David Cruz Hernandez 🌵
@d_dcruzh
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University of Oxford
Joined June 2015
@HeadingtonNews wedding ring found last night on Wilberforce street. Would love to reunite it with its owner. Would appreciate the share.
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In @CellStemCell: a tribute to Charles “Chuck” K.F. Chan (1975–2024). Thank you Tom Ambrosi and Mike Longaker for remembering a brilliant and kind scientist and @StanfordMed colleague gone far too soon: https://t.co/7dxzdoqV6B
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#OnThisDay in 1940 “El Maestro” Francisco Toledo was born. Artist, activist, philanthropist and cultural promoter of Zapotec origin, Toledo dedicated his life to preserve Oaxaca's cultural heritage, leaving an immortal humanistic and artistic legacy celebrated worldwide.
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BOOK I—The Beginnings Losing an illusion makes you wiser than finding a truth.—Ludwig Borne
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Left: Two leading labs show, with an impressive set of experiments, that nucleosome positioning patterns drive chromatin compartmentalization in yeast. (Nature Genetics, 2024) Right: A peniless nobody describes the same concept by analyzing public data. (Current Genetics, 2018)
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1/n: There are some academic papers that are so brilliantly and so accessibly written and so universal in scope that they transcend disciplines and stand as timeless testaments to both great thinking and great writing. Here's a short personal selection:
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Come join us! We are recruiting an RA to support our work understanding blood cancer development and testing new therapies. Great opportunity to learn tissue culture, organoids, cancer biology with @AbAttacks and @AdamMead_Oxford. See Job ID: 169105 at https://t.co/Z2NyYjEiul
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High-throughput and scalable single cell proteomics identifies over 5000 proteins per cell https://t.co/ZFfB8Og2Oj
#bioRxiv
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Looking for an interdisciplinary postdoctoral research experience in neurobiology with expanded independence and dedicated funding? Check out Gladstone’s new NOMIS-Gladstone Fellowship Program. Applications due 1/15/24 https://t.co/zimI14Ptzp
gladstone.org
Applications are now open for the NOMIS–Gladstone Fellowship Program at the Gladstone Institute of Neurological Disease (GIND). This interdisciplinary training and research program offers exceptional...
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Delighted to share the detailed STAR Protocol linked to our recently published GTAC method, which aims to uncover how cooperating somatic mutations alter chromatin regulation at single-cell resolution! @asger_jakobsen @angusgroom @FARadtke @pvyas_oxford
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Huge credit to @asger_jakobsen, @SvenTurkalj, the whole lab, the super stimulating collaboration with @stephxie @andygxzeng Muz and John Dick
How do DNMT3A and TET2 mutant clones impact human haematopoiesis? Excited to share our new pre-print where we identify the cell-intrinsic and extrinsic consequences of mutations in humans with clonal haematopoiesis: https://t.co/V3H7q0TRpj @pvyas_oxford @SvenTurkalj @MRC_WIMM
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Can we amplify RNA without reverse transcription to cDNA? Based on the finding that ssRNA template can be directly amplified by T7 in vitro transcription, we invented LAST-seq for RT-free single-cell RNA sequencing, offering a high capture efficiency. https://t.co/d75lui3rLX
link.springer.com
Genome Biology - Existing single-cell RNA sequencing (scRNA-seq) methods rely on reverse transcription (RT) and second-strand synthesis (SSS) to convert single-stranded RNA into double-stranded DNA...
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We have a research assistant position available to work with me and @StoneOliverA. Join us to help set up in vitro models of human lymphatic endothelial cell development! Working in @OxfordDPAG at the @IdrmOxford. Details: https://t.co/gf0TOEx0Kk
@the_Node #devbio #stemcells
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Delighted to see our paper out today at @CellStemCell ! GTAC integrates #singlecell genotyping to chromatin accessibility profiling, linking genetic and epigenetic tumor evolution. Highlights👇 @pvyas_oxford @asger_jakobsen @angusgroom
https://t.co/fyB1WYXPIK
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Want to work in leukaemia research? Have experience in single cell genomics or would like to gain some? Please apply for @NIH funded postdoc position available in our lab @MRC_WIMM @OxPaediatrics @UniofOxford in collab with @AdamMead_Oxford. Details below. https://t.co/ekn0vuuaYP
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Congrats @mileslinde . I’m glad to see this work being published
Many thanks to @RaviMajetiMD for his unwavering support of this project, and the entire @majetilab for being the best home possible for me during my PhD at @stanfordimmuno. A huge thanks to my co-authors @amycfanphd, @ThomasKoehnke, @AaronTrotmanG, @sarahgurev, @kevinanuno,
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@AAlkahwaji I think modern science (at least my field) needs teams. In particular if you want to write ‚big‘ papers..
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We have two positions open in our lab. If you are at #ASH22 and would like to discuss the posts, please reach out- happy to chat!
We have two postdoctoral positions available in our lab, to study #childhoodALL, funded by @NIH and @The_MRC . Join our team in beautiful Oxford @MRC_WIMM @OxPaediatrics @UniofOxford . Link below for more details, and happy to chat! https://t.co/rXwG7o5tNa
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