Gavyn Bee
@cwb315
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Helen Hay Whitney Fellow @CadwellLab @PennMedicine studying immune development previously @WeiserLabNYU @nyulangone
Joined February 2019
Feels surreal but here it goes! Elated to share that my primary research from @WeiserLabNYU @nyugrossman @nyulangone is now out at @ImmunityCP! Tweetorial ahead! 1/n 🧵 https://t.co/Bg6SosK5iN
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New research out in @NatureMicrobiol finds that environmental stress drives clearance of a persistent enteric virus in mice ft. Christin Herrmann, Abigail Lustig, @cwb315, @CadwellLab (@PennGIHep) & Eva Agostino (@CAMBUpenn) https://t.co/VBerOMVv5u
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Congratulations @YingHanChen7121 and Kim Zaldana for showing how B cells are altered when lab mice are released outdoors! https://t.co/yrts4bOXlm 1/n
science.org
Releasing laboratory mice into the natural environment enhanced maturation and activation of the humoral immune system.
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THRILLED to share our recent work on dietary zinc deficiency worsening Acinetobacter baumannii pneumonia, out today @SpringNature in @NatureMicrobiol with @EricSkaar Lab. SharedIt link: https://t.co/D76AmI9U7n Eat your zinc rich foods! 🦪🫘🧀🥩🥜
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Check out this beautiful story led by @ChristinViral @CadwellLab! A virus that persistently infects the gut can be cleared in an unexpected manner: by the body's response to a change in your immediate surroundings
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Early-life sugar restriction—beginning in utero—can protect against diabetes and hypertension later in life, according to a new study leveraging data from post-World War II sugar rationing in the U.K. The findings highlight critical long-term health benefits from reduced sugar
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New paper out @Nature - why are males more vulnerable to severe infections (ex acute #COVID), while females suffer more from autoimmunity (SLE, MS etc and also #LongCovid)? sex chromosomes or hormones? Here we studied adaptation of human immune systems to gender-affirming
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Short-lived Ly6G+ #macrophages help repair lung damage after #flu infections in mice. Learn more in Science #Immunology: https://t.co/MQXtVUGcW1
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‼️I think it is time to make this post!! I am thrilled to announce that the Noval Lab has opened its doors at the Department of Microbiology at @IcahnMountSinai and it is also an associate member of the @SinaiHeartBlood!
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Check out the latest from our group aimed at understand how immune cells adapt coordinate metabolism with epithelia to survive in harsh inflammatory environments.@ipsitassubudhi @KoniecznPiotr @ImmunityCP
cell.com
How immune and epithelial cells simultaneously fuel their dysfunction in chronic skin diseases is unclear. Subudhi and Konieczny et al. find that IL-17-induced epithelial HIF1α activates glycolysis,...
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Why are infants susceptible to invasive pneumococcal diseases? Excited to share our latest work led by @LokkenToyli which explores this question and elucidates the age-dependent mechanisms that drive pneumococcal spread from the mucosa. @PLOSPathogens
https://t.co/98o6PyLWsf
journals.plos.org
Author summary In children, bacterial respiratory and gastrointestinal pathogens remain major contributors to childhood mortality worldwide. Yet, the immune deficiencies intrinsic to early age that...
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Paternal microbiome perturbations impact offspring fitness @Nature
https://t.co/dwQHbNkRxa
nature.com
Nature - Disturbances in the gut microbiota of male mice manifest as fitness defects in their offspring by affecting plancenta function, revealing a paternal gut–germline axis.
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Really elegant delineation of how circadian rhythms during pregnancy impacts offspring innate immune function https://t.co/0do7hphK1W
nature.com
Nature Metabolism - In mice, disruption of circadian rhythms during pregnancy aggravates neonatal inflammation via metabolic reprograming of myeloid cells in the offspring.
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Congrats to @LokkenToyli and team on identifying how Vitamin A deficiency hampers neutrophil development, and the unexpected role of a protein transporter typically associated with macrophage fxn as a critical compromised effector!
🚨 It's finally here! 🚨 A true labor of love! A part of my PhD thesis is out now @NatureMicrobiol
https://t.co/4FsCECFgf1
@vdiazochoa @TsolisRenee Our study unveils a novel insight into the role of vitamin A in immune function, particularly in neutrophil development. (1/2)
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it's not just maternal Abs that help shape infant flora, complement in milk does it too 🤯
Complement components in breast milk shape the offspring’s evolving gut commensal microbiota, conferring protection against enteric infection @CellCellPress
https://t.co/gbMhsr70hS
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Thrilled to share our latest paper on commensal colonization during early life! This study explores how human milk oligosaccharides trigger the colonization program in Bacteroides fragilis. 🍼👶🦠 https://t.co/AlG7jDS3qp
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A huge shout out @kimaimytran and the entire team and collaborators Happy to share our study @NatImmunol showing how BCG generated effector memory T cells provide cross-protection against influenza virus via lung trained immunity https://t.co/d5M5kK7J1b
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Over the moon to have my manuscript up on bioRxiv 🤩
GM-CSF-mediated epithelial-immune cell crosstalk orchestrates pulmonary immunity to Aspergillus fumigatus https://t.co/LCbMsMzRkq
#biorxiv_immuno
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🚀 Now launching our Top Posts of the year! This @ImmunityCP study investigated age-dependent differences in susceptibility to certain infections. Great work by Gavyn Chern Wei Bee (@cwb315) from @WeiserLabNYU & collaborators! ❇️ https://t.co/DWeui5u54k
Here's a good read! 📚 Research led by Gavyn Chern Wei Bee (@cwb315) from @WeiserLabNYU reveals how age-dependent differences in #efferocytosis determine infection outcome. @nyugrossman @nyulangone Learn more at @ImmunityCP: 📑 https://t.co/ahhQG0oFC0
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Congrats @Liwen_Deng811 @IsaacChiuLab! Such an elegant and detailed delineation of a specific microbial factor that can trigger itch behavior during infection.
Excited to share our story about S. aureus and itch! https://t.co/2fc2v3bvD8
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