Rui Yang 杨睿
@ryangrui
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AI fellow @TexasChildrens, @bcmhouston, Immunologist and Geneticist @casanova_lab and @RockefellerUniv, Peds Trained at @WCMPeds. Opinions are my own.
Houston, TX
Joined June 2013
RT @StuckInStock: $VKTX vs $LLY weight loss drugs comparison (Viking VK2735 vs Lilly Orforglipron) using Ph2 and Ph3 data available https:….
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Mark for next read!.
Very happy to share our review @bloodgenes published today in JHI. We discuss how rare and common genetic variants influence early B cell development and can underlie susceptibility to infectious diseases, autoimmunity and leukemia. 🔬🧬.
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RT @casanova_lab: 1/ We are delighted to share our work published in @SciImmunolgyidentifying the role of LY9 in CD4+ T cell IFN-γ immunity….
science.org
Impaired CD4+ T cell–dependent IFN-γ immunity in humans with LY9 deficiency underlies tuberculosis.
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RT @Tangye_Lab: Congrats to my friend and collaborator JL @casanova_lab. There is no one else on the planet who has contributed so much to….
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RT @casanova_lab: / I was honored to accept the 2025 Novo Nordisk Prize from @novonordiskfond at today’s award ceremony in Copenhagen, Denm….
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RT @BogunovicLab: Thank you for the spotlight. 🙏🏼.Monoallelic expression in human immune cells: linking genotype to phenotype: Trends in Im….
cell.com
Patients with an inborn error of immunity (IEI) often show a complete penetrance of their disease-causing mutation, whereas other forms of IEI show a family pattern where many family members carrying...
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RT @IrisFagniez: I'm running with @FredsTeam to raise money for cancer research at @MSKCancerCenter, and your support would mean so much to….
secure2.convio.net
Fred’s Team is Memorial Sloan Kettering Cancer Center’s (MSK) running program—dedicated to moving us closer to a world without cancer. Participants add more meaning to their miles by running the TCS...
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RT @FilizT_Korkmaz: @WilliamOHa31771 @UnemployedVip @mattyglesias Or shall I clarify. The NIH funds my research. As such, pays for part of….
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RT @JACIInPractice: This comprehensive review article reviews the evidence for and against initiating immunoglobulin replacement therapy in….
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RT @casanova_lab: 1/ I am both delighted and relieved to share my inaugural editorial for the @jhumimmunity.
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The ever-expanding space of IEI. Glad to be part of this community. @IsabelleMeyts @stutangye ❤️ 💪.
The IUIS Inborn Errors Update is online!.
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Thrilled and Honored to part of this work. Congratulations to @MasatoOgishi @casanova_lab @Tangye_Lab, and all authors.
1/ We report @ImmunityCP that the PD-1:PD-L1 axis promotes the development of B-cell memory and antibody responses in mice and humans. To our surprise, the pro-B-cell effect of PD-1 and PD-L1 is, at least partially, mediated in a B-cell-intrinsic manner.
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Thrilled and Honored to part of this work. Congratulations to @MasatoOgishi @casanova_lab @Tangye_Lab, and all authors. Btw, I am losing count how many first authored papers @MasatoOgishi published in a 4y PhD. What a star!!!⭐️⭐️⭐️⭐️ Look forward to more great works from Masato!.
Thrilled to have our paper unravelling impact of impaired PD1 signaling on humoral immunity published in @ImmunityCP. This was a 5y project with collab's near & far 🇦🇺🇺🇸🇫🇷🇯🇵🇨🇦🇹🇷🇶🇦. Thanks to all involved esp @MasatoOgishi @casanova_lab @DrCindyMa @KimLJacobson & Honjo lab!.
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RT @Jonathan_Bohlen: I’m excited to announce our new paper that came out today! The second chapter of my Post-doc @casanova_lab, published….
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Another master piece from @casanova_lab on the discovery of complete IL-7 deficiency. Striking clinical difference between deficiencies of IL-7 and IL-7R, also first described by @anne_puel in 1998. More immunological redundancies and non-redundancies to be discovered via IEI.
1/ I am thrilled to share my main PhD project, conducted at @casanova_lab under the supervision of @anne_puel, just published in @JCI, on autosomal recessive IL-7 deficiency in humans! 🧵👇
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RT @carlosarangof: 1/ I am thrilled to share my main PhD project, conducted at @casanova_lab under the supervision of @anne_puel, just publ….
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RT @stutangye: Great new study from @anne_puel @casanova_lab describing new pts with RELB deficiency. Really thrilled to contributed to thi….
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RT @panhammarstrom: We developed a high-throughput sequencing method to profile immunoglobulin class-switch recombination in human B cells….
journals.aai.org
Key Points. CSR is programmed for deletional recombination in human B cells.The efficiency of c-NHEJ and S region features affects the orientation of CSR i
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What a star! What a bright career ahead for @MasatoOgishi !!!! Congratulations to both @MasatoOgishi and @casanova_lab.
1/ We’re very proud of our PhD grad @MasatoOgishi! A superstar in the lab since 2018, he co-authored >20 papers, including 6 as first/co-first author (so far!). This speaks to the volume of his productivity but also his collaborative spirit and generosity in helping others.
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