Pukkila-Worley Lab is also @rpwlab.bsky.social
@RPWLab
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Research Scientist. Infectious Diseases Physician. Professor of Medicine. UMass Chan Medical School. Innate immunity, intestinal epithelial cells and worms.
Worcester, MA
Joined May 2017
Thrilled to share companion stories from our lab, out today in @ImmunityCP and @CellReports . We characterize an enzymatic TIR protein as an immune sensor in animals. See tweetorial from @UMassChan @UMassMDPhD student @tse_elegans .
Stoked to share our companion stories, now out in @ImmunityCP and @CellReports! We characterize an enzymatic TIR protein as an immune sensor in animals, showing that it is a guard protein in an effector-triggered immune response. 1/.
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Check out the cover of @TrendsImmuno !! Art by lab alumna @tse_elegans to highlight our lab's review in the issue by Khursheed Wani on enzymatic TIR proteins in innate immunity!!!
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Incredibly proud of @Mo_AliNasrallah , a @UMassChan @UMassMDPhD graduate from my lab. So much fun to celebrate his accomplishments and those of his classmates this weekend. #UMassChan2025
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Excited to share another review from the lab, out this week in @TrendsImmuno . Join us for a fun tour of what we think are the coolest proteins in all of innate immunity!
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Excited to share our recent review out in @NatRevImmunol . We discuss mechanisms that identify patterns of pathogenesis -- specific ligands or symptoms in the host that indicate active infection with an infectious microorganism. @UMassChan.
Patterns of pathogenesis in innate immunity: insights from C. elegans
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Absolutely bursting with C. elegans, @UMassChan , @MGHMolBio , Simches 7 pride this morning!!! Congrats Victor and Gary!!!!
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RT @FitzgeraldKate: Looking for an up to date review on dna sensors and their role in autoinflammatory diseases check out this review from….
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Welcome Karthik!!!.
We are super excited to be welcoming @karthik_varanas to the Division of INnate Immunity @UMassChan this November to start his lab @UMassChanPII ---welcome to @UMassChan @UMassChanGSBS #newPI.
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Sharing a nice write-up from @UMassChan highlighting @tse_elegans and her recent companion papers from my lab that were published last week in @ImmunityCP and @CellReports .
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RT @ImmunityCP: Online now: Intestinal immunity in C. elegans is activated by pathogen effector-triggered aggregation of the guard protein….
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SARM - an enzymatic TIR protein. Perhaps the most ancient immune regulator in the Tree of Life and the origins of innate immunity itself. But, is it an immune sensor in animals?.
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RT @MJWu_TW: Join us! My lab @UMassChan is seeking postdocs and research associates who are passionate about how changes in metabolism and….
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RT @farmgirlphd: Kicking off #MAPSS2024 in Madison! Many thanks to the organizers @phillips_lab @RPWLab @TheDouglasLab for all their effort….
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This is SO HUGE!! An incredible story from a super talented graduate student. I have loved watching the story come together at our monthly Innate Immunity Data club. Congratulations @JustKOS1 and @VirulentMind @UMassChanPII is very proud of you both!!.
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A huge and special day for the lab. @nick_d_peterson accomplished so much as an @UMassMDPhD student, culminating in the Chancellor’s award for the top medical student in his class. He is bound for astronomical success as a physician-scientist. I am beyond proud #UMassChan2024
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Chancellor's Award for RPW lab alum @UMassMDPhD student @nick_d_peterson !!! @MGHMedicine is so lucky to have him as an intern!!.
The T.H. Chan School of Medicine Class of 2024 was recognized during the awards breakfast and scholarship ceremony. View the list of honorees, which include Chancellor’s Award winner Nicholas Peterson: #UMassChan2024 @nick_d_peterson @RPWLab @UMassMDPhD
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