Laurent Nguyen
@neuroliege
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Scientific director and PI at GIGA Institute, University of Liège 🇧🇪 - personal views
Liege, Belgium
Joined March 2018
🎉 Happy to share our latest work! Congratulations for the fantastic achievement @fanny_lepiemme @CarlaGSilva1 @miriam_jt @StouffletJ with help from @MazzuGabi
science.org
During mouse development, migrating cortical interneurons get steered away from blood vessels.
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New preprint showing human brain organoids from our library of patient #IPSCs modeling neurodevelopmental disorders. Four major clinical classes of NDDs (MIC, EPI, PMG, ID) showed distinct scRNAseq and organoid phenotypes. https://t.co/uMlxxGmo0O
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Intercellular communication in the brain through a dendritic nanotubular network | Science
science.org
Intercellular nanotubular networks mediate material exchange, but their existence in neurons remains to be explored in detail. We identified long, thin dendritic filopodia forming direct dendrite–d...
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Human brain organoids record the passage of time over multiple years in culture | bioRxiv
biorxiv.org
The human brain develops and matures over an exceptionally prolonged period of time that spans nearly two decades of life. Processes that govern species-specific aspects of human postnatal brain...
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@neuroliege is redefining how we think about Mechanotransduction shapes distinctpatterns of neuron migration during cerebral cortex development. #cellmech2025
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🧠 Our new study is out in Nature Communications! DNMT1 regulates the migration of cortical interneurons, with implications for cortical layering and function — and potentially neuropsychiatric conditions. 🔗 https://t.co/ChAL3z1Yx0 Huge thanks to the amazing team/collaborators!
nature.com
Nature Communications - The function of DNMT1 (DNA methyltransferase 1) in these subsets of immature, migrating cortical inhibitory interneurons is not fully understood. This study shows that DNMT1...
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Our latest work is out today in @ScienceMagazine: a self-organizing system that models organizer-driven patterning and commissural axon guidance in human neural development. This was achieved with human midline #assembloids by combining floor plate and spinal cord #organoids
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10/10 Here’s the paper @CellCellPress if you want to dig in https://t.co/R94qlCglm6 That’s it. Thanks for sharing! @dev_neuro @MRC_CNDD @KingsIoPPN @wellcometrust
cell.com
Neuronal activity triggers PGC-1α-mediated transcriptional programs that drive the late maturation of PV+ interneurons, essential for cortical circuit function. PGC-1α partners with ERRγ and Mef2c to...
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We are hiring! Interested in infection biology, immunology, microbiology? Funded postdoctoral position in our lab at Institut Pasteur https://t.co/o9YjMzBbC6
https://t.co/Y9FAQzXxFj
@institutpasteur
@Inserm Contact us at postdoc.biu@pasteur.fr
research.pasteur.fr
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🚨 We are thrilled to announce our amazing list of keynote speakers!! @PCusachs
@GeorgHalder
@hirashima0203
@dagmarIber
@johannaivaska
@gijsjekoenderi1
@neuroliege
@renkawitzteam
@Sixt_Lab
@VickySanzMoreno Kit Parker @EdouardHannezo
@creinhartking
@WickstromLab
@MEmilieTerret
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The Sensory Transduction and Nociception Group @painchannels at @NeuroAlc offers a 1-year (extendable to 3) postdoctoral position. The call is open until position is filled. More info 👇 https://t.co/IxvAnKqOYp
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It was such a pleasure to visit the Institute and catch up with colleagues and friends! Thank you for the invite @BorrellLab
Today Dr. Laurent Nguyen @neuroliege from @GIGA_ULiege (@UniversiteLiege) offered us a fantastic #SeminarsIN about how prenatal alcohol exposure impairs the cerebral cortex. Great talk, thank you! 👏👏👏
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Today Dr. Laurent Nguyen @neuroliege from @GIGA_ULiege (@UniversiteLiege) offered us a fantastic #SeminarsIN about how prenatal alcohol exposure impairs the cerebral cortex. Great talk, thank you! 👏👏👏
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We have the pleasure of welcoming Dr Laurent Nguyen @neuroliege from @GIGA_ULiege (@UniversiteLiege) next Friday at #SeminarsIN 🙌 He is an expert in molecular mechanisms of brain development in health and disease. Don’t miss it! @BorrellLab
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Check our new results showing that loss of Elongator activity impairs the maturation tempo of ependymal cells bioRxiv
biorxiv.org
Conditional deletion of Elp3 in the mouse forebrain leads to microcephaly at birth. In this study, we demonstrate that these mice also develop postnatal hydrocephalus, associated with an enlargement...
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A Postdoctoral Research Associate post is available in the lab in Human Organoid Neurobiology and ALS/MND Research - see our job advert in Nature Careers https://t.co/c7gGJ2WgRh
nature.com
A Postdoctoral Research Associate position is available for 2 years in human 3D organoid-based disease modelling in Amyotrophic Lateral Sclerosis (...
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Rapid and quantitative functional interrogation of human enhancer variant activity in live mice | Nature Communications
nature.com
Nature Communications - Here the authors introduce a CRISPR-based, dual-fluorescent reporter system in mice, which enables rapid in vivo testing of the effects of human non-coding variants linked...
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Svante Paäbo has been made Honoris Causa doctor of the University of Liège. Followed by a geeat meeting with him at GIGA on this occasion @GIGA_ULiege @UniversiteLiege @frsFNRS
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Join us at the Institut Pasteur! Experience the magic of the Pasteur Quadrant—where groundbreaking basic research meets real-world applications. Don't miss this opportunity! Check out the call below 👇 https://t.co/7QJoW9zEJd
research.pasteur.fr
The Institut Pasteur launches an international call to recruit new junior research group leaders in the application of cutting-edge transdisciplinary approaches to the exploration of host-microbe,...
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Staff position available in my lab at Stanford! Please share. Details below 👇
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Our 2024 CSHL conference on human brain development and stem cell models is in full swing, with over 300 participants! This year’s event features exciting new discoveries and dynamic discussions, driven largely by the energy & insights of trainees. A privilege to organize this
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