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Official account of the National Center for Biotechnology Information at @NLM_NIH . Privacy: | Website help: info @ncbi .nlm.nih.gov
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NCBI Hidden Markov Models (HMM) Release 13.0 is now available! This release has 16,143 HMMs and 315 new HMMs since release 12.0. Learn more:
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RefSeq prokaryotic genomes and proteins are now annotated with Gene Ontology (GO) terms! Learn more:
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Get rapid access to
#Wuhan
#coronavirus
sequence data and analytics. Newly-released GenBank data available here:
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Get rapid access to
#Wuhan
#coronavirus
sequence data from the current outbreak as it becomes available. We will continue to update the page with newly released data.
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NCBI will use ANI analysis to correct existing public records in GenBank. This will ensure that taxonomic information on genome assemblies is as accurate as possible.
The latest post on NCBI Insights explains how we’ll correct these records.
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Introducing the Comparative Genome Viewer (CGV)! The CGV is an easy-to-use visualization tool that helps you quickly compare eukaryotic genome assemblies and identify genomic changes that may be significant to biology and evolution. Learn more:
#NCBICGR
0
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Happy
#DNADay2023
! Join us in celebrating the 20th anniversary of the Human Genome Project’s completion and the 70th anniversary of the discovery of the DNA double helix. Learn all about DNA Day:
0
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The first complete sequence of a human genome, known as T2T-CHM13, is now available! Finding the new assembly at NCBI is easy. More info here:
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BLAST+ 2.8.1 is released with new databases and better performance
2
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The latest version of BLAST+ is now available and includes two exciting new features! You can now run searches faster and focus your searches by organism more easily. More info:
#NCBIBLAST
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#NCBIBLAST
+ 2.14.0 now with faster protein and translated searches. You can search nr over 20% more quickly and smaller databases up to 3 times faster. More details 👉
0
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BLAST+ 2.13.0 now available with SRA BLAST, ARM Linux executables, and database metadata!
#NCBIBLAST
0
23
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The first complete genome sequence of the current monkeypox virus outbreak is now available in GenBank. Learn more:
1
35
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We are happy to announce a new version of the stand-alone Prokaryotic Genome Annotation Pipeline (PGAP)! Learn about the new features and updates here:
0
15
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GenBank Release 248.0 is now available! This release has 17.11 trillion bases and 2.62 billion records. Since the last release, 52,784 records were updated. Learn more:
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#COVID19
is an emerging, rapidly evolving situation. Learn about the basics like symptoms & what to do if you are sick; and see the latest info from
@CDCgov
on
#NIH
’s page:
#coronavirus
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We are excited to announce a new feature in the Multiple Sequence Alignment (MSA) Viewer! You can now search the anchor or consensus sequence of a multiple alignment for short sequence strings. Learn more here:
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Primer-BLAST can now design primers for a group of related target sequences!
0
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NCBI hidden Markov models (HMM) release 4.0 now available! This release contains 17,443 models, including 94 new models since the last release. Read more:
0
14
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The latest version of the BLAST databases lets you:
1. Limit your search by taxonomy using information built into the BLAST databases
2. Search sequences by accession faster
3. Use blastdbcmd to retrieve sequences by taxonomy from a BLAST database
#bioinformatics
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Download Hidden Markov models (HMMs) release 15.0! This release contains 16,667 HMMs, including 279 new HMMs since release 14.0. Learn more:
0
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#NCBIBLAST
+ 2.14.1 now available with improved documentation, faster and more reliable database downloads, and some bug fixes. More info and download:
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NIH’s Sequence Read Archive (SRA) will be freely accessible through Amazon's Open Data Sponsorship Program! Read more:
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APPLY NOW for our virtual workshop, “An Update on NCBI
#BLAST
and Other Sequence Analysis Tools”!
#SciEd
#Bioinformatics
0
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Announcing the SARS-CoV-2 Variant Calling Pipeline! This new analysis pipeline can uniformly process raw sequence data produced by various sequencing platforms. Learn more 👉
3
14
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New to finding NCBI
#data
? Join our workshop, An Introduction to Pathogen Data at NCBI, to learn how to best access
#microbial
&
#pathogen
data! More info here 👇
#SciEd
#BioInformatics
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A new version of the Prokaryotic Genome Annotation Pipeline (PGAP) is available! This release includes structural and functional annotation improvements and bug fixes. Learn more:
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NCBI Pathogen Detection now contains over one million isolate genomes from 48 organism groups: 47 bacterial, and one fungal!
