Jonah Cool
@JCoolScience
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Cell biologist, geneticist and fascinated by all things science 🦠 🔬 . @CZIScience program officer leading single cell tech & supporting @humancellatlas
California, USA
Joined July 2017
Train and submit your model predictions for the OpenADMET Expansion challenge!! Lots of submissions already rolling in. Check out the webinar from @wpwalters, @barrybunin @huggingface et al for more info
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Today @AnthropicAI released PubMed integration for Claude. No hallucinations. Just real science, real data. As a beta tester, this has been a game changer—like having a supercharged research assistant. Here are 6 prompts that will transform how you search the literature. A 🧵
We’re building tools to support research in the life sciences, from early discovery through to commercialization. With Claude for Life Sciences, we’ve added connectors to scientific tools, Skills, and new partnerships to make Claude more useful for scientific work.
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A scientist's guide to AI agents — how could they help your research? @Nature 👉 https://t.co/qpS2J6hfav Enjoyed discussing this with @LizzieGibney. Great to see @ScientistTools featured, along with several ongoing projects in our group. AI agents can accelerate discovery, but
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Deadline extended to May 25! ⏳Consider submitting your recent work to the Generative AI and Biology workshop at @icmlconf
⏰ Deadline extended to May 25th for GenAI and Biology workshop, considering multiple requests & NeurIPS deadline! 🚀Recent submissions to NeurIPS & other conferences/journals are welcome! 🧬For amazing speakers and more details:
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It’s time again for Cell Biology at Scale (CB@S), an annual gathering for researchers from diverse disciplines to share ideas on how new technologies can transform #cellbiology! Co-hosted by #CZBiohubNY & @ChanZuckerberg. Learn more and register: https://t.co/JleiackGKO
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1/ The Chan Zuckerberg Initiative @cziscience is now hosting our AIDO.Cell-100M in its virtual cells platform. 🧬🦠
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Big Network news! #CZBiohubSF + #CZImagingInstitute will join forces to form a new Biohub aimed at developing groundbreaking imaging technologies to observe, measure, and understand biology like never before. Learn more: https://t.co/2ZGoG78IU4
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It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis
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Very excited about this project as a model for partnership, opportunity to open up new fields of biology, and the provide critical data that advance models toward fundamental questions in cell biology. Stay tuned for progress!!!
“The Billion Cells Project will help clarify our understanding of the fundamental biology underpinning human health + disease while supercharging efforts at the intersection of AI & biology.” - @JCoolScience Learn more about the project https://t.co/YaP800otuT
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CZI recently announced an innovative new opportunity for GPU access. It's an exciting approach specifically aimed at supporting bold and ambitious problems that are bottlenecked on compute. Have a look and please apply or encourage others to do so!
chanzuckerberg.com
Apply to build large-scale AI/ML models using compute power on CZI’s high-performance computing cluster to power new approaches to biological discovery.
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6/6 the future is 😎. Like great science efforts, the questions and technology opportunities outpace the immediate learnings. Looking across our grantee communities and internal roadmaps has me filled with excitement. Can't wait for the next waves of data, tech & models.
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5/6 the papers in the package on ethics and equity shared a lot of work and thinking on best practices that can be generalized. More focus on engagement and inclusion are necessary for robust science and paving the way for future collaboration models.
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4/6related to the 👆point on computational tools, I'm proud of the work supported by data curation and data access via @cellxgene and the variety of papers that contribute to or draw on that data. Supporting science with grants & software brought me to @czi - this is a 🙌example!
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3/6 data is important for first drafts but so too are computational tools that enable utility of the incredible data resources. It was cool to see progress on the computational side represented so robustly in this early work.
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2/6it has been such a pleasure working with the team at @cziscience to support HCA. The breadth of work is a great reminder of all the pieces necessary to progress toward useful atlases. Contributions from CZI projects and the wider community demonstrate that it takes a village.
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The @humancellatlas package in @Nature is a bright spot for me as we move toward the end of the year. I'm late to the party and really enjoyed watching all the buzz last week🎆! Congrats to all involved👏 The weekend allowed reflection on a few personal areas of excitement 🧵1/6
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Pleased to share that our #earlyAIR cross-tissue, age-specific, #flowcytometry reference of immune cells from five tissues of the pediatric #airway is now published in @jacionline. https://t.co/GQLQaSt2Y5
@cziscience @MCRI_for_kids @UniMelbMDHS @RCHMelbourne
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Incredibly exciting and important work. Studies like this are pushing the limits of functional screen and absolutely represent a beacon for work in the years to come. Can't wait! Also, the liver is amazing:)
In collaboration with Reuben Saunders, @JswLab, and Xiaowei Zhuang, we are very excited to release Perturb-Multi: a platform for pooled multimodal genetic screens in intact mammalian tissue. Check it out! https://t.co/iJ8hi3ddz4
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In collaboration with Reuben Saunders, @JswLab, and Xiaowei Zhuang, we are very excited to release Perturb-Multi: a platform for pooled multimodal genetic screens in intact mammalian tissue. Check it out! https://t.co/iJ8hi3ddz4
biorxiv.org
Organ function requires coordinated activities of thousands of genes in distinct, spatially organized cell types. Understanding the basis of emergent tissue function requires approaches to dissect...
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Interested in #singlecell and #spatial #metabolomics ? Then book your calendar for December 10th! – Our online, free event will summarize major achievements of the field in 2024. #metabolism #omics #MALDI #EPFL With @Gio_Dangel0 lab we prepared a fantastic lineup. 🧵 1/5
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