Kejia Yan
@yantwohappyyyy
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U of A Chem PhD Student from Derda lab. Peptide chemist.
Joined November 2013
Congratulations to Kejia Yan @yantwohappyyyy the lead on the most complex and comprehensive @acsJACS publications from @derda_lab to date. Big thanks to @48HourDiscovery and Dustin Maly Lab for their contribution. See "late stage reshaping" paper at https://t.co/n5CCXgCqns
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@derda_lab is taking a fresh look at molecular discovery: why always start from zero, if you can start from one? Check out the paper led by Kejia Yan @yantwohappyyyy on late stage reshaping of pre-discovered molecular landscapes, now on BioRxiv
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Exciting news from @tracy6528! 🎉 Check out her latest paper on 'Chemoenzymatic synthesis of genetically-encoded multivalent liquid N-glycan arrays' available online now. 📚🔬
nature.com
Nature Communications - Cellular glycosylation is complex and heterogeneous, which is challenging to reproduce synthetically. Here, the authors report on enzymatic remodelling of multivalent...
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Peptide-Hypervalent Iodine Reagent Chimeras: Enabling Peptide Functionalization and Macrocyclization (Jerome Waser and co-workers) @LcsoLab
onlinelibrary.wiley.com
The introduction of highly reactive hypervalent iodine reagents—ethynylbenziodoxolones (EBXs)—onto peptides is described. These peptide-EBX chimeras can be used as versatile handles for peptide/pro...
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Very happy to see this joint effort with @GongChenLab @J_A_C_S. We both love rarely visited conformational space. Gong lab’s reaction implants a rigid aryl brace between Asp, His, and Asn residues, delivering stunning structural motifs.
pubs.acs.org
The three-dimensional structure of medium-sized cyclic peptides accounts for their biological activity and other important physiochemical properties. Despite significant advances in the past few...
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Today is the last day of our intern Allison. It's so nice to have you in our group for the past 4 months. All the best to your future adventures!
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Paper just published. That was fast! Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows - Faucher - Israel Journal of Chemistry - Wiley Online Library
onlinelibrary.wiley.com
Macrocyclic peptides are attractive for chemoproteomic applications due to their modular synthesis and potential for high target selectivity. We describe a solid phase synthesis method for the...
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ChatGPT converts lists of references in BibTeX format. I want to cry. OpenAI, I love you.
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OMG it finally works!! 🚀🚀🚀 I got @OpenAI to draft emails 📧 for me in the background 🤯 This christmas I built an email assistant ( https://t.co/3ALSbIJNlG) that automatically drafts email replies behind the scenes no chrome extension necessary, here's the story 👇
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I support increasing federal funding for grad students and postdocs! Join me in sending the message that we care about graduate students and postdoctoral scholars by emailing your Member of Parliament #SupportOurScience
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Genetically-Encoded Discovery of Perfluoroaryl-Macrocycles that Bind to Albumin and Exhibit Extended Circulation in-vivo https://t.co/kKSB1MuPid
#bioRxiv
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Congrats Tracy!
Big up to Tracy (Chih Lan) Lin @tracy6528, @miratsojitra, Eric Carpenter and others @derda_lab with @MatthewMacaule4 and @Lowarylab for release of the new Liquid N-Glycan Array (LiGA) made via Chemoenzymatic Synthesis. Check it out!
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Tetrodotoxin from @DirkTrauner group in @ScienceMagazine this week!
science.org
A dipolar cycloaddition and ruthenium-catalyzed oxidation enables comparatively efficient synthesis of a potent neurotoxin.
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It's here–the deepest, sharpest infrared view of the universe to date: Webb's First Deep Field. Previewed by @POTUS on July 11, it shows galaxies once invisible to us. The full set of @NASAWebb's first full-color images & data will be revealed July 12: https://t.co/63zxpNDi4I
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125th Birthday: Georg Wittig: Nobel Laureate in Chemistry well-known for the Wittig reaction https://t.co/lSOdFoHVcb
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One of our "Young Investigators," Arunika Ekanayake from University of Alberta, presents her very well received "Genetically Encoded Fragment-Based Discovery, GE-FBD, from Covalent and Non-Covalent Pharmacophores" talk. #Peptides2022
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Our star undergrad @ryannqiu is presenting a poster at APS. Check out the poster number YI-P098 today!! #Peptide #Ligand #PhageDisplay #APS #APS2022 #FutureOfPeptideDiscovery
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My colleague @ARUNIKAEKANAYA1 is presenting in #APS2022 on Tuesday (June 14th) 8:25 about her fantastic work: Genetically Encoded Fragment-Based Discovery (GE-FBD) from Covalent and Non-Covalent Pharmacophores #Peptides2022
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