I2BC Paris-Saclay
@I2BCParisSaclay
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I2BC is a world-leading institute in the field of Molecular and Cellular Biology, Biochemistry, Microbiology and Virology
Gif-sur-Yvette, Paris (France)
Joined April 2017
L’I2BC quitte Twitter. Retrouvez-nous sur Bluesky @i2bcparissaclay.bsky.social pour suivre nos actualités scientifiques @CEAParisSaclay,@CNRSbiologie,@UnivParisSaclay.
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The structure of a Tau fragment bound to tubulin prompts new hypotheses on Tau .mechanism and oligomerization | @scoopit
scoop.it
We have identified a novel tubulin surface targeted by the Tau protein. From these results, we formulate new hypotheses on the regulation of microtubules by Tau and on Tau oligomerization. Tau is a...
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Portrait Jeune Chercheur – Christopher Dane Fage, Chercheur en biochimie structurale | @scoopit via @LifeSciencesUPS
scoop.it
Christopher Dane Fage is a structural biochemist who, in January of 2024, joined the Institute for Integrative Biology of the Cell - I2BC (CNRS/CEA/UPSaclay, Gif-sur-Yvette) as a CNRS CRCN to lead...
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Perylene-derivative singlet exciton fission in water solution | @scoopit
scoop.it
Ultrafast formation of triplet statates by singlet fission in water solution. We provide evidence that singlet fission—a process where one excited state splits into two—can occur in water-soluble...
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Bioorthogonal monomycolate of trehalose disclosed the O-mycoloylation of mycoloyltransferases and other cell envelope proteins in C. glutamicum | @scoopit
scoop.it
Discovering the mycoloylome of Corynebacterium glutamicum : a new type of lipidated-modified proteins. Protein mycoloylation is a lipidation pathway exclusively observed in Mycobacteriales, an order...
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Talin and vinculin combine their activities totrigger actin assembly | @scoopit @LeClaincheChri1.
scoop.it
In cells, focal adhesions (FAs) strengthen their connection with the actin cytoskeleton to resist force. By combining biochemistry and cell biology, the authors show that the proteins talin and...
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Cafés de la GS LSH - 22 novembre 2024 avec Denis Faure | @scoopit via @LifeSciencesUPS
scoop.it
Le prochain café se tiendra le vendredi 22 novembre 2024 en visioconférence de 13h30 à 14h avec la participation de Denis Faure (I2BC) qui nous parlera sur « The versatile lifestyle of the plant...
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Conférence : "One Health challenge to control vector borne diseases" - Mercredi 27 novembre 2024 de 9h15 à 12h15 à Henri Moissan | @scoopit via @LifeSciencesUPS
scoop.it
- Are you interested in Parasitology? or - Would you like to discover a field of research at the interface between Biology and Chemistry? or - Would you like to discover new research methods or study...
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RT @VSLioy: Another recently publised article of the @Giglionelab by @meinnel and coll of the #GenomeBiologyI2BC: Peptides fitting the opt….
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RT @VSLioy: By comparing the collection of Next-Generation Sequencing data to the superimposition of several chess games, the team of J. So….
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RT @anne__lopes: very happy to present our latest work on the diversity of RiboSeq signals associated with canonical and noncanonical trans….
genomebiology.biomedcentral.com
Background Pervasive translation is a widespread phenomenon that plays a critical role in the emergence of novel microproteins, but the diversity of translation patterns contributing to their...
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Reference-free exploration of cancer RNA datasets | @scoopit
scoop.it
Bioinformaticians finds new ways to analyze cancer RNA in very large datasets Cancer cells produce an immense diversity of RNA molecules. Using deep sequencing technologies, scientists explore these...
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The next-generation sequencing—chess problem. | @scoopit
scoop.it
By comparing the collection of Next-Generation Sequencing data to the superimposition of several chess games, we demonstrate the limits of current temporal analysis approaches. The development of...
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Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms | @scoopit #GenomeBiologyI2BC.
scoop.it
Peptides fitting the optimal human NMT Gly-myristoylation recognition pattern act as potent inhibitors. Lys-myristoylation-based inhibitors from these peptides were designed. Each series’ inhibitory...
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Introduction to biological crystallography | @scoopit #biology #structuralbiology #crystallography #cristallographie.
scoop.it
Following the French MOOC 'Voyage au cœur du vivant avec des rayons X : la cristallographie', available on FUN-MOOC from 2017 to 2022, and the book in French 'Introduction à la cristallographie...
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RT @AtDeleris: Very proud to share our second pre-print of the year, this time on the positive crosstalk between DNA methylation and Polyco….
biorxiv.org
Transposable elements are primarily silenced by DNA methylation and the associated histone modification H3K9me2 in many multicellular eukaryotes, including plants. However, in the absence of DNA...
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