BioNTech SE
@BioNTech_Group
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Our vision is to harness the power of the immune system to translate science into survival $BNTX
Mainz, Germany
Joined November 2018
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Bye bye Europe, hello Africa! The containers for our 1st BioNTainer just arrived in Kigali after a bit more than 24 hours of traveling by truck and plane. Thank you to H.E. President
@PaulKagame
, his ministers and teams as well as honorable guests.
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We are honored that our co-founders Dr. Ugur Sahin and Dr. Özlem Türeci are featured on the cover of
@TIME
this week. The accompanying article provides an inside look at BioNTech, our peers, and the science behind the COVID-19 vaccines developed around the world.
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We’re honored to have welcomed our African partners for the first time on the African continent as construction began for the initial African
#mRNA
manufacturing facility in Kigali, Rwanda, 4 months after we introduced the
#BioNTainer
concept in February.
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The six containers comprising our
#BioNTainer
for our first planned manufacturing facility in Africa were produced in Europe, underwent quality checks and are being prepared for shipment to Kigali, Rwanda, where they are expected to arrive in Q1 2023.
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Congratulations to Ugur Sahin & Özlem Türeci for having been awarded the Order of Merit of the Federal Republic of Germany by President Frank-Walter Steinmeier & Chancellor Angela Merkel. The award shows the difference that innovation and science can make.
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We today announced signing an MoU with the UK government to accelerate trials for personalized
#mRNA
#immunotherapies
. Our objective: providing personalized cancer therapies for up to 10k patients by end 2030 in clinical trials or as authorized treatments.
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Invited by the
@KenupFoundation
, President
@PaulKagame
of Rwanda, President
@Macky_Sall
of Senegal, &
@EU_Commission
President
@vonderleyen
met
#BioNTech
CEO Uğur Şahin to discuss the establishment of vaccine manufacturing capabilities in the AU.
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All 27 EU Member States received their first batches of our
#COVID19
vaccine. The picture below shows a couple of them. What a great day!
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We've reached a new milestone: We've manufactured 1bn doses of our
#mRNA
based
#Covid19
vaccine together with our partner
@Pfizer
. Our teams go above & beyond every day to bring the vaccine to as many people as possible around the world. Kudos to our colleagues!
#TeamBioNTech
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We began manufacturing
#mRNA
at our site in Marburg: one mRNA batch is enough to produce approx. 8 mio doses. We will submit production data to EMA in the upcoming weeks for final validation of the Marburg site in order to start supply in April.
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At a high-level meeting in Marburg we introduced a turnkey
#mRNA
manufacturing solution called
#BioNTainer
for scalable vaccine production in Africa. We are working with our country partners&
@WHO
,
@AfricaCDC
, AMA and
@EU_Commission
to establish end-to-end manufacturing network
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The
@EU_Commission
granted Conditional Marketing Authorization for our
#mRNA
#COVID19
for all 27 member states. For us, this marks the end of an extraordinary year & gives hope that we may be able to return to some sense of normalcy in 2021.
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Our colleague, Özlem Türeci, who is deeply rooted in science, accepted a professorship for “Personalized Immunotherapy” at
@uni_mainz_eng
Medical Center and the Helmholtz Institute for Translational Oncology (HI-TRON Mainz). Congratulations, Özlem!
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This week, the first vaccines manufactured in Marburg will be distributed to various European countries! What does one of the largest COVID-19 production facilities in Europe look like? Here is “where the magic happens”
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We are strengthening our manufacturing capabilities in Marburg, Germany, with a EUR 40m investment: We have finished construction of our first in-house plasmid DNA manufacturing facility. German Chancellor
@Bundeskanzler
@OlafScholz
visited the site today.
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Our researchers found that the sera of BNT162 trial participants inhibited pseudovirus bearing the UK strain SARS-CoV-2 spike in a neutralization range that is regarded as biologically equivalent to the unmutated SARS-CoV-2 spike. More in
@FT
’s article
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Today, the German regulatory authority, the
@PEI_Germany
, approved the Phase 1/2 clinical trial for our
#vaccine
program to prevent
#COVID19
infection. More about the milestone in our global development program in collaboration with
@pfizer
& Fosun Pharma:
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Our first manufacturing partner within the African Union has just been announced!
@biovac_inst
is a Cape Town based biopharmaceutical company which will support the production of more than 100m doses of our
#COVID19
vaccine as well as the distribution.
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+++ Omicron BA.4/BA.5 vaccine update +++ The FDA today granted Emergency Use Authorization (EUA) of a 30-µg booster dose of our Omicron BA.4/BA.5 bivalent vaccine, as a booster for individuals ages 12 years and older.
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The recent flood disaster in Germany has a dramatic effect on a large number of people who've lost relatives, friends and homes. In solidarity, we will be donating 1 million € to the German Alliance for Disaster Relief (Aktionsbündnis Katastrophenhilfe).
