bioRxiv Microbiology
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The role of type IV pilus in the interaction of Neisseria gonorrhoeae with a corneal epithelium tissue model https://t.co/Enp01Dc78W
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Neisseria gonorrhoeae, the causative agent of the sexually transmitted disease gonorrhea, can infect intact corneal epithelium, leading to inflammation, cornea perforation, and blindness. Models for...
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Comprehensive analysis of draft genomes of two closely related Pseudomonas syringae pv. syringae phylogroup 02b strains infecting ... https://t.co/FQteDi6Dfi
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Pseudomonas syringae pv. syringae (Pss) is a cosmopolitan phytopathogen with high genomic plasticity and effector diversity, driving host adaptation and variable virulence. We sequenced, assembled,...
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Skin microbiome composition and function in the development of atopic diseases during infancy https://t.co/ZDpiFjZOqS
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Background: Atopic dermatitis (AD), food sensitization (FS), and food allergy (FA) frequently co-occur in infancy, but the factors driving distinct atopic phenotypes remain unclear. While FLG null...
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Early occurrence of Teratoramularia rumicicola in Japan: re-identification of historic strain GR1 and its pathogenic effects on ... https://t.co/7CBB6ddWJU
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Teratoramularia rumicicola is a plant pathogenic fungus infecting Rumex species. Although it was described as a new species in 2016, its fundamental characteristics, including historical occurrence,...
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Plasma Ficolins Enable Liver Macrophages to Capture Blood-Borne Bacteria by Recognizing Capsular Polysaccharides https://t.co/OZDLCxBpJr
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Ficolins are evolutionarily conserved glycan-binding lectins in plasma or on cell membranes of immune cells, yet their physiological functions remain to be defined. Here we demonstrate that plasma...
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Scaling up by looking closer: extending the range of moss-Nostoc symbioses deeper into central Europe and to new moss hosts in the ... https://t.co/ZTj6E7Jxxb
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Since their re-discovery, Moss-cyanobacterial symbioses are of increasing interest, especially Nostoc-feather-moss symbioses. Efforts to document Nostoc-feather-moss symbioses have historically been...
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Ancient Roman saltworks drive the present-day microbial community profiles in a coastal aquifer https://t.co/46iDf5xzt1
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Historical salinization from ancient saltworks can leave a long‑lasting imprint on coastal aquifers, but its impacts on subsurface microbial communities and ecosystem functioning remain poorly...
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Characterization of a lethal Crimean-Congo hemorrhagic fever virus infection model in interferon-deficient mice for studies of virus ... https://t.co/PFGzPJxL52
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Crimean-Congo hemorrhagic fever virus (CCHFV) is a highly pathogenic tick-borne virus causing severe human disease and representing a significant public health threat. The absence of licensed...
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Outer Membrane Vesicles Hijack TIM-1 for Cellular Uptake https://t.co/0EbUHSPGQ5
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Outer membrane vesicles (OMVs) are nanoscale proteoliposomes shed by Gram-negative bacteria that mediate host-pathogen interactions and hold promise as platforms for vaccines and targeted drug...
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LAP Drives Monocyte-Mediated and Extracellular Translocation of Listeria monocytogenes Across the Placental Barrier https://t.co/Tc3xMP7kfJ
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Listeria monocytogenes (Lm) is a major cause of fetal infection, yet the mechanisms by which it traverses the placental barrier remain incompletely defined. We established and validated a physiolog...
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Spatiotemporal dynamics in airborne fungi and fungal allergens across the United States https://t.co/Yp0n7qoNId
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A broad diversity of fungi can be found in the near-surface atmosphere, with both the amounts and types of airborne fungi varying across space and time. However, the specific spatiotemporal patterns...
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Scaling down-Evaluation of start-up and microbial stabilisation dynamics in five parallel laboratory-scale CSTR biogas system https://t.co/txgSQ2C27D
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Laboratory-scale continuous stirred tank reactors (CSTRs) are commonly used to study and optimise anaerobic digestion (AD), yet the time required for such systems to become representative of full-s...
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Uncovering clinically-relevant altered antibiotic responses of Staphylococcus aureus under wound infection-mimetic conditions https://t.co/OAbsiODZNo
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Chronic wound infections, most commonly caused by Staphylococcus aureus, affect 1-2% of the world's population and incur direct healthcare costs exceeding $300B per year. Bacterial susceptibility to...
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Antifungal susceptibility profile of clinically relevant species of the genus Sporothrix: establishment of Epidemiological Cutoff ... https://t.co/E6VYTjc8Db
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Sporotrichosis is a globally distributed subcutaneous mycosis caused mainly by Sporothrix brasiliensis, S. schenckii, and S. globosa. Cat-transmitted sporotrichosis, primarily caused by S. brasilie...
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Identification of DksA as a novel pro-inflammatory mediator of Pseudomonas aeruginosa under conditions mimicking chronic cystic ... https://t.co/M6vmb9eQwx
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Chronic infection with Pseudomonas aeruginosa is a major driver of airway inflammation, which plays a central role in the progression of cystic fibrosis (CF) lung disease. During long-term coloniza...
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Nutrient-limited conditions reveal the activity of a minor groove binder, MGB-BP-3, against Escherichia coli https://t.co/7ZcQUouu6Q
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Background: Antimicrobial resistance demands new antibiotics, but conventional screening in nutrient-rich media often fails to predict in vivo efficacy, especially against Gram-negative bacteria....
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MALDI-FISH for co-localization of brominated metabolites and Pseudovibrio spp. in Aplysina tissue https://t.co/YRrQX6kUzD
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Bromotyrosine-containing natural products have long been isolated from marine sponges of the order Verongiida . Recent studies have questioned the source of these natural products whether production...
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Modeling the phage properties best for therapy https://t.co/PKmVqvjT42
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The phages used to treat bacterial infections in phage therapy are commonly chosen based on their abilities to form plaques on the infecting bacterium -- on host range. In practice, phage therapy is...
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Viral infection collapses intracytoplasmic membrane integrity and autotrophic metabolism in ammonia-oxidizing Nitrosomonas europaea https://t.co/AtBvx8QdfT
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Ammonia-oxidizing bacteria (AOB) catalyze the first and rate-limiting step of nitrification. They are essential for nitrogen cycling in engineered and natural environments, yet little is known about...
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The Bacillus subtilis class A penicillin-binding protein 4 (PBP4) requires an accessory protein RpdA https://t.co/ccxeh2dURO
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Peptidoglycan (PG) synthesis is essential to maintain cell integrity during bacterial growth and division. In Bacillus subtilis, PG synthesis involves class A PBPs that act independently and class B...
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