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Official twitter account of the Cell & Molecular Biology (CAMB) Graduate Group 🧪🔬 @pennbgs @Penn Also on Blue Sky username=cambupenn
University of Pennsylvania
Joined June 2015
RT @hellolabjilly: Haven't posted on here in a long time, but I'm happy to announce the publication of my paper in Frontiers in Immunology,….
frontiersin.org
Pseudomonas aeruginosa is a high priority multi-drug-resistant (MDR) bacterial pathogen with increasing resistance against broad-spectrum antibiotics. Multip...
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Alum Daniel Morris (@the_djmorris) from the Shaw lab has a new first-author publication on: Transient glycan shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques
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Yohaniz Ortega-Burgos (@YohanizOrtega) in the Oliver and @FChrisBennett labs defends her thesis tomorrow!
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Dr. Randi Isenhart (@isenhartrandi) has a new 1st author publication for her work in the @ericjoycelab on: The length and strength of compartmental interactions are modulated by condensin II activity:
journals.plos.org
Author summary The three-dimensional organization of the genome plays a critical role in regulating cellular function, yet the mechanisms that govern large-scale chromatin architecture during...
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Alum Siera Tomishima (@SieraTomishima) from the @OliverLab1 has a new paper out on: The E3 ubiquitin ligase Cul5 regulates hematopoietic stem cell function for steady-state hematopoiesis in mice
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Kimberly Apodaca in the Linette lab defends her thesis tomorrow!
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Aishwarya Pawar in the Paralkar lab defends her thesis tomorrow!
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RT @PennMedCSO: Improving T-cell responses to vaccines ft. @emilyaunins (@CAMBUPenn), @KingOfPathogens, Anthony Phan (@PennVet), Susan Domc….
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CAMB alum Dr. Haig Aghajanian (@Haig_Ag) of Capstan Therapeutics and UPenn's Perelman School of Medicine in the corresponding author role with @CarlHJune: In vivo CAR T cell generation to treat cancer and autoimmune disease | Science
science.org
Chimeric antigen receptor (CAR) T cell therapies have transformed treatment of B cell malignancies. However, their broader application is limited by complex manufacturing processes and the necessity...
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New first author paper (Editor's pick!) out for Priyanka Chatterjee in the Pohlschroder lab (@pohlschr) on: Quorum sensing mediates morphology and motility transitions in the model archaeon Haloferax volcanii | mBio
journals.asm.org
Understanding the complex signaling networks in microbial communities has led to many invaluable applications in medicine and industry. Yet, while archaea are ubiquitous and play key roles in...
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First author for alum Dr. Daniel Morris (@the_djmorris) from his thesis work in the Shaw lab on: Transient glycan shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques: @CellReports
cell.com
Broadly neutralizing antibodies (bNAbs) targeting the CD4-binding site (CD4bs) are rarely elicited in HIV-1 infection. Transient deletion of glycans surrounding the CD4bs in simian-human immunodefi...
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New preprint for Amy Gladstein (@amygladstein) in the @Feldserlab on: The H3 K36M oncohistone inhibits NSD2 to activate a SETD2-dependent antiviral-like immune response in KRAS-driven lung cancer
pubmed.ncbi.nlm.nih.gov
Mutations in histone 3 at or near lysine 36 (H3K36) have dominantly acting oncogenic effects in multiple tumor types by limiting H3K36-directed methyltransferases. Paradoxically, we find that...
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New preprint for Rumi Habib (@rumihabib) alum of the Shaw lab on: Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development
pubmed.ncbi.nlm.nih.gov
Broadly neutralizing antibodies (bNAbs) are rarely elicited during HIV-1 infection. To identify obstacles to bNAb development, we longitudinally studied 122 rhesus macaques infected by one of 16...
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New review article published by Maya Hale (@MayaAHale) in the @BashawLab on: Emerging roles for E3 ubiquitin ligases in neural development and disease
frontiersin.org
Neurodevelopment is an intricate process with highly regulated, overlapping stages including neuronal differentiation and axon guidance. Aberrations during t...
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Jesse Pace in the Kahn lab defends his thesis tomorrow!
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