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To our
#Twitter
community: Please note there are no personal accounts being run by our executives. We are already in contact with
@Twitter
and
@TwitterSupport
to delete all personal accounts related
#UgurSahin
and
#OezlemTuereci
.
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We are pleased to have had H.E.
@PaulKagame
visiting our
#BioNTech
headquarters in Mainz. It was an honor to provide an impression of our cutting-edge technologies and scientific work happening in our labs every day. We share the goal of bringing novel medicines to
#Africa
.
I had the great opportunity to visit with Uğur Şahin at
@BioNTech_Group
facility in Mainz, Germany. Impressive innovations in biotech!
#HighLevelStuff
. A very good person and couple he and Dr. Özlem Türeci are!
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We have published updated
#COVID19
vaccine data supporting efficacy and safety in children from 6 months through 4 years of age. The updated analysis showed 73.2% vaccine efficacy and a favorable safety profile.
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We are excited to welcome the latest addition to the BioNTech family: our colleagues in Marburg. The tech transfer is currently being made and we plan to start the production of potential
#COVID19
vaccines in 2021. Welcome to
#TeamBioNTech
!
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We want to help eradicate Malaria. Therefore, we’re launching a project aimed and developing a well-tolerated and highly effective Malaria vaccine and implement sustainable vaccine supply solutions on the African continent.
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你好Nǐ hǎo from China! This week we participated in
@ciieonline
to showcase our
#mRNA
technology and how we aim to leverage it for individualized cancer medicine and a potential COVID-19 vaccine. A big thank you to our partner
@Fosun_Intl
for having us!
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We want to revolutionize cancer treatment and we continue to advance our pipeline: the first patient has been treated in our BNT111 randomized Phase 2 trial. BNT111 is the lead product candidate from our proprietary FixVac platform.
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We and our partner
@pfizer
completed the regulatory submission for our
#Omicron
BA.4/BA.5-adapted bivalent
#COVID19vaccine
for children 5-11 years of age to
@EMA_News
- only a few days after the submission to
@US_FDA
.
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We’re excited to announce our plans to establish our first regional hub in
#AsiaPacific
region & 1st
#mRNA
manufacturing facility in
#Singapore
– expanding our ability to manufacture & deliver
#mRNA
vaccines & potential therapies to people around the world
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Our
#COVID19
vaccine is 91.3% efficacious 7 days through up to 6 months after the 2nd dose. Results are based on 46,307 trial participants (>12k received the vaccine 6 months ago) demonstrating strong protection.
The
@Pfizer
-
@BioNTech_Group
vaccine protects against symptomatic Covid-19 for at least six months and is highly effective against the South African variant, according to new findings released by the companies via
@WSJ
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Based on our knowledge about the mechanisms behind the
#Covid19
vaccine & the biology of tested variants, we believe immunized people would have a high level of protection against severe disease even if infected by Omicron, writes
@bopanc
about his talk with Ugur Sahin in
@WSJ
.
Don’t panic: The Omicron variant could lead to more infections among vaccinated people but they will most likely remain protected from a severe course of illness, according to the
@BioNTech_Group
co-founder
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We’re excited to be in
@TIME
’s first 100 Most Influential Companies list. This honors the hard work of our
#TeamBioNTech
&
@Pfizer
colleagues, who went above & beyond to develop & manufacture our
#mRNA
COVID-19 vaccine in light speed.
#TIME100Companies
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We welcomed
@TIME
to our site in Marburg for a unique behind-the-scenes look at all steps involved in manufacturing our
#mRNA
based
#COVID19
vaccine. We are so proud of our
#teamBioNTech
whose hard work has contributed to a global solution. The video shows some of our heroes.
Inside the facilities making the world's most prevalent COVID-19 vaccine
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“mRNA could be the next revolution in the biopharmaceutical landscape” said one of our co-founders Ugur Sahin and Özlem Türeci who joined
@TEDChris
for a
#tedmonterey
talk about
#COVID19
. Learn more about our
#mRNA
technology and what’s next.
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mRNA approach to target malaria: Today, we announced the initiation of a first-in-human Phase 1 study with BNT165b1, the first candidate from our BNT165 program for the development of a multi-antigen malaria vaccine candidate.
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We want to help to bring this pandemic to an end. In light of the
#DeltaVariant
, we have early added a new pillar to our comprehensive
#COVID19
booster strategy – keeping us ahead of the COVID-19 virus.
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Today, we have announced that the first subject was dosed in a first-in-human Phase 1 clinical trial with BNT163, a prophylactic herpes simplex virus 2 vaccine candidate. The program is part of our collaboration with the
@Penn
.
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The
@EU_Commission
expanded the conditional marketing authorization for our
#COVID19
vaccine to incl. individuals 12-15rys of age. Our pediatric studies evaluating the safety & efficacy of our vaccine in children from the ages of 6mths - 11yrs are ongoing.
