Cheyenne Rechsteiner
@ChRechsteiner
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PhD student in the Gorbunova/Seluanov lab @UofR. Passionate about the #epigenetics of #aging.
Joined September 2021
Unlocking longevity through the comparative biology of aging @ChRechsteiner @ Gorbunova/ Seluanov lab @UofR
https://t.co/aqdpbPQ84B
nature.com
Nature Aging - Rechsteiner and colleagues explore how studying lifespan and disease resistance across species reveals natural adaptations that promote longevity. The authors summarize new...
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Online now! ✨REVIEW: Rechsteiner et al explore how studying lifespan and disease resistance across species can reveal natural adaptations that promote longevity https://t.co/Kz1fmtTjji
nature.com
Nature Aging - Rechsteiner and colleagues explore how studying lifespan and disease resistance across species reveals natural adaptations that promote longevity. The authors summarize new...
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Unlocking longevity through the comparative biology of aging https://t.co/yRfCCZBeeA
nature.com
Nature Aging - Rechsteiner and colleagues explore how studying lifespan and disease resistance across species reveals natural adaptations that promote longevity. The authors summarize new...
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Happy to share our latest manuscript describing rejuvenation of cells from the mouse model of premature aging ERCC1 by partial reprogramming, even in the absence of proper DNA repair. Thank you to @trickpaine, members of the Ocampo Lab, and collaborators!
frontiersin.org
Unlike aged somatic cells, which exhibit a decline in molecular fidelity and eventually reach a state of replicative senescence, pluripotent stem cells can i...
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🐭 DNA methylation age in Ercc1, LAKI, Polg, and Xpg mouse progeria models. Ercc1 mice, with DNA repair deficits, show significant epigenetic aging, mirroring results observed in humans. Exciting link between DNA repair and epigenetic clocks. #AgingScience #DNARepair
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Very excited to share the latest paper from our laboratory where we investigated the adverse effects of in vivo reprogramming. We hope that our work can help this very promising field to move forward. Congratulations to the authors and collaborators!
nature.com
Nature Aging - Partial reprogramming to enhance regeneration and mitigate age-related phenotypes is limited by toxicity. Parras et al. report a transgenic reprogrammable mouse strain with...
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Happy to announce the publication of our novel aging clock based on the analysis of chromatin accessibility by ATAC-seq! Amazing work of current and past members of @OcampoLab, collaborators, and members of the team at @epiterna_
https://t.co/A7Y8UpLB4B
link.springer.com
GeroScience - The establishment of aging clocks highlighted the strong link between changes in DNA methylation and aging. Yet, it is not known if other epigenetic features could be used to...
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I am happy to announce that my paper investigating the differences between the gut microbiomes of rural and urban communities in Senegal is published in iScience! https://t.co/L21LuwEvy0 Thank you to all of my co-authors, especially @PSeksik
cell.com
Microbiology; Microbiome; Developmental biology
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A team led by Alejandro Ocampo at @unil describes a novel, multiomic #epigenetic aging clock based on chromatin accessibility & transcriptomics in PBMCs, using ATAC-Seq & RNA-Seq. See how it compares to the Horvath or Hannum clocks: https://t.co/VskI3XsGgn
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I am very happy to announce the generation of a novel epigenetic clock based on age-associated changes in chromatin accessibility!!
biorxiv.org
The establishment of aging clocks based on age-associated changes in DNA methylation has highlighted the strong link between epigenetic alterations and aging. However, the connection between DNA...
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