A new review paper from our lab courtesy of @JazzSynBio is published in @TrendsinBiotech - In this review, we look at the many opportunities for synthetic biology to be used in the research and applications of Holobionts.

“Valuing BioRender at $900 million” ??!??

Silicon Valley Thinker: Look at those academics bragging about getting a grant instead of discovering science, their incentive system is all broken. I am very smart Next tweet: I’m pleased to announce my startup has had a large fundraising round, that’s how you know we’re real!

The import of biological research material is a silent barrier to biotechnology in the Global South https://t.co/87wG1nZFg8

There's a recent blog from @OpenAI where they used GPT-5 to optimize a common biology experiment, called Gibson Assembly. I've seen criticisms online from people who say things like, "Who cares? A human totally could have done that" or whatever. And that's true. But I still think

A scalable architecture for tuning multistate differentiation ratios in synthetic microbial consortia https://t.co/pjT2L9bzDz #biorxiv_synbio

And another exciting preprint. This time in Engineered Living Materials. It’s a busy week on biorxiv

A long standing goal in synthetic biology is ‘PURE makes PURE’ - effectively the start of self-replicating biology in a tube from just adding biochemicals and DNA instructions. This looks like a promising breakthrough from the Maerkl lab. 👀

Unusually broad-spectrum small-molecule sensing using a single protein scaffold "the ligand-binding pocket of plant hormone receptor PYR1 is malleable, allowing it to be engineered to respond to structurally unrelated ligands such as TNT, PFAS" https://t.co/drKLZQi64P

So you think your mammalian plasmids have nothing to fear from cloning and propagation in E.coli?Quantitative profiling of millions of nucleotides by @tom_copeman will prove you wrong! Supervised with the amazing @ProfTomEllis and AZ, now on BioRxiv: https://t.co/YLr63iOgzh

New work from Francesca Ceroni's mammalian #synbio group - really cool study by Tom Copeman with input from AstraZeneca. I've been lucky to be part of this one. @ceronifranci

We have an opening to work in collaboration with Rodrigo Ledesma Amaro and colleagues at Bayer on filamentous fungi engineering! Check this out:

Same season, same situation but a different intention. Why? #NUFC

Excited to release the fully open-source code for gRNAde - our wet-lab validated, generative AI framework for 3D RNA inverse design 🚀⭐️ I pride myself on open-science & this is probably the most intense release I've done!

AI-designed proteins that survive 150 °C and nanonewton forces Proteins are usually fragile machines. Heat them, pull on them, or send them through a high-temperature sterilization step (like those used in hospitals), and most will unfold and aggregate, losing their function.

Today, we're launching our first round of Edison Grants. These fast grants will provide 20,000 credits (100 Kosmos runs) and significant engineering support to researchers looking to use Kosmos and our other agents in their research. Key details: -PIs, staff scientists,

⏳ One week left! Early bird registration for #Pichia2026 closes soon – don’t miss discounted rates! 📢 Abstract submissions close 19 Dec. Join us for an inspiring conference! 👉 https://t.co/083R6pHdyv

How to build a genome: Scientists release troubleshooting manual for synthetic life

Intrinsically disordered regions facilitate target search to drive promoter selectivity by a yeast transcription factor:

🚨 Last call for the 'AI, Engineering Biology and Beyond' conference taking place in Bristol on the 15-16 January 2026. There is a limited capacity and some places are still left, but worth signing up soon before the 19th December deadline! Register at: https://t.co/HXdAJr78OV

New work describes our efforts to achieve CRISPR editing of the mitochondrial genome. https://t.co/L98rtFj5Yq The CRISPR toolbox has revolutionized the study of nuclear DNA, but the mitochondrial genome (mtDNA) has remained out of reach, mainly because there are no known ways