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We are saddened by the loss of many lives in Türkiye and Syria. The humanitarian situation across Ukraine also remains dire. We are thankful for the first responders and will donate €500,000 each to Aktionsbündnis Katastrophenhilfe and
@unoflucht
.
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Today we announced the acquisition of a manufacturing facility in Marburg, Germany. The site, which should be fully operational in H1 2021, will have an annual production capacity of 750 million doses of our promising
#COVID19
BNT162b2
#VaccineCandidate
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Together with the
@deutschesmuseum
, we revealed a brand-new exhibition piece: The bioreactor we used to produce the first dose ever of our
#COVID19
vaccine. We are honored to have a piece of us be presented alongside notable other objects that have been pivotal to human welfare.
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BioNTech SE supports humanitarian aid for the people of Ukraine with a donation of one million Euro to the nonprofit organization for refugee relief ‘UNO-Flüchtlingshilfe’ – the partner of UN Refugee Agency (UNHCR) in Germany.
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Creating the foundation today to address challenges of tomorrow: we’re evaluating a 3rd dose of our
#COVID19
vaccine against current & new variants. We’re also discussing regulatory pathways similar to that of the flu vaccine to adapt vaccines if needed.
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We applaud
@kkariko
and Drew Weissman on their
#NobelPrize
in Physiology or Medicine for pioneering nucleoside base modifications which were one of the key innovations applied to our
#mRNA
-based COVID-19 vaccine. Gratulálunk and congrats!
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We, together with
@instadeepai
, have developed an Early Warning System as a new computational method detecting high risk
#SARS
-CoV-2 variants. In trial period, the system identified >90% of
@WHO
designated variants 2mths before their official designation.
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Today, we especially celebrate all of our female co-workers: With over 54% female colleagues and 45% women in leadership roles, we’re proud to challenge the status quo in which women are still a minority in
#science
and
#leadership
positions!
#IWD2021
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We announced positive data on the safety, tolerability & immunogenicity of 2 Omicron-adapted vaccine candidates (mono- & bivalent). Preliminary lab studies showed both candidates neutralizing Omicron BA.4 and BA.5 though to a lesser extent than for BA.1.
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We aim to strengthen the “tech” in BioNTech with our agreement to acquire
@instadeepai
to support our strategy to build world leading capabilities in
#AI
- and
#ML
-driven
#drugdiscovery
and development of next-generation immunotherapies and vaccines.
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We announced the signing of a letter of intent with Brazilian biopharmaceutical company Eurofarma Laboratórios to manufacture our
#COVID
-19 vaccine for distribution within Latin America. This is an important step to broaden the access to vaccines.
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Addressing a pandemic requires global collaboration. As part of our pledge of 2bn doses to broaden access to our
#COVID12
vaccine, we’re providing 500m doses at a not-for profit price to the US for donation to ≈100 low- & lower middle-income countries.
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#Tokyo2020
オリンピック・パラリンピック競技大会の参加選手と代表団に、新型コロナウイルスのワクチンを無償提供することを誇りに思います。このような特別なイベントへの支援機会を提供してくれた
@iocmedia
に感謝します。
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We plan to supply the EU with up to 1.8b additional doses of our
#COVID19
vaccine & entered a new agreement with the
@EU_Commission
to supply 900m doses of our COVID-19 vaccine to the EU, with an option to request up to an additional 900m doses.
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Q1 updates: we delivered > 450m doses of our COVID-19 vaccine globally. We’ll further optimize our technologies and expand our pipeline as we meet our ambition to become a global, fully-integrated immunotherapy company.
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We are proud to provide doses of our
#COVID19
vaccine to help vaccinate athletes & delegations in the Olympic & Paralympic Games
#Tokyo2020
. We thank the
@iocmedia
for the opportunity to support this extraordinary event in these times.
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2021 was a year of historic impact that
#BioNTech
has had on global health. We expect 2022 to be a year of tremendous expansion and a once in a generation opportunity to transform medicine. Our aim: to harness the power of the immune system to fight human diseases.
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Preliminary Ph1 data from our and
@Genentech
’s individualized
#mRNA
based cancer vaccine program (BNT122 in our pipeline) presented at
#ASCO22
. The data in patients with pancreatic cancer showed a favorable safety profile & was highly immunogenic in 8/16.
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We initiated a rolling submission to
@EMA_News
for our
#COVID19
#vaccine
candidate BNT162b2.
#CHMP
will now start reviewing pre-clinical data, while BNT162b2 will remain subject to
#EMA
’s diligent standards for quality, safety and efficacy.
📢 EMA's human medicines committee (
#CHMP
) starts the
#RollingReview
of a 2nd
#COVID19vaccine
:
👉
#COVID19
#UnitedAgainstCorona
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We celebrated
#TeamBioNTech
at our virtual Christmas party. Our colleagues received a meal kit to cook dinner with at home while watching a few colleagues who cooked live in a studio. Thank you to Özlem, Sierk, Jens and Ryan who were rockin’ around the pots and pans!
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