
Tomás Rodríguez
@trodriguezUMMS
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MD/PhD. IM/GI PSTP @UTSWInternalMed @ESontheimerLab @RTI_UMassChan
Joined February 2016
Congrats to our PSTP interns for completing onboarding week! We are happy to have you as part of the UT Southwestern family and look forward to supporting you in your clinical and research endeavors! @UTSWInternalMed #internalmedicine #PSTP #UTSouthwestern #FutureScientists
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#preprint alert! Want to ID proteins associated with HUSH complex-repressed proviruses in human cells? Check out the new technique (and the interesting findings) presented by @trodriguezUMMS @pillaikarthika & colleagues in this preprint @biorxivpreprint
https://t.co/YZak1jp3QD
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Join us in congratulating the talented individuals who have matched to our residency training programs! We're eager to welcome them! @UTSWNews @UTSWIMchief #thematch
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So much gratitude to @RachelSilvers11 @MartinPacesa, @trodriguezUMMS, @krammecc, @lauren_hong11, @vivi_64_, and the rest of the team, Nadia, Christina, Natasha, Manu, Emma, Teodora for making this happen! 🙏 And of course to @njakimo for continuing our Cas9 journey together! 🤝
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Excited to share our newest Cas9 out in @NatureComms! 🥳 We recombine our Sc++ enzyme (NNG) with the PID of @BKleinstiver's SpRY (NRN) to generate a PAM-flexible chimeric Cas9 = SpRYc! 🌶️ SpRYc can edit at diverse NNN loci -- take it out for a spin! 🧫
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Bioicons, Servier SMart ( https://t.co/ycQ8ed0lH5), and @Reactome are 🔥🆓#opensource tools for making figures. Built in to @inkscape like clip art! Easy to download and contribute images.
I have created Bioicons - a library of 1632+ free, high quality science illustrations in vector format easily searchable and filterable specifically for the life science community. All icons are under permissive CC0 or CC BY license. ➡️ https://t.co/H7CawgOOiJ
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Minipreps! They're a fact of life. But if they don't bring you joy, you might want to try new tactics or treat yourself to some fun new toys! Our lab has done 2,625 minipreps so far. Let me share a few tidbits about our approach and our favorite pieces of equipment. 🧵 (1/n)
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#NottheCover, but still so awesome. Co-first author and graphic artist @tse_elegans created a image highlighting our @ImmunityCP paper ( https://t.co/g2GuczUt7y) (1/3)
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I wrote an appreciation of Hermann Muller's 1922 paper about what the properties of a gene must be. Amazing insights. https://t.co/EXO6qG2zuD
academic.oup.com
Abstract. More than 20 years before DNA was identified as the hereditary material, the Drosophila geneticist, Hermann Muller, envisioned the fundamental pr
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Overwhelming to see @LMSAumassmed and UMass Med Spanish still thriving and in good hands years later! 🥹 🇵🇷🇭🇳🇲🇽🇨🇺🇪🇨🇺🇸🇨🇴🇸🇻🇧🇷🇬🇹🇩🇴 VERY grateful for ongoing support from Dr. María García, @UMassDiversity, @LMSA_Northeast, @NHMAmd, @UMassChan.
MD/PhD student Tomás Rodríguez restarted @UMassChan’s Latino Medical Student Association chapter in 2020. He established the optional Medical Spanish elective in collaboration with students from all three schools. #HispanicHeritageMonth @trodriguezUMMS @UMassMDPhD @UMassChanSOM
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Our March 2023 Chapter of the Month is Geisel School of Medicine at Dartmouth! They are hard at work to create a four-year pathway program called Medical Spanish Pathway of Distinction. We would also like to highlight our selected Physician of the Month, Dr. Sonia N. Chimienti!
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Out in @ImmunityCP ! @UMassChan @UMassMDPhD students @nick_d_peterson and @tse_elegans in my lab made a remarkable discovery that fundamentally changes our thinking about a problem we have been studying for years – the ultimate thrill in science! (1/n)
cell.com
Immune sensing of infectious microorganisms is essential for animal health. Peterson and Tse et al. characterize a non-canonical pattern recognition system that intercepts pathogen-derived signals of...
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MD/PhD student Tomás Rodríguez restarted @UMassChan’s Latino Medical Student Association chapter in 2020. He established the optional Medical Spanish elective in collaboration with students from all three schools. #HispanicHeritageMonth @trodriguezUMMS @UMassMDPhD @UMassChanSOM
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Quantification of Genome Editing and Transcriptional Control Capabilities Reveals Hierarchies among Diverse CRISPR/Cas Systems in Human Cells
pubs.acs.org
CRISPR/Cas technologies have revolutionized the ability to redesign genomic information and tailor endogenous gene expression. Nevertheless, the discovery and development of new CRISPR/Cas systems...
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Relaxed targeting rules allow PIWI-clade Argonaute proteins to silence ever-mutating transposons. Our data overturn the common presumption that AGO and PIWI Argonautes follow similar rules for identifying their RNA targets. https://t.co/QJdxSPZdPt
biorxiv.org
In animals, piRNAs direct PIWI-clade Argonaute proteins to slice complementary transposon transcripts. Transposons can evade silencing through target site mutations. We report that PIWIs efficiently...
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#TourDeForcePhDThesisPresentation by @trodriguezUMMS of the @ESontheimerLab
#BravoTomas!!!! with 60 Zoom attendees committee members: @athmapai @job_dekker @xue_lab and Karen Adelman/HMS (#ThanksProfAdelman) @UMassChan @UMassMDPhD
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MD/PhD candidate Jordan Smith is a winner of the Dean's Award for Outstanding Thesis Research. Smith generated the first conditional model of hepatoblastoma, the most common pediatric liver cancer: https://t.co/AokiTsi5nb
#UMassChan2022 @j_leigh_smith @Xue_lab @UMassMDPhD
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