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#SARS
-CoV-2 sequence data is essential in the fight against the
#COVID19
pandemic. Submit your sequence data to the INSDC (GenBank
@NCBI
, ENA
@emblebi
, and DDBJ
@DDBJ_topics
) to support and maintain rapid
#OpenAcess
to these crucial data
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Coming soon! Beginning in the first week of January 2023, NCBI Taxonomy will initiate changes to prokaryote phylum names. Learn more:
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We have updated the Prokaryotic representative genome collection, which includes over 900 new species! Learn more:
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Wow! Thanks! We'll keep working to make sure that BLAST is a useful, powerful, essential bioinformatics tool.
The most important piece of software/software suite ever written for structural bioinformatics is:
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Check out GenBank release 260.0, now available on the NCBI FTP site. This release has 31.18 trillion bases and 4.46 billion records! Learn more:
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Now available! HMM Release 11.0 contains 15,643 models. Learn more 👉
0
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💻 New
#Codeathon
Opportunity! We are teaming up with the National Institute of Allergy and Infectious Diseases to host a Beyond Phylogenies Visualizations Codeathon. Apply today! 👇
#Bioinformatics
#CodingLife
#Networking
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Apply to our virtual workshop, "Using NCBI’s Primer-BLAST to Design & Analyze PCR Primers" by May 23rd! Learn more here:
#SciEd
#BLAST
#Bioinformatics
#PrimerDesign
0
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Release 12.0 of the NCBI protein profile Hidden Markov models (HMMs) used by the Prokaryotic Genome Annotation Pipeline (PGAP) is now available! Check out what's new 👇
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Prokaryotic Genome Annotation Pipeline (PGAP) now produces files suitable for submission to GenBank!
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📣 Last chance to apply for our
#virtual
workshop, An Introduction to Pathogen Data at NCBI. Learn how to access
#microbial
&
#pathogen
data!
#SciEd
#BioInformatics
0
14
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Release 14.0 of the NCBI protein profile Hidden Markov models (HMMs) used by the Prokaryotic Genome Annotation Pipeline (PGAP) is now available. The release has 252 new HMMs since release 13.0. Download it today!
0
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Need genomic sequence and annotation data for a eukaryotic organism? Now you can easily gather that data from across NCBI with Datasets!
Read more about the new resource on NCBI Insights and give it a try today.
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We reannotated over 1,000 Streptomyces genomes! Read more on NCBI Insights:
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Next week, NLM will launch a pilot project to test the viability of making preprints—scholarly manuscripts posted by the author(s) to openly accessible platforms, usually before peer review— resulting from NIH-funded research available via PubMed Central.
0
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New ribosomal RNA BLAST databases available on the web BLAST service and for download
0
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The updated NCBI Datasets Genomes page now has genome data for all domains of life, including bacterial and viral genomes! Check out the new filters and actions available in the genomes table:
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Looking for genomes for SARS-CoV-2 variants? NCBI now supports searches for SARS-CoV-2 variant names such as B.1.1.7, B.1.351, or P.1. Learn more:
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NCBI is excited to introduce Pebblescout, a pilot web search service that quickly finds matches in very large next-gen nucleotide databases. Check out our preprint for more details:
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Applications are open for our virtual workshop, "Getting Started with NCBI Data in
#Python
"! Apply by Nov. 21st!
#SciEd
#Bioinformatics
0
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Get the latest release of Magic-BLAST (1.6.0), NCBI's next-gen alignment tool. Now with usage reporting, access to SRA in the cloud, taxids in SAM output, file upload of SRA accessions and more!
#NCBIBLAST
#NCBImagicBLAST
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Download NCBI's
#Prokaryotic
#GenomeAnnotation
Pipeline (PGAP) and run it on your own machine, a compute farm, or in the
#Cloud
on your own data!
