michele pagano
@paganolab
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Studying the molecular mechanisms underlying the degradation of cellular regulatory proteins by the ubiquitin system and inform about cancer vulnerabilities
Manhattan, NY
Joined May 2019
now published on line @CellCellPress .
Together with Michele Pagano's lab at NYU, we are excited to share a new story on two F-box protein E3 ligases recognizing two distinct & mutually exclusive degrons encrypted in the quaternary structure of the substrate protein
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RT @CermakLab: Fantastic work by @NikolDibus and an excellent collaboration with Michele Pagano @paganolab and Ondrej Stepanek @AdaptiveImm….
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RT @biorxiv_cellbio: USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination #biorxiv_….
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RT @MickeRzO: I am beyond thrilled to share my first co-first paper. We defined the role of RAD51/BRCA2 in protecting Abasic sites from MRE….
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RT @alessiociulli: Excited to share our latest work combining VHL and CRBN in a single trivalent PROTAC to boost protein degradation. Great….
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RT @nyugrossman: A new study led by researchers at @nyulangone and @Perlmutter_CC identified a gene signature that one day may serve as a b….
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A fireside chat with free thoughts, reflections, and memories.
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RT @CancerResearch: CRI is proud to share the new cohort of Lloyd J. Old STARs! Meet the researchers who will receive $1.25 million over 5….
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RT @YMerbl: I am deeply honored to be named one of this year's recipients of the prestigious Lloyd Old STAR grant of the @CancerResearch .….
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RT @KRHornberger: Next is this related paper from the Winter and Waldmann labs showing a similar phenomenon for IDO1 - and an indicator tha….
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RT @KRHornberger: Double feature today - this first one from @georg_e_winter and colleagues identifies a broad swath of kinase inhibitors t….
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RT @castel_pau: Check out our latest review regarding the biology of RAS GTPase effectors!. It was fun to write this with @AmMozzarelli and….
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RT @nyugrossman: U.S. News & World Report released their latest rankings of hospitals for 2024-2025 and we are excited to share that NYU La….
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Our plasmid collection of 98 human DNA mismatch repair genes and their regulators is now available through @Addgene, together with another >200 plasmids from our lab. We hope they will be useful to the scientific community. see: .
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RT @bvansteensellab: We identified a complex network of proteins that regulate MMEJ:NHEJ repair pathway balance in a chromatin context-depe….
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RT @YKulathu: Branched #ubiquitin has important roles in cell signaling but are very challenging to study due to complexity & lack of tools….
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RT @businolab: 🌟Exciting News!🌟.We are thrilled to share that our recent paper has been published in Nature Communications! Our findings re….
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RT @businolab: Delighted to announce that our postdoctoral fellow, Sehbanul Islam, has been awarded the Rising Star Award from the CHOP Res….
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RT @danetteldaniels: So, so honored to be included in this group of such inspiring scientists!.
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