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Alexandra Davies Profile
Alexandra Davies

@Alex_Doune

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Lecturer & group leader @FBMH_UoM, @MCF_UoM. Cell biology, proteomics, rare disease, #CureAP4

Manchester, England
Joined November 2015
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@Alex_Doune
Alexandra Davies
1 year
What a year it's been for the Davies Lab v1.0! Our 1st year in Manchester @MCF_UoM comes to a close. We're wishing congratulations to Jani and Emily for completing their degrees and welcoming Zac to the team. And Juliet just aced her 1st year viva! #dreamteam πŸ™ŒπŸ”¬πŸŒˆπŸŽ‰
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@rarediseaseday
Rare Disease Day
10 months
The number of people living with a rare disease is equivalent to the third largest country in the world. 🌎 On #RareDiseaseDay, we aim to highlight their voices and raise awareness about their experiences. Download our Infographics: https://t.co/lLgsmLrUvN
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@Alex_Doune
Alexandra Davies
10 months
Paper just out from our lab member @ZacSandy on a cool #massspec method he applied to study ISG15 during his PhD in @C_K_Schmidt Lab: Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions.
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pubmed.ncbi.nlm.nih.gov
Non-covalent protein-protein interactions are one of the most fundamental building blocks in cellular signalling pathways. Despite this, they have been historically hard to identify using conventio...
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@Co_Biologists
The Company of Biologists
1 year
Are you an early-career researcher working in an area covered by @J_Cell_Sci and would like to attend a #microscopy training course? The next deadline is 22 November to apply for a Β£1,000 JCS-FocalPlane Training Grant. https://t.co/iKe47HNXHk @focalplane_jcs
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@Alex_Doune
Alexandra Davies
1 year
Thanks @TheCoxLab #MQSS2024 organisers and speakers. My lab members (hiding at the back) had an incredible crash course in #massspec #proteomics data analysis! Kudos πŸ™Œ
@maxquant
MaxQuant
1 year
MaxQuant Summer School 2024 #MQSS2024 in Munich was a great success! Thanks to all participants and speakers! You can now watch selected presentations on our YouTube channel ( https://t.co/Bp7i2ABXbn) . Stay tuned,we're already organizing next year’s one! #proteomics #TeamMassSpec
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@Alex_Doune
Alexandra Davies
1 year
Fab to see this exciting work out on @biorxivpreprint. Congrats πŸŽ‰ @MAFesenko, @moore_cell, @clathrin and team. Now, why am I suddenly craving skittles?! πŸŒˆπŸ˜‚
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@Alex_Doune
Alexandra Davies
1 year
Exciting new #HSP #raredisease research from @ReidLab_HSP. Congratulations Eliska and the rest of the team! πŸ‘
@ReidLab_HSP
Evan Reid
2 years
Our latest thing: Atlastin-1 regulates endosomal tubulation and lysosomal proteolysis in...
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@Alex_Doune
Alexandra Davies
1 year
Wow! This looks incredible! πŸ”¬
@weisong_zhao
Weisong Zhao
1 year
Out at @naturemethods just now! https://t.co/SAiolzlnBy We present #SN2N, a flagship level unsupervised denoising solution. It’s fully competitive with supervised learning without needing large training-set and clean ground-truth, using 1 noisy frame for training. (1/n)
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@MCF_UoM
Division of Molecular and Cellular Function UoM
1 year
We are searching for an outstanding researcher to join the @LabBuckley. The successful candidate will use optogenetic, live imaging and quantitative analysis approaches to understand how mechanics and biochemical signalling shape epithelial organs. https://t.co/hrNqg5ZIni
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@Alex_Doune
Alexandra Davies
1 year
Only two days left to apply to join my new lab at the University of Manchester @MCF_UoM @FBMH_UoM! #PleaseShare #Applynow
@Alex_Doune
Alexandra Davies
2 years
