Geraldine Zimmer-Bensch
@BenschZimmer
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Professor for Neuroepigentics, investigating #DNAmethylation, #histoneModifications, #lncRNA in cortical development and aging, neuronal function, #degeneration
RWTH Aachen University
Joined January 2020
Today in @Nature we report a new prime editing strategy that can rescue a common cause of many genetic diseases in a disease-agnostic manner. This approach converts a redundant endogenous tRNA into an optimized suppressor tRNA, enabling a single prime edit to rescue premature
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Excited to share that our new preprint is out, showing PV function linked to glial states by DNMT1. "DNMT1 Coordinates PV Interneuron–Glia Coupling to Maintain Cortical Network Stability and Regulate Behavior." https://t.co/b9szDSwxtA.
biorxiv.org
Parvalbumin (PV) interneurons are central to cortical network stability and psychiatric vulnerability. Here, we identify DNA methyltransferase 1 (DNMT1) as a key epigenetic regulator linking PV...
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We’re hiring! @RWTH is opening a W3 Full Professor position in Stress Resilience of Plants 🌿 Join a strong research environment with excellent facilities & great colleagues in the Faculty of Maths & Natural Sciences. Please share & spread the word!
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Honored to see our work featured among the Editors’ Highlights in the “From brain to behaviour” collection at @NatureComms! 🧩 DNMT1-mediated regulation of somatostatin-positive interneuron migration impacts cortical architecture and function ➡️
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👩🎓🇩🇪👨🎓 Ready to advance your academic career? PhDGermany offers a wide array of open doctoral positions in various disciplines. Dive in, explore your options, and make your mark in the world of research 👉
daad.de
Want to do your PhD in Germany? Find currently offered positions in this database
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What if the DNA methylation enzyme DNMT1 isn’t just about DNA? Our new preprint reveals a cytosolic role for DNMT1 as a scaffold controlling neuronal morphology via DOCK7–Rac1/STMN1 signaling & mitochondrial trafficking. A paradigm shift in DNMT1 biology!
biorxiv.org
Proteins traditionally confined to a single cellular compartment are increasingly recognized to exert non-canonical functions in alternative domains. The DNA methyltransferase 1 (DNMT1), classically...
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BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has
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This week on the Nature Careers Podcast: How having too rigid a plan could result in exciting opportunities passing you by. https://t.co/kIJIDZl61r
nature.com
Nature - Having too rigid a plan could result in exciting opportunities passing you by, warns Ottoline Leyser.
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By popular demand — the next edition of our hands-on @Stanford @BrOrganogenesis course is coming in 2026! This year, the focus turns to neural #assembloids, reflecting the growing movement toward modeling circuit-level and complex cell-cell interactions in brain disease. The
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🚀 The RWTH Center for Computational Life Sciences (CCLS) brings together AI, modeling & biology to decode life’s complexity. Explore how data-driven research is shaping the future of health & sustainability Watch the video 👉 https://t.co/KpyYWqoIos
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Today: Seminar on: Addressing Neurodegenerative Diseases in Support of SDG 3: Good Health and Wellbeing: Recent Advances in Alzheimer’s and Other Neurodegeneration Research
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On Wednesday, October 8, join the Springer Nature SDG3 Good-Health and Wellbeing on "Addressing Neurodegenerative Diseases in Support of SDG 3: Good Health and Wellbeing: Recent Advances in Alzheimer’s and Other Neurodegeneration Research". Learn more: https://t.co/RRM0QSluU8
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🚨 NRW Return Programme 2026: Up to €1.25M over 5 years to establish your own independent research group in the Life Sciences (e.g. neurobiology). 👉 More details: https://t.co/KvcSRA4zkY A great opportunity – also here in Aachen! 🌍🧬
mkw.nrw
Mit dem Rückkehrprogramm will das Ministerium für Kultur und Wissenschaft junge Wissenschaftlerinnen und Wissenschaftler zur Rückkehr nach Nordrhein-Westfalen bewegen.
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Deadline is close!
🌍 Open Call! RWTH Aachen University invites postdocs from outside the EU to apply for the “Port to Europe” Fellowship (24 months funding, all disciplines). Start your research journey at one of Europe’s top universities! 🚀 Deadline: Oct 5, 2025. 👉 https://t.co/12zK86kfVB
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Open Call @embl 📍 Heidelberg 🧬 Postdoc position (3 yrs) – Computational Biology Join a world-leading research environment & drive cutting-edge data-driven biology! 🔗 Apply here: https://t.co/vbzFetIrcS
#ComputationalBiology #EMBL
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LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development
cell.com
Adami et al. demonstrate that evolutionarily young L1s are expressed in human pluripotent stem cells and are dynamically regulated throughout neural differentiation. The study examines the role of...
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Online now: Microglia regulate neuronal activity via structural remodeling of astrocytes https://t.co/EcEoFCmtUJ
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A time-lapse film offers a glimpse of a hidden milestone of human development: the moment when the newly formed embryo latches onto the uterine lining. Watch a human embryo implant itself — with brute force https://t.co/dkXCZsV10B
nature.com
Nature - Video provides an up-close look at a human embryo plunging into tissue that simulates the uterine lining.
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Join @LenPennacchio, @ZhipingWeng, @xielablife, me and all speakers in beautiful Suzhou, China for this year's CSH Asia Systems Biology of Gene Regulation & Genome Editing meeting, Oct 20-24. Let's bring the international communities together! Abstract deadline Sept 5! More infos
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🌍 Open Call! RWTH Aachen University invites postdocs from outside the EU to apply for the “Port to Europe” Fellowship (24 months funding, all disciplines). Start your research journey at one of Europe’s top universities! 🚀 Deadline: Oct 5, 2025. 👉 https://t.co/12zK86kfVB
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