André Carvalho
@AndrePCarvalho
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🇵🇹Postdoc https://t.co/NyXbvrJUvs I PhD Institute Pasteur; #antimicrobialresistance #integrons #microbiology #genetics
Comunidade de Madrid, Espanha
Joined February 2019
Extremely happy to see the final version of our paper "The expression of integron arrays is shaped.by the translation rate of cassettes" out in @NatureComms 🥳!!! Thanks to the reviewers for their valuable feedback and suggestions! .
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RT @jaegc: With a bit of a lag for X. 🧪 Finally out after peer review, our work showing that "Mobile #Integrons carry Phage Defense Syste….
science.org
Integrons are bacterial genetic elements that capture, stockpile, and modulate the expression of genes encoded in integron cassettes. Mobile integrons (MIs) are borne on plasmids, acting as a vehicle...
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RT @LauraOrtMir: 💊🔬 The environment changes everything… even antibiotic resistance! .In our last work, we explore how oxygen shapes resista….
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RT @CostaT_Lab: With @jrpenades, we challenged AI co-scientist @GoogleAI to generate hypotheses. In just 2 days, it recapitulated our unpub….
biorxiv.org
AI models have been proposed for hypothesis generation, but testing their ability to drive high-impact research is challenging, since an AI-generated hypothesis can take decades to validate. Here, we...
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RT @FlorianFournes: "The pathway to resolve dimeric forms distinguishes plasmids from megaplasmids in Enterobacteriaceae | Nucleic Acids Re….
academic.oup.com
Abstract. Bacterial genomes contain a plethora of secondary replicons of divergent size. Circular replicons must carry a system for resolving dimeric forms
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RT @BaharogluZeynep: Our paper on 🦠queuosine 34 modification of tRNA tyrosine and antibiotic response is finally out in its final form in @….
elifesciences.org
tRNA Q34 modification impacts tyrosine codon decoding and leads to proteome reprogramming in response to antibiotic stress in Vibrio cholerae.
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RT @institutpasteur: Félicitations à nos lauréats du Prix Agnes Ullmann !. @BaharogluZeynep explore l’impact des modifications de l’ARN sur….
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RT @RLeonSampedro: 🚨New preprint!! How do antibiotic-resistant bacteria grow in the human gut microbiome, even without antibiotics? 🤔 We re….
biorxiv.org
Understanding the spread of antibiotic-resistant bacteria in human-associated microbial communities, particularly in the gut microbiome, is critical for combating the global resistance crisis....
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RT @MBlokesch: Exciting times! Our latest preprint is now live 🤩!.I truly believe this is one of the most significant contributions we've m….
biorxiv.org
Our understanding of the factors underlying the evolutionary success of different lineages of pandemic Vibrio cholerae remains incomplete. Interestingly, two unique genetic signatures define the West...
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RT @M_AresArroyo: For the past two years, we have been working on a novel approach to identify origins of transfer by conjugation in plasmi….
nature.com
Nature Microbiology - Characterization of known plasmid oriT features facilitates identification of 21 oriT-containing sequence families which, alongside candidate sequence validation, expands our...
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RT @jaegc: Finally out after peer review, our update on the integron model showing that translation rates of cassettes in first position in….
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Thanks again to all co-authors @alberto_hca , @filipatr , Lucía García-Pastor, Ester Vergara, Aranzazu Buendía, Teresa García-Seco. And a very special thanks to @jaegc !!!.
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Check below for a thread!! 👇🧵.
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RT @JGamma3: In our new study, we show that plasmid carriage can affect the frequency of microindel mutations in their host: .
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Checkout the last work from the lab!! Really important work for the field of integrons! 👏🏻.
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RT @jaegc: Finally out after peer review. The first SuperIntegron-less Vibrio cholerae. and it is virtually identical to the WT! https://….
academic.oup.com
Abstract. Integrons are genetic elements that increase the evolvability of bacteria by capturing new genes and stockpiling them in arrays. Sedentary chromo
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RT @BruriaSamuel: Meet The Shielded Plasmid🛡️🧬. Our new @Nature paper reveals how plasmids outsmart bacterial defenses during conjugation.….
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RT @JGamma3: Quite excited about the latest "Universal rules govern plasmid copy number", with my new group: @paula_micro @BioNacho & @Jero….
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RT @Jero_RB: Also, don't forget to check this amazing paper from @lingchongyou lab, where they independently discovered similar plasmid sca….
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RT @Jero_RB: Check out our new work to read about one of the most surprising (and amazing) results of my career: . Plasmids are governed by….
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