Mel Symeonides Profile
Mel Symeonides

@msymeonides

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Following
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Assistant Prof at the University of Vermont, interested in HIV latency, syncytia, placenta etc. Opinions = my own. @msymeonides.bsky.social

Burlington, VT
Joined November 2008
Don't wanna be here? Send us removal request.
@VermontGreenFC
Vermont Green FC
4 months
VERMONT GREEN ARE DIVISION CHAMPS! ๐Ÿ† THE UNBEATEN BOYS IN GREEN CLAIM THE FIRST TITLE IN CLUB HISTORY. VERMONT, THIS ONEโ€™S FOR YOU!ย  MERCI LES VERTS! ๐Ÿ’š
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@msymeonides
Mel Symeonides
1 year
This feels desperate but does anyone happen to have a full-length sequence for the HIV-R7/E-/GFP vector, the one that's in J-Lat cells?
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@msymeonides
Mel Symeonides
1 year
WOW this looks amazing
@GrayCampLab
Gray Camp
1 year
Intestinal Immuno-Organoids (IIOs): Striking differences between immune cells in the blood or resident in the intestine which are maintained in vitro! Implications for T-Cell Bispecific and other therapy? @Nature @EricTopol @Roche @IHB_Research https://t.co/x6YWSjl8yp
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@msymeonides
Mel Symeonides
1 year
And major props to @embojournal for publishing it!
@RenaudPoincloux
Renaud Poincloux
1 year
Our work on ERM proteins in macrophage migration and cortex mechanics is out in the EMBO Journal ๐ŸŽ‰ https://t.co/W9QeqX2pN2 Great review process by @ReviewCommons ๐Ÿ™ And here is a thread on this story: https://t.co/bckCHvUd52
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@msymeonides
Mel Symeonides
1 year
Great work! Now imagine a scenario where this was the first time anyone had looked at the role of ERMs in migration in any cell type... Negative data, probably not worth publishing, right? Wrong! Publish "negative data"!
@RenaudPoincloux
Renaud Poincloux
2 years
We are excited to announce that our latest paper on macrophage migration and the cortex of these amazing cells is now available on @bioRxiv. https://t.co/v62x8yVrxs Thread 1/ ๐Ÿ‘‡
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@msymeonides
Mel Symeonides
1 year
As in, a mole. WHAT
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@msymeonides
Mel Symeonides
1 year
Found deceased mole in our crawlspace. The smell was unbelievable. It tried to dig a tunnel through the insulation to get out. A MOLE.
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@msymeonides
Mel Symeonides
1 year
AI reply guy bots. SMH
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@JSalogiannis
John Salogiannis
1 year
Happy to share our lab's first preprint! We found that ER tubules hitchhike on Rab6-marked vesicles. Proud of grad student @a_m_langley, lab tech @AbelingSarah and undergrad Erinn Wagner @uvmcmb @UVMLarnerMed
@biorxiv_cellbio
bioRxiv Cell Biology
1 year
Movement of the endoplasmic reticulum is driven by multiple classes of vesicles marked by Rab-GTPases https://t.co/6i4C93vZem #biorxiv_cellbio
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@MicrobiomDigest
Elisabeth Bik
2 years
I'm going to start a new hashtag to show cases where universities or journals have been notified of severe (image) concerns years ago, but have not taken any action. I will name and shame, because it's frustrating and maddening. #IntegrityInertia
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@LongDesertTrain
Ryan Hisner
2 years
@SolidEvidence Key comment in the paper: "To date, we have not encountered any cases with persistent SARS-CoV-2 infection that has not responded to tailored antiviral treatment after recognition of the condition." Chronic infections can be cured & should be a public health priority.
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@msymeonides
Mel Symeonides
2 years
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@msymeonides
Mel Symeonides
2 years
Not sure about the biological relevance of this finding given that CD4 T cells basically seem to not do this... But very interesting and a very well thought-out series of controls! One more reason to be wary of Jurkat and THP-1 cells...
@LabWaggoner
Waggoner Lab
2 years
Retroviral genomes are translated after entry, challenging the notion that retroviruses require reverse transcription to produce viral proteins, which has significant implications for basic retrovirology, immune responses and gene therapy applications https://t.co/E6Y4aHVGks
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@LabWaggoner
Waggoner Lab
2 years
Retroviral genomes are translated after entry, challenging the notion that retroviruses require reverse transcription to produce viral proteins, which has significant implications for basic retrovirology, immune responses and gene therapy applications https://t.co/E6Y4aHVGks
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@euforna
Eugenio F. Fornasiero
2 years
Are you a cell biologist interested in nanoscale fluorescence imaging? Check out our new review @TrendsCellBio https://t.co/XTXSj4IVBf Thanks and kudos to all authors: @ElisaDEste @AndImaging @RLincolnChemist @FelipeOpaz_o #dye #imaging #nanoscopy #superresolution
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@SolidEvidence
Marc Johnson
2 years
This is nothing like the BA.1 or Delta waves. Both of those lineages were the dominant lineage in the state within 2-3 weeks of arriving with immediate spikes in wastewater numbers. 3/
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@msymeonides
Mel Symeonides
2 years
If you're still on here trying to have reasoned discussions and exchange meaningful information, yikes.
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@SolidEvidence
Marc Johnson
2 years
Do you think you've had long-term GI problems since having Covid? We are performing a study examining the characteristics of viruses, specifically persistent SARS-CoV-2 infections, in stool samples. 1/3
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@msymeonides
Mel Symeonides
2 years
There's a garbage paper going around claiming detection of vaccine spike in the circulation 6 months after vaccination... it's nonsense and is by the same guy who claimed (and is selling a book saying) that SARS2 is a bacteriophage. Enough said.
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@msymeonides
Mel Symeonides
2 years
So cool.
@Sixt_Lab
Sixt Lab
2 years
๐Ÿงต(1/6) How do immune cells know where to go? It has been proposed that cells simply respond to externally established gradients of chemokines, but we think thatโ€™s not allโ€ฆ
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