BuchnerLab
@buchnerlab_tum
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Welcome to the world of protein science! This is the account of the Buchner Lab of Biotechnology @TU_Muenchen -student run account-
Munich
Joined November 2019
We are honored to receive an ERC Synergy Grant for our project CHAPEROME! Together with Judith Frydman (@FrydmanLab) and Marina Rodnina (@mpi_nat), we aim to reveal how chaperone networks regulate translation. Read more: https://t.co/49xnUOqY8A
tum.de
Disease-causing proteins – ERC Synergy Grant for research at TUM on the role of chaperone “helper proteins.”
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How to ensure IgM antibody assembly with the desired stoichiometry? @chiaragiannone3 @buchnerlab_tum Roberto Sitia et al show how J-chain outcompetes the sixth dimeric IgM subunit during pentamer assembly & what prevents secretion of aberrant conformers https://t.co/8tUXs29UO7
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Our❄️December❄️issue is live! Depicted on the cover - how #sHSPs 'catch' non-native proteins to protect the proteome. Read the Review "Catchers of folding gone awry: a tale of small heat shock proteins" from @buchnerlab_tum and colleagues. Find it here: https://t.co/7VXxJao864
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Had the wonderful opportunity to share and discuss our recent findings on CHIP and chaperones in @buchnerlab_tum with none other than David Agard @AgardLab at #Hsp90 conference 2024 at Seeon.
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Thanks @buchnerlab_tum for organizing such an amazing meeting! Sorry for missing it. So many familiar faces @Bio_BRU @lab_colombo C. Prodromou @bourboulialab @HawleLab @TheMarq1 B. Blagg @BiophysK @KravatsLab @AgardLab M. Mayer.
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Authors from @buchnerlab_tum show that the conformational transitions during the Hsp90 ATPase cycle are conserved from yeast to humans. https://t.co/kbhcPjEhai
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We are happy to share our latest publication out in Nature Communications! This paper sheds light on the conformational dynamics of Hsp90! Awesome collaboration with @TheKailaLab and the Don Lamb Lab! https://t.co/c3JdGV22tp
@NatureComms
nature.com
Nature Communications - Hsp90 is a molecular chaperone important for protein homeostasis. Here, the authors show that the conformational transitions during the Hsp90 ATPase cycle are conserved from...
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Excited to share that our new review “Catchers of folding gone awry: a tale of small heat shock proteins” is published! Check it out:
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The BiP binding site server (BiPPred) is online and accessible again! Check it out:
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We are excited and proud to share that Johannes received the prestigious Otto Warburg Medal 2024 in recognition for our pioneering work on protein structure formation and the role of chaperones from the @GBM_eV. Of course we are especially looking forward to the upcoming party!!
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Congrats to Johannes Buchner @buchnerlab_tum, this year´s #OttoWarburgMedal winner, for his fundamental contributions to the structure formation of proteins and the role of #chaperones. #OWM24 #MosbacherKolloquium @ElsevierConnect @BBAjournals Read more: https://t.co/mz6kfUGCtm
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We are happy to share our latest publication on the question of what happens when an organism can no longer respond to cytosolic proteotoxic stress. @MoeMuehlhofer @FebsLetter1889
febs.onlinelibrary.wiley.com
What happens if an organism can no longer react to cytosolic proteotoxic stress? To answer this question, we deleted or depleted the stress-responsive transcription factors Msn2, Msn4 and Hsf1 in...
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📢In recognition of his fundamental contributions to #ProteinStructure formation and the role of #chaperones, Prof. Johannes Buchner @buchnerlab_tum @TU_Muenchen will be awarded the #OttoWarburgMedal 2024 of the GBM and its sponsors @ElsevierConnect and @BBAjournals🏅Congrats🎉
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🏆 Johannes Buchner @buchnerlab_tum honored with an award by the organizers for his outstanding contributions to the field! 🌟 #ScienceAchievement #AwardWinner #ChaperoneCode @ChaperoneCode @Hsp90Machine #CSSI
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🎉 Exciting news! 🔥 Our ChaperoneCode keynote speaker, @buchnerlab_tum, has been officially inducted as a Senior Fellow of CSSI following his phenomenal keynote address! 🌟 #CSSIFellow #KeynoteSpeaker #CSSI
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It was not all about molecular mechanisms in the #FEBS2023 plenary lecture of Maya Schuldiner yesterday, and this strong message got a standing ovation. https://t.co/v20vJT3YFY
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If you want to meet all the leaders in Stress and Chaperone Biology, then this is the one meeting to go this year👇 Keynotes by @buchnerlab_tum and Matthias Mayer. Speakers @MedMol @TrumanLab @GabrielaChiosis @Bio_BRU @GestwickiLab @bourboulialab
Those flash talks for the Chaperone Code & CSSI meeting (Oct 26 -31) are filling up quickly! Plus a great opportunity to meet all leaders of the field in chaperones, stress responses & proteostasis! If you want to give a flash talk register here:
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