Basler Lab
@Basler_Lab
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Unraveling the secrets of bacterial injection needles .. (among other things)
Basel, Switzerland
Joined August 2010
The prey (blue) multiply, don't move and produce capsule (purple). The predators (red) move towards prey and attack non-kin. They divide only if they lyse prey. The defenders (orange) move randomly and defend themselves by retaliation (divide if they lyse a cell). Who wins?
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Check out the NotebookLM powered interactive Q&A: https://t.co/REyeWg0mIP This is based on the scientific literature and the simulation code. Literature is cited in the help and the documentation. Extremely helpful!
sites.google.com
For more details and explanations, feel free to chat with this NotebookLM. It is very useful! The answers are based on the simulation code, the detailed documentation and the scientific manuscripts...
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Major update to BacFighT6: https://t.co/0UnqXBR6Zf Simulate the role of motility/chemotaxis, capsule production, activation by autoinducers, contact dependent killing, kin-exclusion, foraging and more. Long simulations, extensive data import/export and analysis. Interactive Q&A!
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To make our research more approachable, I used #Gemini to develop (mostly by #vibecoding) a simulation of #T6SS mediated bacterial interactions. I hope that you'll have as much fun as I have with this and that you'll learn something new! https://t.co/0UnqXBQz9H
sites.google.com
The purpose of this web site is to showcase bacterial interactions mediated by the Type VI secretion system. The simulation, the documentation, and the explanations are under development. Most of...
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Happy to help William with his high school graduation project: https://t.co/28E1ZZnNE3
https://t.co/Vh6dvmvx8b Congratulations! Thanks to @biozentrum and @NCCR_AntiResist for support.
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Thank you, Katrin, for a great news article: Damaged but not defeated: Bacteria use nano-spearguns to retaliate against attacks https://t.co/LDJYx5zZDq And the @SNIunibas for producing this video summary: https://t.co/K8N7mBFZ77
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Poke bacteria with a sharp needle and they poke back in just a few seconds! Congratulations to Mitchell (and others) for this analysis of Pseudomonas #T6SS assembly in response to membrane damage! Collaboration with Rod Lim's lab @biozentrum + @SNIunibas! https://t.co/bWRCZTsgmE
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Apply now for the prestigious and independent #BiozentrumPhDFellowships. Great science. Unique rotation-based selection of research group and other incentives. The summer call is open until May 18, 2025. https://t.co/LzyyXOQOHb
@biozentrum @UniBasel_en
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Assistant/Associate Professor in Structural Biology, Biological Imaging or Biophysics https://t.co/sGoDEaeQJP
#Biozentrum #Basel #research #science #joboffer #Assistant #Associate #Professor
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For over 10 years, we've known that neighboring P. aeruginosa cells engage in rounds of H1-T6SS firing. It was unclear how this starts since H1-T6SS only fires in response to an attack. Now we know: https://t.co/u2KnfkagmK Congrats Max, Sharath, Alejandro, and others!
journals.asm.org
The opportunistic pathogen Pseudomonas aeruginosa harbors three different Type VI secretion systems (H1, H2, and H3-T6SS), which can translocate toxins that can inhibit bacterial competitors or...
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Happy to support Gabriela's successful high school graduation project! More information here: https://t.co/Gri2H3cVOi Thanks to @biozentrum and @NCCR_AntiResist for support as well as to @SJf_CH for organizing the competition!
inspiration.sjf.ch
Chemie | Biochemie | Medizin Gabriela Basler, 2004 | Oberwil, BL Bacteria are highly adaptable single-cell organisms, which developed mechanisms to allow them to thrive in diverse environ...
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Thank you, Katrin (@biozentrum), for a great summary of our work! https://t.co/WS6dbZGdiV
Exciting discovery by @PlumifyM & @Basler_Lab: The intracellular pathogen #Burkholderia uses the #T6SS nano-speargun to spread in the body without being recognized by the immune system. @biozentrum @Unibasel_en @cellhostmicrobe @ERC_Research
https://t.co/wzhPxO9INC
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Congratulations to Miro (@PlumifyM), Christy (@christy_chc), Patricia and others on a beautiful paper showing #T6SS role in spreading of Burkholderia thailandensis between infected cells: https://t.co/V8WbSv8W5B
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NEW: MSc in Physics of Life – training in cutting-edge research at the interface of physics, mathematics, engineering and life sciences. Apply now and be one of the first students of the program. Scholarships available. @biozentrum @UniBasel_en
https://t.co/xckoLVjdHD
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CONGRATS, Andrea!!
❗️BIG NEWS❗️I will be joining the @DMF_UNIL as assistant professor in Feb 2024!!! In my lab we will continue to use different live-cell techniques 🔬to study cell envelope biogenesis in distinct diderm organisms🦠. (1/3)
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Assistant/Associate Professor in Molecular, Cellular or Systems Biology https://t.co/QyeZbYGkdg
@biozentrum @UniBasel_en
#Biozentrum #Basel #research #science #professorship
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Big thanks to @EMBO for this amazing recognition, @biozentrum and @UniBasel_en for the support but most importantly current and past members of my lab for their curiosity, hard work but also all the fun we have had! Can't wait to see what we might discover together in the future!
EMBO announces the election of 69 new members and associate members who join the EMBO community of more than 2,000 leading life scientists in Europe and beyond https://t.co/vvu8lhuR5F
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Apply now for the prestigious and independent #BiozentrumPhDFellowships. Great science. Unique rotation-based selection of research group and other incentives. The summer call is open until 25 May 2023. https://t.co/t78Q4FkZrm
@biozentrum @UniBasel_en
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