ML4H
@broad_ml4h
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Machine Learning for Health (ML4H) is a collaborative team of ML, clinical, and genomic researchers from across the Broad Institute, MGB, Harvard, and MIT
Cambridge, MA
Joined March 2021
Impactful work led by @emilyswlau to develop a high-fidelity EHR cohort of >56K pregnancies, demonstrating the urgency posed by ⬆️ rates of pregnancy-related CV complications. A call to action. @CircAHA @patrick_ellinor @broadinstitute @broad_ml4h
🚨 New in @CircAHA : Maternal CVD and pregnancy-related CV complications are rising sharply over 2 decades across >56K pregnancies across @MassGenBrigham. Pregnancy is a critical window for lifelong heart health! 🔗 https://t.co/H6d6FvwRdr
@MGBResearchNews #CardioObstetrics
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Attending #ESC2025 @escardio ? Be sure to check out the latest work out of @MACE_Lab_AI ! @ShinoKany @JHaimovichMD @Keisuk_Usuda @broadinstitute @broad_ml4h
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NEW from our group @broadinstitute @MGHHeartHealth @patrick_ellinor led by @ShinoKany and @lucidtronix ECG2CAD: An AI model for detection of coronary artery disease using 12-lead ECGs @JACCJournals
https://t.co/wUKbjRxURI
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Is the ECG secretly a sphygmomanometer? We trained a neural net to predict hypertension from ECGs and found it associated with many cardiovascular outcomes.
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I am excited to share our latest study published @JACCJournals Adv. We found that meeting guideline-recommended physical activity (PA) levels—whether as a “weekend warrior” or via regular activity—is linked to lower visceral and pericardial fat. https://t.co/5mpwVrF7Op
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Just how many diseases can you identify with a good old 12-lead #ECG? NEW @npjDigitalMed, co-led w/ @lucidtronix, @RVpacing & @xwang, we use an autoencoder to map ECG to phenome, finding associations btwn ECG & >600 conditions @broadinstitute @broad_ml4h @MGHHeartHealth LINK⬇️
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🚨 New #ESCCardioTalk episode alert! 🚨 This week, Shinwan Kany & @shaan_khurshid explore another piece in the atrial fibrillation puzzle! 🧩💡 From clinical insights to genetic risk and AI-powered ECG analysis, this episode covers it all! Don’t miss out on the latest in heart
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Many congratulations to @patrick_ellinor! Excited for the future of cardiovascular care, research, and innovation under his visionary leadership!
Patrick Ellinor, MD, PhD, has been named the inaugural Executive Director of Mass General Brigham Heart and Vascular. With his leadership, our system aims to advance heart and vascular care, research and education globally. Learn more: https://t.co/H3S1bMXwqv
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Delighted to welcome @WiroNiessen back to Boston and to a seminar hosted by @MahnazMaddah & broad_ml4h team. Looking forward to the collaborative opportunities between @broadinstitute, @MassGenBrigham & @umcg
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Can AI automate HF adjudication in global clinical trials? Our latest #AHA2024 SimPub @CircHF In the DELIVER trial, our AI model for HF hosp was -Accurate -Generated identical treatment estimate for dapa as human CEC -Extracts evidence of HF Paper: https://t.co/cYslPU1fzP
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Does combining clinical, genetic and ECG-based AI risk scores improve AF risk prediction? Check out our commentary on an interesting study by Jabbour et al. where we describe current key concepts and challenges! with @shaan_khurshid & @patrick_ellinor
https://t.co/QWi7y00k8x
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Is registration of medical images helpful for deep learning Biological models? Yes! https://t.co/As3i2spWKM
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Can ECG #AI predict who will develop #afib after stroke (eg, to prioritize for ILR)? Yes! New in @CirculationEP our @broad_ml4h ECG #AI #afib risk model discriminates cardioembolic stroke (>> clinical factors) & stratifies risk of new #afib after stroke: https://t.co/bfIiX9wXC5
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More good news on the weekend warrior benefits (previously viewed as potential harm) https://t.co/yTbMDk11FR
@CircAHA Among ~90,000 @UK_biobank participants assessed for over 760 conditions with extended follow-up: "Associations appear similar whether physical activity follows a
ahajournals.org
BACKGROUND: Achievement of guideline-recommended levels of physical activity (≥150 minutes of moderate-to-vigorous physical activity per week) is associated with lower risk of adverse cardiovascular...
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Exercise is beneficial for health. But many people have to cram their activity into 1-2 days/week. Do they still get the benefit? To find out, we looked at associations of "weekend warrior” (WW) physical activity) and >600 diseases, now @CircAHA ! A 🧵 https://t.co/lUQM0kjPHl
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Great presentation by @ShinoKany on using an AI model to detect CAD from the 12 lead ECG at #ESCCongress
@aklfahed @broad_ml4h @MGHHeartHealth
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Does combining clinical, genetic & ECG-based #AI risk tools to predict incident atrial fibrillation lead to more bang for your buck? Find out in our new preprint where we developed the comprehensive Predict-AF3 model to estimate incident AF risk. A 🧵 https://t.co/2lqIXsldP4
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Happy to share our latest work out now in @NatureMedicine: Led by the incredibly talented @nauffal_victor, @MarcusKlarqvist, our @broad_ml4h team @broadinstitute used T1 images from the @uk_biobank to assess fibrosis in multiple organs. https://t.co/WRETlCS67g
nature.com
Nature Medicine - T1 mapping noninvasively assesses fibrosis in multiple organs and enables risk stratification of mortality and provides insights into shared and organ-specific pathways underlying...
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In our new @JACCJournals #Advances analysis, we found that 20% of primary care patients @MassGenBrigham had a conduction disorder at baseline and another 6% developed a new conduction disorder over 10 years! @MGHHeartHealth #EPeeps #CardioTwitter 📷 Link:
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Does an automated interpretation of “Possible AF” on 1L ECG predict incident AF in patients without a diagnosis of AF in follow up? Our study out in @hrs_journal now! Huge thank you to @patrick_ellinor @shaan_khurshid @alalusim_md @steven_lubitz et al! #VITALAF
Automated interpretations of single-lead electrocardiograms predict incident atrial fibrillation: The VITAL-AF Trial @DpipilasMD, @patrick_ellinor
https://t.co/NziUQ2OmHV
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