Vigneshwaran Venkatesan
@vigneshvnkt
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Postdoc - @NaldiniLab Ph.D. - @SaravanabhavanT @CSCR_CMC_inStem
Milan, Italy.
Joined May 2021
Check out our latest review article, where we dive into recent innovations in gene editing technologies. Published in Advanced Science https://t.co/s3SA1Uotu9
@CSCR_CMC_inStem @DBT_inStem @DBTIndia
#geneediting #genetherapy
advanced.onlinelibrary.wiley.com
This review article delves into the cutting-edge advancements in gene editing technology, with a particular focus on prime editor proteins and their engineered variants. The authors provide a...
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The gut microbiome signature from different diets in >20,000 individuals. Red meat intake correlated with reduced cardiometabolic health; the opposite for plant-based foods or in omnivores with enriched plant-based intake https://t.co/IWEOqUMcxB
@NatureMicrobiol @nsegata
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Our work and my first author article is online now. We describe our therapeutic editing strategy for treating β-hemogobinopathies. Happy reading and a very happy new year :) https://t.co/1Ayl8ytIXT
@SaravanabhavanT @vigneshvnkt @CSCR_CMC_inStem @BioMedCentral
#CRISPR #GeneTherapy
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New publication from our lab showing therapeutic dual-beneficial mutations gene editing for the gene therapy of sickle cell disease and β-thalassemia. https://t.co/YNgKOHRK8u
@DBTIndia @CSCR_CMC_inStem @DBT_inStem @OffCMCVellore @Prathibhapbc
#SickleCellDisease #GeneTherapy
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I’m excited to share our latest study led by @GiuliaPasquesi out today in @CellPressNews , uncovering a new way transposons have been repurposed for human interferon signaling! Read on for a thread on cryptic splice variants, decoy receptors, and viruses (1/N) 👇🧵
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I am truly honored and deeply grateful to have been selected as a recipient of the prestigious Sun Pharma Science Scholar Award. Dedicating this award to @SaravanabhavanT and the team for their constant support. Thanks to @SunPharma_Live for giving me this opportunity.
We are excited to announce the winners of Sun Pharma Science Foundation’s ‘Science Scholar Awards’ 2023. We hope this recognition encourages these young minds to pursue research as a career and commit themselves towards the advancement of science. #ReachingPeopleTouchingLives
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Super pleased to see this out now in @NatureComms 🎉 - it's been a big team effort to get to this point! Give it a read if you're interested in beta thalassemia and cellular model systems for red blood cell diseases 🩸🧫🔬 https://t.co/t3mGiKLUl1
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You won @Prathibhapbc !!! As a @Naruto_Anime_EN fan, I suggested some cool ninja-based cartoons for the cover page - like a ninja making a cut with the katana in the genome to create an HPFH deletion. Didn't work out in the end.🤣 Now added to my bucket list. やってみましょう
New issue of @MolTherapy Nucleic Acids (#MTNA) out today! On the cover: A schematic illustration of a novel #geneediting strategy for #genetherapy for Beta-hemoglobinopathies. https://t.co/bMhGoLvenY
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Farewell party for our beloved @abhirup1992 who will be joining @blobelgroup soon. Both of my favourites are joining together 🤩. Ready to witness some cool science in the upcoming days ✌🏻.
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Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies https://t.co/6MfnjBnMjO
#MTNA
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Finally this work found its home @MolTherapy #MTNA
@ScienceCrisp @CRISPR_News @CRISPR_Articles @thalindia @SickleCellUK
Our article "Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies" is online now @MolTherapy #MTNA Thank you @DBTIndia for funding! @CSCR_CMC_inStem @DBT_inStem @OffCMCVellore (1/5)
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The video version of our protocol for hematopoietic stem cell gene editing and transplantation is out now! https://t.co/YdL0vya7fr
@CSCR_CMC_inStem @DBT_inStem @DBTIndia @JoVEJournal #genetherapy #CRISPR
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What should stable surveillance be? All cause severe acute respiratory infection surveillance at all or sentinel hospitals (depending on resources), detection & investigation of clusters. Periodic serosurveys & environmental surveillance can be useful depending on pathogen. 17/n
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Accepting and rejecting papers is an archaic practice that is terrible for science. It strips peer review of its value & institutionalizes the practice of judging scientists based on where, rather than what, they publish. It's time for this system to go. https://t.co/tD1BovOzLd
elifesciences.org
eLife is changing its editorial process to emphasize public reviews and assessments of preprints by eliminating accept/reject decisions after peer review.
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A new preprint from @SaravanabhavanT lab is online! Our work focuses on creating an 11kb HPFH-like deletion for the gene therapy of β- hemoglobinopathies. https://t.co/VfNIYd8mtY
@CRISPR_News @HSC_papers @Hema_News
biorxiv.org
Reactivation of fetal hemoglobin (HbF) is the commonly adapted strategy to ameliorate β-hemoglobinopathies. However, the continued production of defective adult hemoglobin (HbA) limits the HbF...
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New preprint from our lab; Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies https://t.co/s20HB6aozi
#bioRxiv
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Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies https://t.co/lqFXs8FB3x
#bioRxiv
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