Jeremy Luban 🧬🦠🔬🩺🎸🎻
@LubanLab
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Scientist/Professor/Physician/Musician
NYC, Massachusetts
Joined June 2014
@PeaseRoland has this addiction: https://t.co/wkZRciIZRg
bbc.co.uk
Volcanic eruption lights up Iceland.
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LINE-1 is associated with disease and aging. The @RoutLab_RU has uncloaked the core of its key protein, pointing the way towards therapeutic targets. #RockefellerScience
rockefeller.edu
LINE-1 is associated with disease and aging. Rockefeller scientists have uncloaked the core of its key protein, pointing the way towards therapeutic targets.
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No fruit bats are not magic animals that do not suffer disease consequences of bacterial and viral infections (pathology studies like these are very painstaking to perform)
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I couldn't have ended the year with a better gift than to be able to broadly share the main story of my PhD work, recently published in @PNASNews. We found that #PCF11 associates with #WDR82 to silence HIV-1 in latently infected cells. Full article ➡️ https://t.co/9ZwbC5MnO4
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The HUSH complex guards vertebrate genomes from retroelements. Our new structural/biochemical study on MPP8 reveals the interaction interface with TASOR required for HUSH assembly & suggests links between HUSH & SUMO https://t.co/v5caR25yBk
@daniilprigozhin @MedCambridge @MRC_LMB
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Looking for a motivated postdoctoral research scientist with cryo-EM and biochemistry experience to join our group to study virus-host interactions and coevolution. We benefit from a great environment @MRC_LMB @MedCambridge @Cambridge_Uni
https://t.co/SZtK2RLRx3
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Cornell Molecular Biology and Genetics department @CornellMBG has an open call for faculty applicants. Interested candidates please apply. All others please RT. Without a shadow of doubt I have loved it here.
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“Transposable elements contribute to nearly 80% of human-specific candidate cis-regulatory elements in cortical cells” 🧠 …🤯 literally! Amazing dataset 🔥 Congrats to all involved! https://t.co/75JfdawHMc
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🔔'Tis the season...to apply for a new job?! My group @MedCambridge is recruiting for 2 posts: Postdoc: https://t.co/65QjHYDpXk Research assistant: https://t.co/1vSF3py32A Both roles will seek to improve our understanding of coronavirus cross-species transmission. #preparedness
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🔥🔥How does the LINE-1 retrotransposon jump around in the human genome? Super excited to present my postdoctoral work answering this published today @Nature together with twitterless Kathy Collins's lab and @NogalesLab @UCBerkeley
https://t.co/quoQOpZb5X A 🧵
nature.com
Nature - Human LINE-1 ORF2p relies on upstream single-stranded target DNA to position the adjacent duplex in the endonuclease active site for nicking of the longer DNA strand, with a single nick...
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Mucosal antibodies in people with infection, not in vaccinated-only individuals. This is a correlate of protection from infection, although not fully validated https://t.co/VlmC3fu5Io Great work, based on paired nasal and blood sampling
thelancet.com
In summary, we demonstrate that currently available vaccines elicit strong systemic antibody responses, but SARS-CoV-2 infection generates higher titers of binding and neutralizing mucosal antibodi...
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Very excited by our results @Nature showing that IL4R signaling is strongly enriched in myeloid cells that infiltrate mice and lung cancer lesions
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YES! 💯Thanks Massimo and all who helped organize #RetroPath. What a blast it was! A few intense days of amazing 🦠 science in a stunning spot. I’ve learned a ton and made a bunch of new friends! 🥰
A big thanks to our fabulous host Massimo Pizzato of @UniTrento for hosting this year's #RetroPath meeting, it was fabulous!
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A big thanks to our fabulous host Massimo Pizzato of @UniTrento for hosting this year's #RetroPath meeting, it was fabulous!
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Great talk by Hanna-Mari @Baldauf_Lab comparing antiviral activity of Guanyl-binding proteins of 🧒🐭 🐰! GBP2 & GBP5 are some of my fave restriction factors bc both are activated by retroviral LTRs as @SmithaBadarina2 showed nicely before #RetroPath
https://t.co/udHMhWUnce
academic.oup.com
Abstract. Although endogenous retroviruses (ERVs) are known to harbor cis-regulatory elements, their role in modulating cellular immune responses remains p
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My family had to move 4 times in and outside of Gaza City after Israel destroyed their house and they ran out of water . They are now being carpet bombed in Rafah-the very area they were told was safe. When will this end?
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Why HIV-2 infection reduces HIV-1 pathogenesis in dual-infected patients? HIV-2 blocks HIV-1 through a) an interferon response; b) an HIV1-specific block conferred by HIV-2 TAR, suppressing HIV-1 transcription by stalling RNApol II at the promoter https://t.co/FxQH0lxHLr
journals.asm.org
Twenty-five years after the first report that HIV-2 infection can reduce HIV-1-associated pathogenesis in dual-infected patients, the mechanisms are still not well understood. We explored these...
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BREAKING🔔 A new study from G2P-Japan🇯🇵 is out! The preprint will be out so soon, but we first show our results on the efficacy of XBB.1.5 monovalent vaccine - comparison between infection-naïve and XBB-infected individuals. Please retweet/repost🔥 1/
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