Out today in @NatureComms, the last chapter of my PhD thesis @institutpasteur @Microbio_IP 🥳 We found that RNase J, the major RNA degradosome RNase of Helicobacter pylori, is post-translationally regulated by acetylation. We solved the RNase J… (1/4) https://t.co/fpeGe1mHCU

I am very happy to share our latest study on ciprofloxacin resistance instability in P. aeruginosa during periods of drug restriction. A fantastic collaboration @PabloLaborda95, @rug_lrs, JL Martínez, Søren Molin & Helle Johansen🥳 @CNB_CSIC @DTUBiosustain https://t.co/bXvsrClkGc

Ceftazidime-avibactam (a last resort drug) use selects multidrug-resistance and prevents designing collateral sensitivity (CS) based therapies against P. aeruginosa (no robust patterns of CS emerge). Happy to see it published! 🥳 @CNB_CSIC @microHUSE https://t.co/LhtzeuQKQH

Flow Cytometry Operator/Specialist at the FACS Core Facility (FCF) of the Biozentrum, University of Basel (60-80%) https://t.co/63oyfjSjyY @biozentrum #Biozentrum #Basel #research #science #joboffer #hiring #cytometry #operator

Poke bacteria with a sharp needle and they poke back in just a few seconds! Congratulations to Mitchell (and others) for this analysis of Pseudomonas #T6SS assembly in response to membrane damage! Collaboration with Rod Lim's lab @biozentrum + @SNIunibas! https://t.co/bWRCZTsgmE

You can find me in bluesky @atejadaarranz.bsky.social 🔵

For the past two years, we have been working on a novel approach to identify origins of transfer by conjugation in plasmids from any bacterial species. We are thrilled to see this work now published in @NatureMicrobiol after thorough peer review! https://t.co/TpTxRy7jjd

Excited to share our work published in @NatureBiotech! We uncover and characterize a unique and highly versatile ancestral form of CRISPR-Cas12a (ReChb)! A big thanks to the whole team. 🧬 https://t.co/7UgQAzzthP #SynBioLab @CICbioGUNE @IgorTascon @BeiselLab @FUNDELA1

Extremely happy to see the final version of our paper "The expression of integron arrays is shaped by the translation rate of cassettes" out in @NatureComms 🥳!!! Thanks to the reviewers for their valuable feedback and suggestions! https://t.co/SJ2gL2RDRq

Out now @biorxiv_micrbio, one of the main publications of my postdoc @Basler_Lab 🥳 more on this soon 😁

🚨🔬Excited to share our new paper now out in @NatureMicrobiol! Using Tn-seq + live imaging in engineered airway organoids, we explored the fitness tradeoffs P. aeruginosa faces while growing and surviving antibiotic treatment on the mucosal surface. 🔗  https://t.co/DCPVogORDv

(1/6) Really jazzed to have this out - my first @wellcometrust fellowship paper! https://t.co/uhA1c5Qv0M Can bacteria evolve resistance to competitors' T6SS weaponry? We find that the answer depends on **how many toxins** competitors are using. A thread:

For over 10 years, we've known that neighboring P. aeruginosa cells engage in rounds of H1-T6SS firing. It was unclear how this starts since H1-T6SS only fires in response to an attack. Now we know: https://t.co/u2KnfkagmK Congrats Max, Sharath, Alejandro, and others!

The @NCCR_AntiResist consortium in all its glory😀 🦠👨‍🔬👩‍🔬 #TransformingAntimicrobialResearch

Congratulations to Miro (@PlumifyM), Christy (@christy_chc), Patricia and others on a beautiful paper showing #T6SS role in spreading of Burkholderia thailandensis between infected cells: https://t.co/V8WbSv8W5B

Finally, it's online!!! Thank you so much Pablo @RiveraChemLab for every supports and our lovely colloborators @vishwachi_95 @benedict_morin @aya_iizuka @BumannLab @KhannaLabBasel

New preprint alert!! 💥An update on the #integron model! From the @jaegc lab! We found that "The expression of integron arrays is shaped by the translation rate of cassettes"! Here's a thread 🧵 You can read the full paper here:

I’m thrilled to announce that the paper from my PhD work at @CNIOStopCancer is now available online in @NatureComms ! Incredibly grateful to my supervisor @EfeyanLab, the entire MCS team and our amazing collaborators @Gsabiolab & Ajay Jain, whose expertise has made this possible!

Looking for a PhD student to join my group studying bacterial virulence factors using cryo-EM, advanced biochemistry, and molecular biology. Modern environment, amazing colleagues, and a lively city in the Top of the Netherlands! Apply: https://t.co/DCIzFW9r7q

📢 @NCCR_AntiResist will be visiting high schools in Basel from Autumn 2024 ❓ Students can learn about antimicrobial resistance (AMR) and our research to reduce this global threat. Worksheets provided. 💬 DE or EN 🚀 Register your interest now! https://t.co/ueKPpZqCBt

What a start for the PGB lab in 2024 with yet another integron story! This time we uncover how toxin-antitoxin cassettes have shaped the evolution of chromosomal integrons, turning them into giant genetic libraries for fast "à la carte" adaptation! https://t.co/Mnz7ZIJjwn