Peter Adams🇪🇺🇺🇳
@AdamsBioAging
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Director NCI-designated Cancer Genome and Epigenetics Program at SBP, Co-Editor-in-Chief Aging Biology Journal, Road/Gravel/Mtn Cycling, Wolf Pack Cycling.
San Diego, CA
Joined August 2020
New road bike. S-WORKS Tarmac SL7, Campy SR wireless and disc, Campy Bora Ultra WTO wheels👍 No excuses now😧
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Yes, this was a great meeting and wonderful hospitality. Thanks @MariaMMota2 and colleagues @GIMM_Institute I learnt about “macrophAGING” and “immunoneuroendocrine” aging. Thanks Claudio Franceschi! GIMM also had some inspiring videos which I hope they post.
Three fantastic days in Lisbon for the @GIMM_Institute Festival. Insightful talks and great conversations!. My favorite quote came from @MariaMMota2 . "Scientists are optimists. They admit when they don’t know but believe one day they will."
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Great work, Matt @MattYousefzadeh I enjoyed listening to this. Effects of Rapamycin on Immune Rejuvenation | Asst Prof Matt Yousefzadeh - YouTube
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RT @agingdoc1: Unlocking longevity through the comparative biology of aging. @ChRechsteiner @ Gorbunova/ Seluanov lab @UofR. .
nature.com
Nature Aging - Rechsteiner and colleagues explore how studying lifespan and disease resistance across species reveals natural adaptations that promote longevity. The authors summarize new...
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Cytosolic DNA crosstalk in senescence: a new axis of inflammatory signaling-------I'm excited to collaborate with Joao Passos, John Sedivy, Zhixun Dou @nneretti to understand mechanisms and interventions targeting cytoplasmic chromatin in senescence .
embopress.org
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Well said…….
How do we actually Make America Healthy Again?. It’s no secret that I’m not impressed by the recent push to remove food dyes, swap seed oils for tallow, or change the source of sugar in soda. Whenever I push back, I’m seeing a lot of the same response. “Well, at least it’s a step.
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RT @YicsaC: Our newly updated yICSA website is here! Check out our activities & stay tuned for updates. Next stop:….
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RT @LammingLab: We are looking to fill the shoes of our lab manager/technician who is starting medical school Monday! If you know someone w….
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Interesting results with GLP1 agonists from new @UCSDHealth faculty Michael Corley.
Ozempic and aging.
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On the similar subject - I was listening to this this morning on my morning walk
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Fascinating! My new favourite subject……Brain control of energy homeostasis: Implications for anti-obesity pharmacotherapy: Cell
cell.com
Advances in mapping how the brain regulates energy homeostasis, together with progress in peptide-based pharmacotherapy, highlight emerging opportunities for obesity treatment with the potential to...
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Adarsh has a postdoc lined up in great lab of @corina_amor_MD at Cold Spring Harbor Lab. More great stuff to come, I'm sure.
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A role for proto-oncogene Cyclin D1/CCND1 in senescent cells has important implications for the relationship between aging and cancer. An oncogene physiologically upregulated in aged senescent cells🤔??!!.
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Pharmacologic inhibition by FDA-approved CDK6 inhibitor improves physical function and suppresses frailty in aged mice.
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Adarsh confirmed paradoxical expression of cell cycle genes Cyclin D1 and CDK6 in senescent cells and defined a role in promoting DNA damage, cytoplasmic chromatin fragments (CCF) and inflammation/SASP.
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I'm excited to share this new MS led by fabulous PhD student Adarsh Rajesh "Targeting Cyclin D1-CDK6 to Mitigate Senescence-Driven Inflammation and Age-Associated Functional Decline".
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More fascinating work from @LammingLab.
Tissue-Specific Effects of Dietary Protein on Cellular Senescence Are Mediated by Branched-Chain Amino Acids.
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Most adult human diseases are caused by aging, over or poor nutrition, lack of exercise and combinations of. We can modulate these factors individually, but have little information on how to combat more than one together. Hence this study on rapamycin in aging + high fat diet.
Rapamycin Reverses the Hepatic Response to Diet-Induced Metabolic Stress That Is Amplified by Aging. 👉 “These findings demonstrate that aging intensifies hepatic sensitivity to metabolic stress and identify rapamycin as a promising therapeutic to counteract age-related liver
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UC Irvine is recruiting! Tenure-track faculty position, translational research in cancer biology, Otolaryngology - HNS & Anatomy/Neurobiology (Application due date: 08/29/2025). I am always impressed by the science on my visits to UCI.
recruit.ap.uci.edu
University of California, Irvine is hiring. Apply now!
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Great review from Felicia Lazure and Ana Gomes.
Cancer progression through the lens of age-induced metabolic reprogramming.
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Geoscience LA meeting - always a great mtg!! Sept 5 2025.
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