Our Nature Communications paper is out! We present CaliAli 🧠—a MATLAB toolbox for aligning & extracting neurons across 1p imaging sessions. Tracks signals across months using vasculature-based alignment. Open-source & documented. Paper:

Just updated CaliAli—a toolkit for longitudinal tracking in calcium imaging. It now auto-chunks each session; set your desired frames-per-batch and let it handle the rest. No manual file splitting, no RAM bottlenecks. https://t.co/Mrz9uYkx8j

🚨 Our Nature Communications paper is out! We show that fear memory formation is supported by reactivating just a few adult-born neurons during REM sleep. 🧠💭 📖 [ https://t.co/oyGEidSM0q] #Neuroscience #Sleep #Memory

Just updated CaliAli — a tool for tracking neurons in 1p calcium imaging across sessions 💾 Now with low-memory mode: split large sessions to process data even when single files don’t fit in RAM https://t.co/Mrz9uYjZiL Having trouble? Feel free to reach out — I reply weekly.

Today in @ScienceMagazine we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells, a collaboration with @SternbergLab. 1/13 https://t.co/ZLHtZm5Gmw

自転車「ながらスマホ」反則金1万2000円　26年4月から導入 https://t.co/Gq9bemEB0F

Kudos to my former PI @masanorisaka !

Silent Synapses in the Adult Brain "review current evidence for silent synapses in the adult brain and explore the potential roles of these highly plastic structures." https://t.co/u4BIiQSo6w

Thrilled to visit Rene’s lab! We had insightful discussions with great minds. Pablo’s CaliAli 1-P calcium imaging analysis tool garnered significant attention. Wrapped up with a fantastic American dinner alongside Rene’s wonderful team @Rene_Hen @pabloivg

Pablo and I had a wonderful time discussing science with Denise and her team, followed by a tasty Mexican lunch. Excited for future collaborations! Big thanks to Paul for helping make this meeting happen!🌮🧠 @ko3600 @denisejcai @pabloivg @Franklandlab

Check out our latest paper. Here we attempted to bridge levels of analysis in memory research, linking receptors, dendritic spines, higher-order neuronal dynamics and behavior in mice. @NatureNeuro https://t.co/Gnq2AeVy95 1/

(1/5) Attention, Cellular Imaging Enthusiasts! Thrilled to share that our Analysis "The Multi-modality Cell Segmentation Challenge: Towards Universal Solutions" has been published in Nature Methods (@NatureMethods) 🎉🎉🎉 Cell segmentation is a critical component of

Check out our new paper on feeding in Nature Communications 🔥! Along the way we answer a question that has puzzled philosophers for centuries: Does activation of periaqueductal gray (PAG) vgat cells make mice follow ping-pong balls? https://t.co/CFdM6I7f6N

The eyes are windows to…the hypothalamus. Final cut now featuring locus coeruleus

My first ever first author paper and PhD work is out in @SfNJournals ’ #JNeurosci! In this paper, we’ve discovered a new neuronal circuit governing sleep/wake behavior. 1/10 https://t.co/eBgkeS3Rr0

𝗜𝗳 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻 𝗶𝘀 𝗮 𝗰𝗼𝗺𝗽𝗹𝗲𝘅 𝘀𝘆𝘀𝘁𝗲𝗺 𝗮𝗿𝗲 𝗼𝗽𝘁𝗼𝗴𝗲𝗻𝗲𝘁𝗶𝗰 𝗺𝗮𝗻𝗶𝗽𝘂𝗹𝗮𝘁𝗶𝗼𝗻𝘀 𝗰𝗮𝘂𝘀𝗮𝗹? https://t.co/hteImqFK72

CaliAli shines in complex scenarios & outperforms other methods in precision, sensitivity, & stability. Whether studying representational drift, remote memory, neuron development, or multi-trial behavior, CaliAli is the tool to go! 🌟 Find #matlab code:

Using a modified #miniscope with flexible light inputs @sakthivelsbio, we've paired optogenetics with calcium imaging to accurately identify tracked neurons.

This innovative tool goes beyond traditional algorithms by integrating blood vessel (BV) 🩸info for accurate alignment🎯. The result? We've achieved continuous neuron tracking in every single one of the 20 recording sessions spread over an entire month! 🔄🔬 2/4.

🧪🧠 Our latest #neuroscience paper presents #CaliAli, a game-changing neuron-tracking tool for one-photon calcium imaging! CaliAli excels at detecting weak signals & maximizes the number of trackable neurons. 🚀💡 @masanorisaka. 1/4 https://t.co/jXh4b8OIYP