribution of ATG9A in AP4-deficient neurons and increases #autophagy flux. So cool! #CureAP4 #neuro.
This week we @BostonChildrens @FMKirbyNeuro report in @NatureComms a cell-based phenotypic high-throughput assay for AP-4-related #hereditaryspasticparaplegia. Screen of ~29K compounds with @Astellas identified BCH-HSP-C01 👉🏽 #raredisease @CureAP4 @CureSPG50 @SpasticParapleg
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