Kashish Jain
@kashish195
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Postdoc @UCSF, PhD student @ MBI Singapore, 👨‍🔬 @ IIT Kanpur (he/him)
San Francisco, CA
Joined January 2015
RT @NCBS_Bangalore: 📢 1st Annual Indian Mechanobiology Meeting. 📆 15-16 October 2025.📍@ncbs_bangalore. 🔗 ⌛ Deadline….
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RT @AjayTijore: 2nd paper from Mechanobiologics Lab is out in Journal 'Small' @AdvPortfolio. This work led by my 1st PhD student Alka. Supe….
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RT @natrevbioeng: In celebration of International Women In Engineering Day 🚀 @INWED1919 #INWED25 #WomenInSTEM today we highlight articles b….
nature.com
Nature Reviews Bioengineering - Integrating bioprinting with organoid technology can enhance tissue engineering by improving complexity, reproducibility and scalability. This Review discusses...
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RT @NatureMaterials: Epithelial cell-cell contact resistance to mechanical stress is defined by a regulated viscous dissipation through the….
nature.com
Nature Materials - Epithelial cell–cell contact resistance to mechanical stress is defined by a regulated viscous dissipation through the cytoskeleton, where the toughness of the cell...
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RT @LuizaJarovsky: 🚨 New study reveals that when used to summarize scientific research, generative AI is nearly five times LESS accurate th….
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RT @CellCellPress: In the latest issue! Cell membranes sustain phospholipid imbalance via cholesterol asymmetry
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RT @johannaivaska: @IvaskaLab @midibu.bsky.social uncovers FUNCTIONAL role for TNS1 condensates as reservoirs of inactive adhesion protei….
biorxiv.org
Integrin adhesion complexes mediate cell-extracellular matrix (ECM) interactions and undergo dynamic remodelling to regulate cell adhesion and migration. Here, we demonstrate that tensin 1 (TNS1), a...
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RT @LammerdingLab: How do altered levels of lamins and other nuclear envelope proteins contribute to cancer metastasis, and how does this r….
nature.com
npj Biological Physics and Mechanics - Nuclear envelope proteins, mechanotransduction, and their contribution to breast cancer progression
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RT @NatureBiotech: The identification of novel targets together with technological advances is transforming our ability to effectively modu….
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RT @biorxiv_cellbio: Optogenetic control of mechanotransduction based on light-induced homodimerization of talin #b….
biorxiv.org
Integrin-based cell adhesions (IACs) serve as primary sites where piconewton-scale actomyosin-generated mechanical forces are transmitted to the extracellular matrix (ECM), generating traction forces...
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RT @BSBEIITK1: Are you interested in neuroscience and neuroengineering? If so, don't miss out on this great opportunity at @BSBEIITK1 on 3r….
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🚀Exciting new review exploring the intersection of #mechanobiology & #AI!.From predicting cell forces to analyzing complex genomic data, AI is unlocking new insights into how cells respond to mechanical cues.
nature.com
npj Biological Physics and Mechanics - Exploring the intersection of mechanobiology and artificial intelligence
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RT @Hallou_Lab: 🚨 Paper Alert 🚨 .Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" in @naturemethods👇!!.htt….
nature.com
Nature Methods - The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic...
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Thrilled to be part of the Damon Runyon community and to receive this funding. It really helps a lot in these uncertain times! Thank you to my mentor Dr. Valerie Weaver for her unwavering support!.@UCSFHospitals.
We are delighted to announce our most recent class of Damon Runyon Fellows! These 13 scientists will receive four years of independent funding to investigate cancer causes, mechanisms, therapies, and prevention. Read more:
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RT @JungmannLab: ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬. The glycocalyx, our cells' sugar coat, holds secrets in immunolo….
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RT @ahcells: The @ConfinementLab is hiring! If you are interested in doing a #postdoc at the @MBIsg in science-friendly #Singapore, please….
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RT @Aiims1742: Interesting preclinical study that makes you wonder how much of the “stromal mutations” in cancer are just translocated muta….
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👉By forming STARnodes, integrins ensure signaling is sensitive, robust, and rapidly adaptable. These hubs are critical for intracellular signal relay and response, and are modulayed by phosphorylation and de-phosphorylation events at the adhesions.
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👉Our study reveals that integrin STARnodes seed signaling by clustering phosphorylated FAK and other proteins, responding dynamically to external cues like force and geometry.
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