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Basler Lab

@Basler_Lab

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Unraveling the secrets of bacterial injection needles .. (among other things)

Basel, Switzerland
Joined August 2010
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@Basler_Lab
Basler Lab
25 days
The prey (blue) multiply, don't move and produce capsule (purple). The predators (red) move towards prey and attack non-kin. They divide only if they lyse prey. The defenders (orange) move randomly and defend themselves by retaliation (divide if they lyse a cell). Who wins?
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@Basler_Lab
Basler Lab
25 days
Check out the NotebookLM powered interactive Q&A: This is based on the scientific literature and the simulation code. Literature is cited in the help and the documentation. Extremely helpful!.
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@Basler_Lab
Basler Lab
25 days
Major update to BacFighT6: Simulate the role of motility/chemotaxis, capsule production, activation by autoinducers, contact dependent killing, kin-exclusion, foraging and more. Long simulations, extensive data import/export and analysis. Interactive Q&A!.
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@Basler_Lab
Basler Lab
1 month
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@Basler_Lab
Basler Lab
1 month
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@Basler_Lab
Basler Lab
1 month
To make our research more approachable, I used #Gemini to develop (mostly by #vibecoding) a simulation of #T6SS mediated bacterial interactions. I hope that you'll have as much fun as I have with this and that you'll learn something new!.
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@Basler_Lab
Basler Lab
2 months
Happy to help William with his high school graduation project:. Congratulations!. Thanks to @biozentrum and @NCCR_AntiResist for support.
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@Basler_Lab
Basler Lab
4 months
Thank you, Katrin, for a great news article:. Damaged but not defeated: Bacteria use nano-spearguns to retaliate against attacks. And the @SNIunibas for producing this video summary:.
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@Basler_Lab
Basler Lab
4 months
Poke bacteria with a sharp needle and they poke back in just a few seconds!.Congratulations to Mitchell (and others) for this analysis of Pseudomonas #T6SS assembly in response to membrane damage!.Collaboration with Rod Lim's lab @biozentrum + @SNIunibas!.
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@Basler_Lab
Basler Lab
4 months
RT @biozentrum: Apply now for the prestigious and independent #BiozentrumPhDFellowships. Great science. Unique rotation-based selection of….
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@Basler_Lab
Basler Lab
1 year
RT @biozentrum: Assistant/Associate Professor in Structural Biology, Biological Imaging or Biophysics. #Biozentrum….
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@Basler_Lab
Basler Lab
1 year
For over 10 years, we've known that neighboring P. aeruginosa cells engage in rounds of H1-T6SS firing. It was unclear how this starts since H1-T6SS only fires in response to an attack. Now we know:.Congrats Max, Sharath, Alejandro, and others!.
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@Basler_Lab
Basler Lab
1 year
Happy to support Gabriela's successful high school graduation project!. More information here:. Thanks to @biozentrum and @NCCR_AntiResist.for support as well as to @SJf_CH for organizing the competition!.
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@Basler_Lab
Basler Lab
1 year
Thank you, Katrin (@biozentrum), for a great summary of our work!.
@biozentrum
Biozentrum, University of Basel
1 year
Exciting discovery by @PlumifyM & @Basler_Lab: The intracellular pathogen #Burkholderia uses the #T6SS nano-speargun to spread in the body without being recognized by the immune system. @biozentrum @Unibasel_en @cellhostmicrobe @ERC_Research.
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@Basler_Lab
Basler Lab
1 year
Congratulations to Miro (@PlumifyM), Christy (@christy_chc), Patricia and others on a beautiful paper showing #T6SS role in spreading of Burkholderia thailandensis between infected cells:.
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@Basler_Lab
Basler Lab
1 year
RT @biozentrum: NEW: MSc in Physics of Life – training in cutting-edge research at the interface of physics, mathematics, engineering and….
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@Basler_Lab
Basler Lab
2 years
CONGRATS, Andrea!!.
@AVettiger
Andrea Vettiger
2 years
❗️BIG NEWS❗️I will be joining the @DMF_UNIL as assistant professor in Feb 2024!!! In my lab we will continue to use different live-cell techniques 🔬to study cell envelope biogenesis in distinct diderm organisms🦠. (1/3)
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@Basler_Lab
Basler Lab
2 years
RT @biozentrum: Assistant/Associate Professor in Molecular, Cellular or Systems Biology. @biozentrum @UniBasel_en….
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@Basler_Lab
Basler Lab
2 years
Big thanks to @EMBO for this amazing recognition, @biozentrum and @UniBasel_en for the support but most importantly current and past members of my lab for their curiosity, hard work but also all the fun we have had! Can't wait to see what we might discover together in the future!.
@EMBO
EMBO
2 years
EMBO announces the election of 69 new members and associate members who join the EMBO community of more than 2,000 leading life scientists in Europe and beyond.
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@Basler_Lab
Basler Lab
2 years
RT @biozentrum: Apply now for the prestigious and independent #BiozentrumPhDFellowships. Great science. Unique rotation-based selection of….
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