Our latest paper has just been published in Cell! https://t.co/5iAl1EaGEJ We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.

Undoubtedly one of the most exciting and I think, potentially far-ranging technologies we have ever developed. TRANCERs: turn an enhancer into a promoter with the same specificity as the enhancer! A promoter for all occasions!

@ketanpatelimmo1 @AGoriely @RDMOxford @AdamMead_Oxford @d_dcruzh @vyas_lab @l_cmurphy @beth_psaila In the 2nd scientific session of the day, chaired by @jojdavies, three PhD students are battling it out to win the Ita Askonas Medal and a £500 prize! 🏅💸   Good luck to all three finalists, @lizthescientis1 (Rehwinkel Group), @IsaacSWalton (@Wilkie_Lab) and @josephhamley98

It was wonderful to see the Seminar Room so busy yesterday for our Student Presentation Day! Congratulations to everyone who presented, especially @lizthescientis1 (Rehwinkel Group), @IsaacSWalton (@Wilkie_Lab) and @josephhamley98 (@jdavieslab) who have been shortlisted for the

We are looking for an RA to join the lab to work on a fantastic genomics project! https://t.co/mSBLNhGCp1 Closing date next week! Please RT - thank you!

Very happy and honored to present our work from my postdoc project in @DaanNoordermeer lab @I2BCParisSaclay on CTCF clustering at TAD boundaries and the novel multi-contact 3C assay: Nano-C – now published @NatureComms. https://t.co/6l1d6ID0PL. A nice 🧵 written by Daan 👇

Our work from my master’s project exploring cytosine base editors for gene editing in Drosophila is now published @ScienceAdvances (my first first-authorship🎉) https://t.co/hdiDCcYbyP There are several additions since the preprint, so read along for a 🧵with the main points:

It is fantastic to finally be able to see this paper in print, great collaboration with everyone: https://t.co/8uYefyX6gf MLL-AF4 creates high density enhancer interactions by recruiting a transcription complex including FACT and PAF

Buckle up! We're in for a wild ride today. A new @NatMetabolism paper by scientists from China adds a surprising twist to the long-known FTO GWAS story. The FTO locus (16q12.2) is the first ever GWAS locus to be associated with obesity and even after 16 yrs now, scientists

Multiplex-genome architecture mapping (multiplex-GAM) facilitates rapid, unbiased and ligation-free determination of chromatin interactions, as compared to Hi-C. @apombo1 @RobBeagrie @anto_scial @LonnieRWelch @LabPombo @helmholtz_de https://t.co/eyfVaNuzZA

In 2016 I looked after a girl who died during a transplant for HbE beta-thalassaemia. I am overwhelmingly pleased that we have been able to correct HbE with near 100% efficiency using base editors. https://t.co/LIVpGvJPhR Brilliant work from Mohsin Badat @Montytrench @jdavieslab

Excited to present our in-depth protocol for Micro Capture-C, published in @NatureProtocols . This innovative method achieves 3C data generation at base pair resolution level! 🧬🎉 @josephhamley98 @jojdavies @jdavieslab @MRC_WIMM

@MRC_MHU @MRC_WIMM @Oxford_MRC_DTP

Really pleased to see our @NatureProtocols paper out this week. We have put together a comprehensive guide to generating base resolution 3C data! @hangpengli578 @jojdavies @jdavieslab

Congratulations @josephhamley98 and @hangpengli578 for putting together a nature protocols paper for Micro Capture-C!

Really pleased to share the detailed protocol for Micro Capture-C in nature protocols. It is capable of generating 3C data down to base pair resolution. @jdavieslab @hangpengli578 @josephhamley98 @MRC_MHU @MRC_WIMM https://t.co/DidcL1xReq

Preprint online: In my master’s project with @crisprflydesign @Boutroslab, we explored base editors to improve gene inactivation in multicellular organisms, using the crowd favourite #Drosophila. A 🧵about temperature, deaminases, and a missing UNG 👇 https://t.co/oXm0igCRHj

Our newest paper with many great collaborators including @andiroy and @SiobhanRice12 : PAF1 and FACT cooperate with MLL-AF4 to drive enhancer activity in leukemia https://t.co/IYewTfDcIr

Our latest work online @nature — Compatibility rules of human enhancer and promoter sequences Do enhancers prefer certain promoter sequences? Thread 👇 Way to go @dtbergman @thouis and team!

Really excited to share our latest paper... fantastic collaboration with @MariekeOudelaar where we developed tiled Micro Capture-C to generate Hi-C like plots at 20bp resolution. Turns out there are nanoscale TADs inside enhancers! https://t.co/hHIWnQFLnM