Casanova Lab
@casanova_lab
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We're a research lab at Rockefeller University (NY) and Necker Hospital (Paris) studying human genetic and immunological determinants of infectious diseases.
Joined August 2018
1/ We are delighted to share our work published in @SciImmunolgyidentifying the role of LY9 in CD4+ T cell IFN-γ immunity to Mycobacterium tuberculosis.(.
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RT @LASIDimmuno: There is still time to submit your abstract for the upcoming LASID conference! Deadline is July 15th, 2025. Abstracts will….
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RT @HsiehElena: First African Society for Immunodeficiency (ASID) meeting in the books!! So inspired by so many countries coming together t….
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RT @JExpMed: ICYMI: Our Clinical #Immunology Collection feattures recent and exciting advances in the field of translational immunology – n….
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Bravo !.
Here is our latest publication. Somatic PIK3R1 mutations in patients and treatment with alpelisib. Congratulations to the whole team and particularly to two very talented students @morin_gbrl and @Alexandre Garneau🥳🥂🍾.EMBO Molecular Medicine
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RT @HsiehElena: So proud of this work following up on our initial JEM publication of a novel human IEI - dived into underlying mechanisms o….
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RT @jhumimmunity: The editors of the JHI wish you a successful and productive experience at #FOCIS2025 in Boston! 🔍 Explore the complete f….
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RT @ALNeehus: Very happy to share our review @bloodgenes published today in JHI. We discuss how rare and common genetic variants influence….
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RT @HsiehElena: Check out our latest work on the effect of B cell depletion on T cell mediated vaccine response!.
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RT @Lucie_JExpMed: Looking forward to chairing the Late Breaking Abstracts session this afternoon ☀️ If you're attending #FOCIS2025, make s….
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A must-read for anyone interested in human B lymphocytes, their physiology and pathology !.
.@ALNeehus, Neil Romberg, and @bloodgenes review how genetic variation impacts early B cell development, & discuss inherited rare variants & more common polymorphisms that predispose to B cell-related immune disorders & malignancies
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RT @JExpMed: Du, Faz-Lopez, Guery, Barrat et al. describe that TLR7 and TLR8 escape X-chromosome inactivation in plasmacytoid DCs of patien….
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A timely and welcome clarification:.Evaluating IL1RA‐Autoantibodies Across SARS‐CoV‐2‐Related Diseases - Behere - 2025 - Scandinavian Journal of Immunology - Wiley Online Library
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RT @jhumimmunity: Guarnieri, Booth et al. show that topical ruxolitinib induced rapid and sustained improvement of refractory skin #inflamm….
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RT @LASIDimmuno: Autoinflammatory diseases are a big diagnostic and therapeutic challenge so dont miss this webinar!. Sign up for tomorrow….
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An original therapeutic approach:.Immunotherapy as rescue for cardiomyopathy in Omenn syndrome
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RT @jhumimmunity: Boutinaud, Pasquet et al. describe a rare case of infiltrative #cardiomyopathy secondary to Omenn syndrome successfully t….
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RT @joshuamilner2: Super excited about our recent paper describing a high throughput screen for functional variants in the context of APDS.….
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