Jason.cosgrove47 Profile
Jason.cosgrove47

@cosgrove47

Followers
344
Following
3K
Media
29
Statuses
776

Principal Scientist in Computational Medicine | Immuno Oncology and Hematology | Single Cell | Omics | Systems Biology | Drug Discovery

Paris, France
Joined March 2020
Don't wanna be here? Send us removal request.
@cosgrove47
Jason.cosgrove47
1 year
Proud to announce that I received ERC Stg & wellcome trust awards to start my group. I have however declined both in favour of a position in the private sector where I am able to do innovative & impactful science in a way that best fits my personal circumstances & ambitions.
@ERC_Research
European Research Council (ERC)
1 year
📣 The latest ERC Starting Grant competition results are out! 📣 494 bright minds awarded €780 million to fund research ideas at the frontiers of science. Find out who, where & why 👉 https://t.co/L6PimhW50v 🇪🇺 #EUfunded #FrontierResearch #ERCStG @HorizonEU @EUScienceInnov
8
3
45
@cosgrove47
Jason.cosgrove47
2 months
0
0
0
@cosgrove47
Jason.cosgrove47
2 months
Glad to see concrete steps being taken to fix publishing issues. One reason I enjoy my current role in industry: I still get to publish with great academic teams, but my career doesn’t depend entirely on it—and neither does the development of young researchers in my team.
@OdedRechavi
Oded Rechavi
2 months
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has
1
2
13
@MilsomMick
Mick Milsom
2 months
Surprising finding that standard chemo treatment induces resistance to menin inhibitors in AML. Published in @ISEHSociety journal Exp. Hem:
Tweet card summary image
exphem.org
Inhibitors of the menin-KMT2A interaction are promising agents for the treatment of KMT2A-rearranged leukemias. We evaluated menin inhibition in patient-derived xenografts of KMT2A-rearranged...
0
15
49
@andygxzeng
Andy Zeng
7 months
Excited to see BoneMarrowMap out in press! Please check out the R package (now capable of classifying 100,000 hematopoietic cells in 10 minutes) and consider giving the paper a read for some insights into how differentiation goes wrong in AML!
@BCD_AACR
Blood Cancer Discovery
7 months
Online now concurrent with #AACR25 #hematooncology Minisymposium talk by @andygxzeng and Dr. John Dick team @PMResearch_UHN: Single-cell transcriptional mapping reveals genetic and hierarchy-based determinants of aberrant differentiation in AML. https://t.co/gKNyA5rQpK
6
18
73
@cosgrove47
Jason.cosgrove47
7 months
Thanks for flagging @Adrien_Jolly_ . Quantification of cell cycling is definitely not trivial - when we looked at the cycling numbers in HSPCs in the literature they were all over the place.
@Adrien_Jolly_
Adrien Jolly
7 months
This is super frustrating to see this out in Nature because people will reuse their approach. Their way to determine total cell cycle duration (Tc) makes no sense (see thread).
0
0
2
@cosgrove47
Jason.cosgrove47
9 months
I no longer recommend academic careers for people from working class backgrounds. Hard to get to a financially stable position when you dont have additional means to make up for such low salaries. Academic science can be fun, but lets drop the pretence that it's inclusive.
@Nature
nature
9 months
The importance of diversity in science is an unshakeable reality that the scientific community must stand by, says Arthur Caplan https://t.co/1c8DZCkN2F
1
0
8
@JCupovic
Jovana Cupovic
11 months
Alert Stromal Cell Marvels, my newly established group at Uniklinik Freiburg, is seeking a student for a Master/PhD project. If you are interested in stromal cell-immune cell interaction at the borders of the CNS and beyond – drop me a message.
5
6
15
@tangming2005
Ming "Tommy" Tang
11 months
tidyplots is an R package to generate publication-ready plots for scientific papers https://t.co/NUMfIyJ7Wi #rstats
3
228
1K
@dalessandrolab
Angelo D'Alessandro
1 year
Blood is a window on systems health. Great work from Higgins and colleagues @Nature shows that stability or setpoints in complete blood count parameters in 10s of thousands of patients over 20 years is associated with clinical risk and all cause mortality https://t.co/XZeO71ykIK
