Argyris Politis
@A_Politis1
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HDX-MS of Membrane Proteins EPSRC Research Fellow & Group Leader University of Manchester School of Biological Sciences & Manchester Institute of Biotechnology
Manchester, United Kingdom
Joined March 2017
New paper from our group reviewing the use of HDX-MS in micelles and membranes for biopharmaceutical development. Congrats to Charlotte!
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RT @masstruct: đź“Ł Great News!!.We are excited to participate #ASMS2025 with lots of networking and innovation.
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Check out our new paper and software on how to automatically process data from multipass cyclic HDX-MS experiments:
onlinelibrary.wiley.com
Hydrogen/deuterium exchange-mass spectrometry (HDX-MS) is a powerful tool for studying protein structure and dynamics. As a bottom-up LC-MS technique, its success largely depends on peptide identif...
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RT @masstruct: 📢 We are having exciting PhD opportunities in our group @BSRC_Fleming. 👉 Check this link:
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A fully funded Phd studentship is available in collaboration with the groups of Graham Pavitt and Alan Roseman at the university of Manchester:.
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RT @NatureComms: Researchers from @omasstx and @Politis_Lab use HDX-MS to gain insight into structural dynamics of β1AR upon ligand binding….
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I am pleased to see this paper on a GPCR using HDX-MS to be published today - great collaboration with OMass Therapeutics @omasstx:
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A new paper demonstrating the power of cyclic ion mobility and HDX-MS for membrane proteins has accepted in JASMS. Congrats to Juan and Zulaikha!.
pubs.acs.org
Hydrogen/deuterium exchange mass spectrometry (HDX-MS) has evolved as an essential technique in structural proteomics. The use of ion mobility separation (IMS) coupled to HDX-MS has increased the...
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RT @dkwilson2: #HDX2024 Damon Griffiths is talking about how great cyclic ion mobility is for HDX-MS. Apparently, with multiple passes, it….
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An exciting PhD opportunity in my group in Manchester :
findaphd.com
PhD Project - (MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery at The University of Manchester, listed on FindAPhD.com
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RT @Politis_Lab: Check out our latest publication in @an_chem, where we integrate cyclic ion mobility (cIM) into HDX-MS workflows to enhanc….
pubs.acs.org
Hydrogen/deuterium exchange-mass spectrometry (HDX-MS) has emerged as a powerful tool to probe protein dynamics. As a bottom-up technique, HDX-MS provides information at peptide-level resolution,...
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Our new paper on cyclic ion mobility for HDX-MS is now out. Congrats to Damon for excellent work and thanks to Waters for continuing support.
pubs.acs.org
Hydrogen/deuterium exchange-mass spectrometry (HDX-MS) has emerged as a powerful tool to probe protein dynamics. As a bottom-up technique, HDX-MS provides information at peptide-level resolution,...
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We are looking for research technician in my group in Manchester. Please get in touch if interested:.
jobs.manchester.ac.uk
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Excited to visit Bristol Biochemistry and present our work on HDX-MS of membrane proteins.
No Thursday seminar this week but next week we are pleased to be hosting @A_Politis1 with his talk entitled: . 'Deciphering the structural dynamics of membrane proteins by HDX-MS'. Location : Ada Lovelace SM1 at 1pm on Thursday the 22nd of February.
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HDX-MS can be a powerful tool to probe dynamic signatures of GPCRs. See the new preprint from our group. A great collaboration with OMass @omasstx :
biorxiv.org
G-Protein Coupled Receptors (GPCRs) constitute the largest family of signalling proteins responsible for translating extracellular stimuli into intracellular functions. When dysregulated, GPCRs drive...
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RT @PliotasGroup: We have a 3-year @BBSRC postdoc available in Manchester @MCF_UoM @FBMH_UoM @UoMMIB to utilise.#EPR spectroscopy to addres….
jobs.manchester.ac.uk
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I am very pleased for our new preprint on cyclic HDX-MS of membrane proteins. Special thanks to Damon Griffiths and Waters for all of their support on this challenging project:
lnkd.in
This link will take you to a page that’s not on LinkedIn
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A great opportunity for a research technician post in HDX-MS - application deadline 8th Dec:
jobs.manchester.ac.uk
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