Princess Margaret Cancer Centre Research
@PMResearch_UHN
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Research arm of @pmcancercentre—the largest integrated #cancer research, teaching and treatment centre in Canada. @UHN
Toronto, Ontario
Joined April 2019
🌟“Surprise is always the strongest signal that you found something new.”. Research from @GairdnerAwards awardee @decarvalho_lab is unlocking powerful new tools impacting cancer clinical care, from interception, detection to therapy design and monitoring.
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Congratulations to all those honored at the 14th Annual PM Research Retreat! The theme for 2025 was "It takes two to think", aiming to build collaborations among scientists and clinicians. Check out our 2025 research awardees and Papers of the Year here:
Congratulations to UHN's June Honour Roll!. 🏅 Hugh Amiel, @cppcccmp Passion for Procurement recipient.🏅 @pmcancercentre 14th annual Research Retreat awardees.🏅 Data & Analytics team at @TheDataIQ Awards.🏅 @UHN_Surgery Recognition Awards. Read more:
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A switch between blood cancers🩸. Study found “multipotent” cancer cells can switch cell lineages, leading to a higher risk of drug resistance and worse outcomes. A discovery led by Dr. John Dick @UHN @pmcancercentre & Dr. Charles Mullighan @StJudeResearch.
A study published today in @NatureCancer from @PMResearch_UHN and @StJudeResearch has mapped how human blood #StemCells create the blood lineage and uncovered why blood #cancer lineages can sometimes switch following #chemotherapy. 🔗Read more:
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🧬 The team also found that PRMT inhibitor could improve SCLC treatment outcomes from an epigenetic point of view: A PRMT inhibitor (MS023) disrupts splicing, increases DNA damage & shows strong synergy with chemo & radiation. Published in Neoplasia:
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🔬 New strategy to boost immunotherapy for small cell lung cancer (SCLC): Combining PARP inhibitors + radiotherapy activates immune pathways & boosts T cell-attracting chemokines, discovered by @BenLok’s team at @UHN @pmcancercentre. Read in @NatureComms:
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Congratulations to our scientist Dr. Bowen Li on receiving an Early Career Researcher Jump Start Award to support his project entitled: “Nonviral delivery of prime editors for gene therapy of cystic fibrosis”🎉.
🚨 Big news in #StemCell and #RegenerativeMedicine! . @UHN researchers receive $3.1M from the @StemCellNetwork to support innovative research, including three-UHN led projects. Congratulations to all the teams! . 🔗 Read more:
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🧬Also check out his latest review: Advances in lung cancer basic and translational research in 2025 – Overview and perspectives focusing on non-small cell lung cancer. A deep dive into where the science is headed.
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📊A study led by our Senior Scientist Dr. Ming Sound Tsao confirms the 9th edition TNM staging system is valid for high-grade pulmonary neuroendocrine carcinomas, including new N2 & M1c subcategories. A step forward in accurate prognosis & care.
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At @PMResearch_UHN, we work seamlessly to deliver world-class health care, conduct groundbreaking research, and educate tomorrow’s health leaders. We’re excited to continue our work, united under a bold, new brand. We’re a proud part of UHN – Canada's Hospital 🇨🇦.
Today, we are thrilled to reveal our refreshed brand, a bold and modern reflection of the full scope of who we are and what we do. We are UHN – Canada's Hospital 🍁 . Learn more at:
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Cancer Cells Relay Messages to Coordinate the Spread. CellNEST, an AI tool developed by Dr. @Schwartastic's team, found that the tumour microenvironment may relay messages in a "two-hop" fashion, fuelling the spread of #PancreaticCancer. @naturemethods:.
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RT @uhntrainees: Congrats to Dr. Mark Gower on receiving the ALSF Young Investigator Grant! 🧬🎉 A postdoc in Dr. Tikhonova’s lab at @PMResea….
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RT @pmcancercentre: Thank you to everyone who joined us for Journey to Conquer Cancer this weekend in support of life-saving cancer researc….
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A new tool, moPepGen, developed by @uhn @pmcancercentre & @UCLAHealth, can predict & detect unusual proteins involved in cancer and beyond, deducing what cellular processes might have gone wrong to give rise to these mutant peptides. @NatureBiotech:.
checkout our latest paper in @NatureBiotech. We developed a graph-based algorithm that comprehensively generates non-canonical peptides in linear time.
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RT @UHN_Research: How do some cancers shift to become more deadly?. Researchers at @PMResearch_UHN have identified an RNA molecule that hel….
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RT @uhntrainees: 🌟 Meet Elyse Digby! 🌟.PhD in Organic/Bio Chem (U of T), postdoc at @PMResearch_UHN, now an MSL at Novartis! Hear her journ….
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An exciting day to explore immune therapy beyond cancer!.
🚀 Kicking off the inaugural Ci2i Launch Symposium at the iconic @MaRSDD!. Today, we unite clinicians & researchers across @UHN & @UofT to accelerate innovation in #immunotherapy, from #cancer to #RegenerativeMedicine. 🔗#Ci2iLaunch
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RT @UHN_Research: 🚀 Kicking off the inaugural Ci2i Launch Symposium at the iconic @MaRSDD!. Today, we unite clinicians & researchers across….
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