0
4
14
@DanPollyea
Daniel Pollyea
1 year
Thanks for highlighting this really important effort to develop new prognostic criteria for new therapies. Have to do this for all new therapies, can’t assume that risk stratification systems developed for other therapies are relevant. More input and refinement to this is needed!
@BloodPortfolio
Blood Journals Portfolio
1 year
ELN 2017 and 2022 prognostic classifiers did not adequately stratify OS outcomes for patients with AML treated with venetoclax-azacitidine. https://t.co/ADbOo9RSbH #clinicaltrialsandobservations #myeloidneoplasia
1
6
36
@AlejoFraticelli
Alejo Rodriguez-Fraticelli, PhD
1 year
Unbound by formats or JIF - eLife is now completely upsetting the way science results are shared through short reports. No more story-crafting, no more eternal revisions. PhDs may actually start graduating with a published paper. Get ready to get scooped by reports on eLife.
@eLife
eLife - the journal
1 year
High impact, small size. We welcome papers that address findings from a single set of experiments, or that are substantial enough to stand alone in 1,500 words or fewer. Find out more: https://t.co/FklHAprPC8
6
12
96
@cosgrove47
Jason.cosgrove47
1 year
A great opportunity available at Servier for anyone interested in applying AI approaches to disease modelling https://t.co/vZm8TSf8Dc
Tweet card summary image
nature.com
AI/ML Postdoc position. Applicants are welcome to submit their research proposal in Gliomas disease progression or in silico formulation prediction.
0
1
2
@andygxzeng
Andy Zeng
1 year
I’m excited to share an R package that we’ve created for mapping scRNA-seq data across normal and malignant hematopoiesis! We've used this to identify hematopoietic stem cells from healthy tissues and map leukemia cells from hundreds of patients. 1/6 https://t.co/NW4aMMFUsx
Tweet card summary image
github.com
A single cell RNA-seq reference map of human hematopoietic development in the bone marrow, with balanced representation of hematopoietic stem and progenitor cells and differentiated populations - a...
3
41
180
@tangming2005
Ming "Tommy" Tang
1 year
scplotter provides a set of functions to visualize single-cell sequencing data in an easy and efficient way. https://t.co/zq0laaHcRQ
4
76
333
@ruairirobertson
Ruairi Robertson
1 year
A new bank of >2000 scientific/medical images and icons for free use in figures and presentations just released by @NIAIDNews @NIH. Very useful for early career researchers who can’t afford @BioRender https://t.co/rfcWhJLnL6
5
53
187
@fabiohecht
Fabio Hecht
1 year
🚨 Preprint alert! Our new work uncovering that glutathione (GSH) boosts tumor growth by supplying amino acids is now available at @bioRxiv! Check it out 👇🏼and follow along for the #tweetorial (1/10) https://t.co/RpyACVbufW
Tweet card summary image
biorxiv.org
Restricting amino acids from tumors is an emerging therapeutic strategy with significant promise. While typically considered an intracellular antioxidant with tumor-promoting capabilities, glutathi...
8
16
85
@cosgrove47
Jason.cosgrove47
1 year
Really good training block with 165kg squat, 100kg bench and 210kg (soft lockout) deadlift. Onwards and upwards @ScientistsLift #scientistswholift
0
1
6
@cosgrove47
Jason.cosgrove47
1 year
Very frustrating to hear that all these fantastic new medicines exist but patients aren't getting access to them.
@FundImmuno
Fund Immunotherapy Ireland
1 year
My name is Bernard, living in Ireland. I have stage 4 stomach cancer. My medical consultants recommend Immunotherapy and chemotherapy. Despite best scientific and clinical evidence, my Irish healthcare insurer won't fund this. Am I alone?
0
0
2
@cosgrove47
Jason.cosgrove47
1 year
Plenty of fun ways to do science - academia isn't the only show in town
@dr_alphalyrae
Vega Shah
1 year
we’re not quitting science, we’re quitting academia. I am still very much in science and will remain here forever
0
0
2