Joseph Schacherer
@jo_schacherer
Followers
1K
Following
3K
Media
85
Statuses
1K
Research briefings in @Nature about our latest story on large genomic variations on trait diversity!
nature.com
Nature - Structural variants have a disproportionately large effect on traits such as growth and gene expression.
0
2
6
[nature article ]From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes #T2T #genome
https://t.co/W6CTW1tXeE
0
3
3
One of the most exciting projects of my career, years in the making. Using high-throughput precision genome editing, we mapped the fitness effects of thousands of natural variants—challenging the idea that common variants are inconsequential. https://t.co/l7cMJWikk4
biorxiv.org
The nature of standing genetic variation remains a central debate in population genetics, with differing perspectives on whether common variants are almost always neutral as suggested by neutral and...
3
21
62
Nature research paper: From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes https://t.co/6Xgfo6NWse
nature.com
Nature - A newly compiled atlas of species-wide structural variants and gene-based and graph pangenomes derived from highly complete assemblies of genomes from 1,086 natural isolates enable...
1
23
76
From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes. #YeastGenomes #Pangenomes #GeneticVariation #StructuralVariants #LongRead #Sequencing @Nature
https://t.co/uG7Rv2igqg
0
12
29
#Communiqué 🗞️ Pour la première fois, des scientifiques ont cartographié l’ensemble des variants génétiques d’une espèce. Ce premier "atlas" offre une base de travail pour étudier la diversité des traits et l’impact des variants structurels du génome. 👉 https://t.co/M7fpjnnmpC
0
9
17
From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes https://t.co/HM6S9DQQpt 🧬🖥️🧪 https://t.co/Yw1nbqEfLd
0
15
78
✨ Latest exciting story of @haploteam in @Nature. Here, we go beyond SNPs and built a species-wide atlas of genetic variants in yeast. With >1,000 near T2T genomes, we show how SVs shape the phenotypic landscape. @InstUnivFr @ERC_Research @CNRSbiologie
https://t.co/RE7ec6K6Ru
nature.com
Nature - A newly compiled atlas of species-wide structural variants and gene-based and graph pangenomes derived from highly complete assemblies of genomes from 1,086 natural isolates enable...
0
11
20
The #Yeast26 website is live—start planning your conference attendance now! 🧬 Browse abstract submission topics, key dates, speaker & venue info, details on travel funding, & more: https://t.co/UfHtgZfBev Bookmark the page to stay updated as new information becomes available!
1
1
4
Looking for science and fun by the ocean next June?🧬🌊 Join at the GSA Yeast 2026 meeting in beautiful Asilomar, Pacific Grove, CA! 📅 Save the date: June 14–18, 2026 ➡️
genetics-gsa.org
Visit our website to learn more.
0
2
2
We have a new paper out in Molecular Ecology, led by @DevinBendixsen ! Reproductive isolation due to divergent ecological selection is accompanied by vast genomic instability in experimentally evolved yeast populations https://t.co/ig1xUm8Qit
1
11
18
We are excited to share that our paper (D. Lindenhofer et al.) on SDR-seq, a combined single-cell DNA-RNA sequencing method, has been published in @naturemethods! 🎉 Watch co-author Julia Bauman’s video on how SDR-seq links coding & non-coding variants to gene expression.
What good is a science communication channel if you don't get to talk about your own papers on it occasionally, right?😊 We developed a method to simultaneously sequence single-cell DNA and RNA targets, enabling association of genomic variants (including non-coding!) with gene
4
12
59
Thrilled to share our latest work focusing on graph-based pangenome analysis highlighting structural and functional consequences of allopolyploidization https://t.co/t8HinyTSXJ
biorxiv.org
The emergence of graph pangenomes has significantly advanced the study of structural variants (SVs) across diverse species. However, the impact of complex polyploidization events, particularly...
0
1
6
Happy to share with everyone our latest review published in @AnnualReviews Here we focus in Non-Saccharomyes yeasts, latest achievements, and future work on them https://t.co/DlcoDALtlw written by @pablovilla81, @JenniferMolinet @stephaniebraun @ibiochile + me 👏👏👏
annualreviews.org
Most of our current knowledge about yeast is based on the workhorse Saccharomyces cerevisiae. However, can this yeast represent the vast array of natural yeast life-forms? This review discusses...
1
10
32
📢 Nominate your colleagues for a special lecture to be presented at the Yeast Genetics Meeting, June 13-17, 2026! It will take you 5 minutes and no need to be GSA member! https://t.co/Nsb88lD2jq
0
3
2
📢 Nominate your colleagues for a special lecture to be presented at the Yeast Genetics Meeting, June 13-17, 2026! It will take you 5 minutes and no need to be GSA member! https://t.co/Nsb88lD2jq
0
3
2
Why are antiungals often ineffective? We mined current clinical guidelines, and found that many drugs that are administered to patients with high risk of fungal infections, interfere with antifungals.
microbiologyresearch.org
0
6
11
The Yeast2025 meeting in Paris is over, and was so much fun. It was exciting to see a room full of yeast biologists, with more than 500 people. It was also great to be part of the dream team of organizers, led by Gilles Fischer!
1
1
17