ErikSontheimerLab
@ESontheimerLab
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Lifelong RNA biologist with a lab full of CRISPR pros who are pro-CRISPR and pro-AntiCRISPR @RTI_UMassChan
Worcester, MA
Joined February 2020
RT @RTI_UMassChan: The RTI's Anastasia Khvorova elected to the National Academy of Inventors Fellows Class of 2022!.The new class @AcadofIn….
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RT @LaskerFDN: We wish #LaskerAward winner Victor R. Ambros a happy birthday! By studying the microscopic worm #Celegans, he discovered tha….
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RT @UMassChan: Proud to be at the top in the heart of New England: UMass Chan Medical School is on The Boston Globe’s 2022 list of the Top….
umassmed.edu
UMass Chan Medical School has been named to The Boston Globe’s 2022 list of Top Places to Work in Massachusetts, based on results of an employee survey.
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RT @intelliatx: #HAE News: Today at @ACAAI, Intellia presented additional interim results from its ongoing Phase 1/2 study of NTLA-2002, an….
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This news makes my day 👏👏👏.
Thank you to the HFSP Nakasone award, this is a great honor. Stoked and humbled to be included in the same list as the amazing scientists who received this award in the past.
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Huge congratulations to Professor Watts on this richly deserved promotion! 👏👏🥂.
Ok, so my amazing group (I presume!) foil-wrapped my entire office, and everything in it, to celebrate my just-announced promotion to professor.
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RT @CRISPRjournal: "Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors".Iyer S et al. @ESontheimerLab Scot Wolf….
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I’m joining you on that island. As a reviewer, I’ve always found it as helpful as getting clubbed over the head.
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Take it from me: Tomás rocks.
MD/PhD student Tomás Rodríguez restarted @UMassChan’s Latino Medical Student Association chapter in 2020. He established the optional Medical Spanish elective in collaboration with students from all three schools. #HispanicHeritageMonth @trodriguezUMMS @UMassMDPhD @UMassChanSOM
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🤜🏻🤛🏻.
As @grunewaju notes in his summary, @ESontheimerLab also published similar findings about split prime editors in @NatureBiotech earlier this year: 7/7.
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Great stuff Keith! 👏.
Excited that the latest @JoungLab paper describing split #CRISPR prime editors is out online @NatureBiotech today. This work was led by @grunewaju, Bret Miller, @ReganSzalay with co-authors Peter Cabeceiras, Chris Woodilla @elizajaneholtz @Karl_Petri 1/7.
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🙏.
Please also check out this fantastic @ESontheimerLab paper that was published in NBT recently, describing the "split-PE" discovery (and much more amazing stuff!)
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Great work, Julian, congrats! (And from your previously tweeted photo: nice new digs in Munich 😉).
Boston RT party!🧬So excited about our #CRISPR prime editing work, out @NatureBiotech today – great @JoungLab team work w/ Bret Miller, @ReganSzalay, @johnASeed1, Chris Woodilla, @elizajaneholtz, @Karl_Petri & @JKeithJoung
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Prior fellow from the mid-‘90s! Glad to stay connected.
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RT @somaticediting: 🚨New Publication🚨 from #SCGE PIs @ESontheimerLab and @ScotWolfe1 efficiently uses circular single-stranded #DNA for hom….
liebertpub.com
While genome editing has been revolutionized by the advent of CRISPR-based nucleases, difficulties in achieving efficient, nuclease-mediated, homology-directed repair (HDR) still limit many applica...
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Great stuff Mo, @davidrliu, @_ShannonMMiller and team, congrats!.
4/n We looked to Cas9 orthologs from other organisms as starting points. Nme2Cas9 from N meningitidis stood out. As characterized by @ESontheimerLab & others, this ortholog has natural activity on N4CC PAMs and (bonus for delivery!) is more compact than SpCas9 (1082aa vs 1368aa).
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RT @ColinConine: Check out our overview of strategies to clone and sequence small RNAs which is the cover of this months @Curr_Protocols de….
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RT @NIH_CommonFund: The @somaticediting consortium launched the #SCGEToolkit, a platform housing #data generated from #SCGE studies: novel….
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Thank *you* @ColinConine, this authoritative piece will be very useful for a lot of people! 🙏.
Thank you @aemonten and @Curr_Protocols for a smooth review and making the manuscript significantly better in the process. Also, @ESontheimerLab for inviting us to write it in the first place.
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