Kevin Bassler
@kevin_bassler
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Happy to see this paper finally out from our very 1st PhD student @K1_joo @eLife 🥳Big thanks to all lab members & collaborators! @LabSchlitzer @red_ven @LabSchultze @haohuang_0086 @MakdissiNikola @norabalzer1 @kevin_bassler and many more X-less people!
elifesciences.org
Identification of distinct yolk sac-derived macrophage subpopulations in the fetal liver reveals their crucial role in shaping the hematopoietic niche, impacting erythropoiesis and granulopoiesis...
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Today #CZCellxGene is releasing the R package cellxgene.census — it gives access from R to Census, the largest standardized aggregation of single-cell data, composed of 33M+ cells and 60K genes. You can easily export slices to Seurat or @Bioconductor. 🧵⬇️ https://t.co/Wcirm7C2ZY
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The definition of chutzpah: Talk about the importance of removing gender bias from algorithms. Advise 19 graduate students all of whom are men.
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The ability to score cells for good marker genes is most helpful for scRNA-seq cell type annotation. Here are three resources. Further development is warranted 🟣 PanglaoDB https://t.co/JhIXYi66gp 🟡 CellMarker https://t.co/CAqR4pU4k9 🟢 ABC portal
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Spatial-omics goes 3D🤗! Out at Cell @CellCellPress 👉🏼 We developed DISCO-MS with @labs_mann, a spatial proteomics technology for specimens fully imaged in 3D. DISCO-MS is aided by robotics and enables the study of diseases at their early stages. https://t.co/MyvXnnBDgL🧵👇
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Check out our latest work, “Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state” 💊🔮 https://t.co/nvhbsitfvm.
elifesciences.org
Combined analyses of transcriptome and chromatin accessibility elucidated the mechanisms underlying cancer cell lines response to antitumor candidates and provided a versatile perturbation-informed...
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Alveolar #macrophages in early stage COPD show functional deviations with properties of #impaired #immune #activation @FrontImmunol @LabSchultze #ThieleLab @UniBonn
https://t.co/0113rigVv5
#TGF-β1; #blood; #macrophage; #monocyte
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cellpypes - cell type pipes for R. Annotate scRNAseq data manually with simple rules:
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Fast and highly sensitive full-length single-cell RNA sequencing using FLASH-seq | Nature Biotechnology
nature.com
Nature Biotechnology - FLASH-seq speeds up high-sensitivity scRNA-seq while sparing resources.
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#phdposition #openposition #academia #womenshealth #femsci We have an open PhD position at @LabSchultze, Bonn, Germany! 🤩 Join the #Femmunity research team and investigate the female #immunesystem during the #menstrualcycle ♀ More details here >>> https://t.co/uJbOcxoCiC
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CAREER FAIR ANNOUNCEMENT Dr. Kevin Bassler @kevin_bassler is the founder of @AimedAnalytics, a data analysis start-up, that was recently awarded the EXIST grant and is now on the way to become a GmbH. In #Neurizons2022, he will talk about what founding a start-up entails!
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With AI to individual patient care: Medical start-up project at the University of Bonn receives EXIST start-up grant. Congratulations! Read more: https://t.co/KyYoyn7thU
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#SARSCoV2 beeinflusst Fresszellen so, dass sie vll Vernarbung der Lunge befeuern. Das könnte eine Ursache sein, warum Patient*innen mit schwerem #COVID19 langwierige Therapie brauchen. @ChariteBerlin @Helmholtz_HIRI @RWTH @SelbachLab @Sander_Lab @AE_Saliba
https://t.co/Y19uEzPiyU
mdc-berlin.de
Bei schwerem COVID-19 vernarbt die Lunge meist außergewöhnlich stark, zeigen Forscher*innen aus Berlin, Aachen und Würzburg im Fachjournal „Cell“. Zentral sind dabei Fresszellen des Immunsystems. Die...
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The finding: single-cell analysis reveals detrimental effects of insomnia on immune cells. The irony: the main cause of my insomnia is single-cell analysis https://t.co/IkC0fOqWmC
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Very excited to see another manuscript successfully applying Swarm Learning to medical data
biorxiv.org
Artificial Intelligence (AI) can extract clinically actionable information from medical image data. In cancer histopathology, AI can be used to predict the presence of molecular alterations directly...
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Wondering how many cells, reads and samples you need for your next #scRNA-seq experiment? Check out scPower by @heinig_matthias lab, just out @NatureComms. General finding: more cells, less reads! https://t.co/qRcPrQFz5Z
https://t.co/q23toLLtG9
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I'm hiring! R/Tidyverse fluent? Experience with Shiny, Docker, bioinformatics, git, DBs? Join a growing and distributed team of data scientists and bioinformaticians with remote work flexibility in lovely Charlottesville, VA!
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📢Join the lab! We are looking for a Postdoc in bioinformatics working within the @WGGC_de and a Phd in computational biology to work with state-of-the-art NGS data! PLEASE RT!
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