Fangyuan (Chelsea) Chen, MD
@chelseachenmd
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Postdoctoral Research Fellow @DanaFarber, #Bioinformatics #PrecisionMed #Oncology
Boston, MA
Joined September 2018
RT @YanHu41082612: Super excited to share our new study from the @JD_Buenrostro Lab in @Nature! We developed a computational method for tra….
nature.com
Nature - We developed PRINT, a computational method that identifies footprints of DNA–protein interactions from bulk and single-cell chromatin accessibility data across multiple scales of...
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Honored to contribute alongside such an inspiring team @ZheqiL LiChen JiebinLiu (and others). Grateful to our wonderful mentors @Adrianvlee @oesterreichs for the their guidance, and collaborators @GertzLab @mjsikora @JCarrollLab @LabPolyak (and many) for their suggestions and.
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Besides visualization of original datasets, the browser ( also enables cross-dataset signature score calculation of user-defined gene sets ( Analysis -> Mode 2), (co)expression pattern visualization of user-selected single genes.
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The current upgrade of EstroGene2.0 ( curated and analyzed breast cancer cell line data under endocrine therapy, and the endocrine resistance models, including transcriptomics, ChIP-seq, and ER RIME datasets from 361 experiments in 212 studies across 28.
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In EstroGene1.0 (, we focused on E2-triggered ER activation in breast cancer cell lines from 246 experiments including 136 transcriptomic, cistromic, and epigenetic datasets. Learn more
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Glad to share our latest work on The EstroGene2.0 database for endocrine therapy response and resistance in breast cancer models, now published in @Nature_NPJ #npjBCancer, with the super-multifunctional browser
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Thrilled to see Dr. Mittendorf @EMittendorfMD officially announced as the 2026-2027 @ASCO President! Honored to be part of the T-hub team and much inspired by her leadership #ASCO #Oncology #Leadership.
Congratulations to Dr. Elizabeth A. Mittendorf on being elected to serve as ASCO President for the 2026-2027 term! Six additional members were elected to positions on the ASCO Board of Directors & Nominating Committee. Read more >
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RT @stolaney1: What an amazing breast oncology group! I feel very lucky to be surrounded by such incredible colleagues @DFCI_BreastOnc ! h….
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RT @NatureRevGenet: The lives of cells, recorded #Perspective by @AskaryLab, Wei Chen, @_Choi_Junhong, Lucia Y. Du,….
nature.com
Nature Reviews Genetics - Recent advances in genome engineering are enabling the recording of cellular histories into genomes, with single-cell and spatial omics technologies enabling their...
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RT @CellRepMed: Online now: Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for ea….
cell.com
Campbell et al. utilize multiplex immunofluorescence staining, gene expression profiling, and reverse phase protein arrays to gain insights into the role of the tumor immune microenvironment during...
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RT @EricTopol: The human proteomic revolution proceeds with high-throughput assessment, AI analytics, correlation with health and disease,….
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RT @nicholas_navin: New paper from our group in @Nature by @YiyunLin_YL @junkewang @KaileWang and team reporting the unexpected discovery o….
nature.com
Nature - Using single-cell DNA sequencing we show that most healthy women harbour rare populations of aneuploid epithelial cells with copy number alteration events in their breast tissue that...
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RT @ItaiYanai: Out today in Nature: "The Human Cell Atlas"! In my commentary, I compare the cell atlas to early naturalists exploring South….
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RT @XinHuHEcon: Palliative care is NOT just end-of-life care—it supports patients at any stage and improves QoL. We propose a new value fra….
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RT @RyanNipp: Illuminating the Value of #Palliative Care in #Cancer: A Path to Incentivizing High-Value Cancer Care. .
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RT @JAMA_current: Acupuncture might be an effective treatment for patients with chronic sciatica from a herniated disk. Read JAMA News in….
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Likewise!😊.
Incredibly grateful for the opportunity to attend the 6th Annual Carolyn Kaelin Lecture with Dr. Kelly K. Hunt as our guest speaker. A true pioneer and living legend in breast surgical oncology and collaborative efforts in the field. #bcsm @BrighamWomens @DFCI_BreastOnc
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RT @NatRevDrugDisc: Senescence as a therapeutic target in cancer and age-related diseases This new review evaluate….
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