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32
Did you know you can download and run the Prokaryotic Genome Annotation Pipeline on your own machine or in the cloud?
Give it a try and send us your thoughts!
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NEW PubMed proximity search feature! Combine a phrase search and a proximity search in the same query using Boolean operators, such as AND, OR, NOT. Here is an example:
0
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GenBank Release 253.0 is now available. Since the last release, we added one trillion bases and 150 million records! Learn more 👉
0
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There is still time to apply for our virtual workshop, "An Introduction to NCBI Cloud Computing for Biologists"! More info here 👇💻☁️
#CloudComputing
#SciEd
#GradChat
#Bioinformatics
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The BLAST programs and databases are available in Docker and cloud-ready!
0
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Do you want to learn how to use Primer-BLAST to design specific primers for PCR? Check out our upcoming workshop on September 26! Application deadline is September 12. More info:
#NCBIBLAST
0
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31
Today is
#WorldTuberculosisDay
. NCBI supports tuberculosis research by tracking antimicrobial resistance in Mycobacterium tuberculosis. Check it out:
#EndTB
0
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Conserved Domain Database (CDD) version 3.20 is now live! Version 3.20 contains 1,614 new or updated NCBI/CDD-curated domains. Learn more here 🔗
#NCBICGR
#Bioinformatics
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NCBI is now producing a new set of taxonomy files that include the taxonomic lineage of taxa, information on type strains and material, and host information.
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We are updating influenza virus names to reflect changes to the International Code of Virus Classification and Nomenclature (ICVCN). Name changes will take effect this summer! Learn more 👉
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Get programmatic access to NCBI gene and sequence data through Datasets command-line tool and API!
0
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📣Attention biology students! Did you know NCBI has free resources and tools to help you find and download data for your research projects? Check out this example, looking at the sequence and structure of the TP53 gene in the domestic cat:
1
8
29
Test server for the PubMed API (E-utilities) is now available! We will be moving to an updated version of the E-utilities API for PubMed in June 2022. Don’t wait until launch! Try the test server and provide feedback. Learn more here:
0
6
29
Applications for our virtual workshop, "An Introduction to NCBI Cloud Computing for Biologists" are OPEN NOW! More info here 👇
#CloudComputing
#SciEd
#GradChat
#Bioinformatics
0
8
27
Do you use NCBI Datasets APIs and command-line tools to access and download genomic data? As part of our ongoing effort to enhance your experience, we are making significant updates in the coming months. Learn more:
1
5
29
New release of the Read Assembly and Annotation Pipeline Tool (RAPT), now 2X faster!
0
10
29
RefSeq Release 212 is available and contains the first new annotation of human in four years! It also contains new annotations for 29 species, including: gray squirrel, American grasshopper, and fishing cat. Read more:
0
10
29
A more modern PubMed Central (PMC) is coming - let us know what you think in PMC Labs!
3
13
28
Ever gone virus hunting? If so, we need your help! Join us at the SoCal
#Bioinformatics
Hackathon! We’ll upload known & novel viruses from >100K datasets to the cloud. You’ll code and problem-solve to ID them.
Apply here (deadline - December 12 3pm PT):
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22
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We are excited to launch a beta version of RAPT, the Read assembly and Annotation Pipeline Tool, a one-step application for the genome assembly and gene annotation of archaeal and bacterial isolates. Learn more here:
0
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An updated bacterial and archaeal reference genome collection is available! A total of 497 species are included in this collection for the first time and 174 species are represented by a better assembly. Learn more:
0
10
27
Next month, we’ll be at
@ucsc
for a pangenomics in the cloud
#hackathon
!
Apply today:
More info:
#bioinformatics
2
16
24
An updated bacterial and archaeal representative genomes collection is available! A total of 610 species are represented for the first time. Learn more 👇
1
11
27
Join us for our virtual workshop, "Identifying Clinically Relevant Genes in Bacterial Genomes"! Applications are now open:
#SciEd
0
6
27
1
8
27
Read the new publication on AMRFinder, a tool that identifies resistance genes in pathogen genomes!
0
13
26
RefSeq release 82 contains the complete reannotation of prokaryotic genomes, including E.coli & salmonella
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