Petar Scepanovic
@pscepanovic
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Senior Scientist @Roche. Previously Postdoc @Cambridge_Uni, PhD @EPFL and MSc @unito. Microbiome, genomics, PRS, ML, immunology and entrepreneurship.
Basel, Switzerland
Joined October 2014
📢Fully-funded PhD studying the comorbidities of high adiposity. 🔗: https://t.co/8xPwG7eJZH (2 weeks left, due November 20) Great work environment @CAMBRIDGE_CEU @HLRI_Cambridge, collab with @AstraZeneca @MikeXiao_JIANG @CambridgeATS. DM or e-mail for informal enquiries.
Interested in a 4-year PhD studying the genetics of BMI and comorbidities? Don't wait, apply for my @AstraZeneca-funded studentship w/ @MikeXiao_JIANG 🔗: https://t.co/8xPwG7eJZH (due October 31)! @CAMBRIDGE_CEU @HLRI_Cambridge @Cambridgecardio @DPHPC @CambridgeATS
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Out today in @NatureGenet! Important new updates to the Polygenic Score (PGS) Catalog, & a new software tool that simplifies the calculation of polygenic scores in the context of genetic ancestry 👉 https://t.co/0OR1Lw7m0Z
@iamslambert @minouye271 @sritchie73 @Florent_Yvon
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Interested in a 4-year PhD studying the genetics of BMI and comorbidities? Don't wait, apply for my @AstraZeneca-funded studentship w/ @MikeXiao_JIANG 🔗: https://t.co/8xPwG7eJZH (due October 31)! @CAMBRIDGE_CEU @HLRI_Cambridge @Cambridgecardio @DPHPC @CambridgeATS
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Our CEO Marcus Claesson together with @Roche and APC Microbiome just published a study showing changes in the #gutmicrobiome of non-obese mice associated with Type-1 #diabetes and anti-PD-1 #cancer #Immunotherapy
https://t.co/JCpnHzuO1f
#microbiomeanalysis #microbiota
academic.oup.com
ImmunoHorizons is a fully open-access peer-reviewed journal committed to advancing the knowledge of immunology and immunology education.
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I'm delighted to release the first half of my new open-access online textbook in human population genetics: https://t.co/GHMPCTv6BL
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Over and over again, modern behavioral genetics studies have revealed how flawed the assumption of "equal parts nature and nurture" has been. But the myth remains embedded in the conventional wisdom because numbers in the middle feel intuitively "correct".
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One fantastic collaboration with @casanova_lab, @grvsadrian, @ShenYingZhang, and all the co-authors - just go through the thread to discover more !
1/ We are excited to share our report in @JExpMed showing that about 40% of cases of #WestNilevirus (#WNV) encephalitis are due to pre-existing auto-Abs neutralizing type I IFNs, making WNV encephalitis the best understood human infectious disease ( https://t.co/lqug2qZOMT).
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Our latest research on the combined impact of genetics and infection on the risk of cardiovascular disease https://t.co/7UVrMRtR5d
@epflSV @CHUVLausanne
actu.epfl.ch
Researchers at EPFL have found that infection with a common bacterium that is linked to periodontal disease, oral cancers, and bad breath may cause a small increase in the risk of cardiovascular...
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Pls RT! Great opportunity to attend a Summer School exclusively focused on AI & machine learning for healthcare! Offering talks, a mentorship program, student mini-projects, roundtables, networking & an online exhibition. 5-9 Sept. Learn more: https://t.co/U9YT6rznQW
@minouye271
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join me & @EricJCGalvez with the rest of the @Roche's pRED microbiome team in Basel to intertwine human genetics & microbiome! open postdoc position here
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Very pleased to share this exciting new work, a highly collaborative effort, on the development, validation and application of genetic scores for a wide range of multi-omic traits. Preprint: https://t.co/TTH6MV1P7p Online Portal: https://t.co/KTTrt7r8uJ Thread 1/9
biorxiv.org
Genetically predicted levels of multi-omic traits can uncover the molecular underpinnings of common phenotypes in a highly efficient manner. Here, we utilised a large cohort (INTERVAL; N=50,000...
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Pleased to announce our recent work is now live @CellGenomics, in which we show machine learning optimized polygenic scores for blood cell traits can stratify sex-specific trajectories and identify genetic correlations with disease. https://t.co/8q2jwXHb7c Thread 1/8
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Pleased to announce our latest work is now live at Nature Metabolism (@natmetabolism), in which we show polygenic risk scores (PRS) can be used to identify novel and causal proteins underlying disease risk. https://t.co/Re4PnSgwUy Thread 1/9
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Great read on lessons from GWAS on infectious disease phenotypes, by @jacquesfellay @cthorball and @esiborghe.
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We studied microbiome dynamics in 245 FMT cases across 13 studies where fecal transplants were used to treat patients who suffered from rCDI, IBD, Metabolic Syndrome, Drug-Resistant Pathogen colonization, or went through ICI anti-tumor therapy. https://t.co/afA0KoDJF7
Happy to share that the preprint of the last work of my PhD is online 🎉
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Super excited to release https://t.co/CsJaykgnSp, a web application for browsing association results for 3,700 phenotypes across 281,850 individuals from the UK Biobank. The site features plots, tables, and controls for exploring billions of associations.
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Happy to finally share this manuscript - large-scale Crohn's exomes from IIBDGC demonstrates complementarity of GWAS and exome findings and many new CD genes. Unlike neurodev - most signal from more common low-frequency variants
medrxiv.org
Genome-wide association studies (GWAS) have identified hundreds of loci associated with Crohns disease (CD), however, as with all complex diseases, deriving pathogenic mechanisms from these non-cod...
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We're thrilled to release a manuscript on rare variant association testing on the exomes of 300k individuals in the UK Biobank https://t.co/Kgyc9Vk7Nq and a browser of the results:
app.genebass.org
Genebass is a resource of exome-based association statistics, made available to the public. The dataset encompasses 4,529 phenotypes with gene-based and single-variant testing across 394,841 indivi...
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I must admit - Robert De Niro is right: Switzerland is just too perfect, too nice. 😉🇨ðŸ‡ðŸŽ¥ @MySwitzerland_e #IneedSwitzerland #InLoveWithSwitzerland #paidpartnership
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#JobAlert: My group is looking for a talented someone to help us analyze #microbiome data from our #oncology #clinicaltrials
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