Dirk H. Trauner
@DirkTrauner
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Penn Integrates Knowledge Professor, Natural Product Aficionado, Photopharmacologist, Fox Terrierist, and Unfulfilled Architect. #firstgen
Philadelphia, PA
Joined December 2017
Watch out for that photon, cholesterol! Check out our latest contribution to photolipids, in a great collaboration with Michael Zott and Luca Laria. @cholsterol @photoswitches
Development of Photoswitchable Cholesterol Derivatives through Side Chain Replacement | Journal of the American Chemical Society
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[6+4] Cycloadditions! Introducing our first dive into this fascinating subject in a very enjoyable collaboration with Ken Houk and his team. Congrats to Harrison and Tufan! https://t.co/lBNsuW8Xaz
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As my memory is not as good anymore as it once was, I am excited to share this collaboration with Christina Alberini (NYU) with you:
nature.com
Translational Psychiatry - A prodrug targeting CIM6P/IGF2R enhances memory in healthy mice and reverses deficits in an Angelman syndrome mouse model
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It was wonderful to return to UC Berkeley and deliver a lecture with Clayton Heathcock in the audience.
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How did illegal vapes from China flood our neighborhoods and schools?
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Thrilled to return to UC Berkeley for the Clayton Heathcock Lecture on November 4! @Clayton5235
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Excited to speak at Princeton Bioengineering this Thursday, October 9. https://t.co/OJuH53ajjE
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Just out: Our first paper on an exciting collaboration with the Brenner Laboratory using functionalized lipids to understand and optimize Lipid Nanoparticles:
nature.com
Nature Nanotechnology - Preventing endosomal damage sensing or using lipids that create reparable endosomal holes reduces inflammation caused by RNA-lipid nanoparticles while enabling high RNA...
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Introducing the bionic azobenzene cell, AKA "Photocell", capable of modulating the viscosity of its internal membrane systems with light. I am still amazed how many photolipids cells can gobble up and accommodate. A wonderful collaboration with Howard Riezman, Suihan Feng,
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Your brain volume decreases every year after 30. This is why focus fades, names slip, and why thinking feels… slower. Lion’s Mane helps support memory, protects neurons, and encourages new neural pathway growth. This is the best one I’ve found 👇
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Just out: Our collaboration with Eric Schelter & Randall Wilharm @SchelterGroup on parsing the fascinating photochemistry of lanthanides with azobenzene photoswitches. A deep dive into light and rare earths en route to more efficient separations. @VagelosEnergy @PennChemistry
Breaking a Lewis Acidity Trend for Rare Earths by Excited State Quenching | Journal of the American Chemical Society @DirkTrauner @Penn @PennChemistry
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My opening comments at #LINO25. Let's make sure others enjoy and understand the benefits of science. https://t.co/IVmVaScVm0
timeshighereducation.com
Frances Arnold says US science is ‘paying the price’ for not explaining benefits of research funding for ‘far too long’
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Join us today as Michael Zott and Daniel Zuschlag share their work with @DirkTrauner on the synthesis of isosteroidal alkaloids!! https://t.co/8gi0jW6UNK Key reference: @J_A_C_S 2025, 147, 3010-3016. https://t.co/9D9w1NltaN Thanks to @MBalletti2 for editing and hosting!
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Greetings from the GRC on Artificial Molecular Switches and Motors! It’s exciting to see how the field has grown and is moving toward everyday applications—think photoswitchable tattoos!
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These cozy knitted stockings are perfect for keeping your feet warm on chilly winter nights. Whether you’re lounging around the house, watching TV, or wearing slippers or shoes, they add comfort and style to your everyday moments.
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I love the Hoya carnosa in my office climbing on polytwistane.
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I had a great time at the University of Rochester as the Victor Chambers Lecturer! And I really enjoyed the amazing George Eastman House and Museum, built by a millionaire (nowadays billionaire) who was civic minded and kept a low profile.
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We have updated our "Chemical Neuroscience" course to include pentameric ligand-gated channels and the first GPCRs. https://t.co/T6rqPnOXMq
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