My lab @MCF_UoM is #hiring a Research Technician. I'm looking for someone with experience in #iPSC & #microscopy. You will be trained in #proteomics and the project will tackle the mechanisms underlying rare neurological diseases. Apply now! https://t.co/YIAYh70a85 #pleaseshare
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@Alex_Doune
Alexandra Davies
2 years
My lab @MCF_UoM is #hiring a Research Technician. I'm looking for someone with experience in #iPSC & #microscopy. You will be trained in #proteomics and the project will tackle the mechanisms underlying rare neurological diseases. Apply now! https://t.co/YIAYh70a85 #pleaseshare
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jobs.manchester.ac.uk
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@labs_mann
Matthias Mann Lab
2 years
1/7 @labs_mann and Georg Wallmann @GeorgWa are proud to announce alphaDIA, our open source, next generation DIA search engine. Check out the preprint @biorxivpreprint https://t.co/2HuOd1AJMy
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@Alex_Doune
Alexandra Davies
2 years
Was a pleasure to collaborate with my former PhD supervisor, Scottie Robinson @TheCIMR, on this fantastic paper, just out in @JCellBiol. 40 years after Scottie discovered the #clathrin adaptor AP-1, she is still revealing surprises about its function! https://t.co/kEsi2vjVZ0
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@Alex_Doune
Alexandra Davies
2 years
I'm delighted to have received a Springboard award from @acmedsci and excited about where it will spring my lab to! πŸͺΊ Watch this space for a research technician position supporting #iPSC #raredisease modelling and #proteomics!
@MCF_UoM
Division of Molecular and Cellular Function UoM
2 years
We are thrilled to announce that @Alex_Doune has secured the Springboard Award from the @acmedsci! @FBMH_UoM https://t.co/EGyiBgbvVq
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@AbellJonny
Jonny Nixon-Abell
2 years
Post doc: https://t.co/kub9sW7eLR Research Assistant:
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@Alex_Doune
Alexandra Davies
2 years
Thanks to the Wahlig family for bringing us all together to learn about HSP. Another wonderful meeting! #TWS2024 #TreatHSP #raredisease
@szuchner
Stephan Zuchner, MD, PhD
2 years
Wonderful Tom Wahlig Symposium on HSP research in Erlangen, Germany. What a great tradition!
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@Alex_Doune
Alexandra Davies
2 years
Was an absolute pleasure to host you @ScheffoldM
@ScheffoldM
Marlene Scheffold
2 years
Back in Boston after 2 amazing weeks at Manchester learning Proteomics from @Alex_Doune as part of my project @DEF_Lab_HMS. So grateful to Alex for teaching me and to @Boehringer MD Fellowship for funding my stay. Still in awe of the exciting research and the enchanting city.
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@PliotasGroup
Pliotas Group
2 years
We have a 3-year @BBSRC postdoc available in Manchester @MCF_UoM @FBMH_UoM @UoMMIB to utilise #EPR spectroscopy to address protein dynamics with @A_Politis1 and @JeskoKoehnke on board. Deadline for applications is on the 5th of March. Please retweet
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jobs.manchester.ac.uk
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@MCF_UoM
Division of Molecular and Cellular Function UoM
2 years
Message from our new member: @LabBuckley is searching for outstanding researchers to join us as we move to MCF. We use optogenetics within zebrafish brains and mESC models to study how cells build organs. Postdoc: https://t.co/7HLI7UIu2k RA: https://t.co/PjP2rs23Pr
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@Alex_Doune
Alexandra Davies
2 years
So excited to see this paper out! 🎊 Incredible work from @DEF_Lab_HMS using #protein #mislocalisation phenotypes as a #drugscreen to identify a drug that restores the cellular distribution of ATG9A in AP4-deficient neurons and increases #autophagy flux. So cool! #CureAP4 #neuro
@DEF_Lab_HMS
Ebrahimi-Fakhari_Lab
2 years
This week we @BostonChildrens @FMKirbyNeuro report in @NatureComms a cell-based phenotypic high-throughput assay for AP-4-related #hereditaryspasticparaplegia. Screen of ~29K compounds with @Astellas identified BCH-HSP-C01 πŸ‘‰πŸ½ #raredisease @CureAP4 @CureSPG50 @SpasticParapleg
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