Benoit Bruneau
@benoitbruneau
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Cardiovascular disease researcher, developmental biologist, and Oakland resident. Je cherche a comprendre.
San Francisco Bay area
Joined April 2010
“This is a court of law, not a court of morals,” he said” Oh what a terribly missed opportunity here!
Breaking News: An Australian jury found a woman guilty of murdering three people by serving them toxic mushrooms, ending a trial that had captivated the nation.
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How does heart failure rewire gene regulation? 🔍 Excited to share our single-cell, multimodal epigenomic resource on human heart failure🫀: https://t.co/LG7mrr7x7c.
medrxiv.org
Heart failure is a leading cause of morbidity and mortality; yet gene regulatory mechanisms driving cell type-specific pathologic responses remain undefined. Here, we present the cell type-resolved...
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Grateful & humbled to make the 2025 #TIME100HEALTH list with such inspiring global health leaders. This honor reflects my team, who are unrelenting in their efforts to advance new treatments for pancreatic cancer!
TIME's new cover: Meet this year's #TIME100Health, a community of leaders—scientists, doctors, advocates, educators, and policy-makers, among others—who are changing the health of the world. https://t.co/1MpFEK5mKo
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for #heart month, a nice piece on what we at @GladstoneInst are doing to understand heart disease better. Featuring @m_alexanian @TheodorisLab and Katie Pollard. for heart month, a nice little piece on what we do at Gladstone for the heart
gladstone.org
Bruneau, director of the Gladstone Institute of Cardiovascular Disease, shares exciting recent advances in heart research and talks about the impact of predictive AI.
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The latest from @GladstoneInst of Cardiovascular Research and @ucsf: Isha Jain's lab, with an outstanding discovery of a small molecule that mimics hypoxia, to treat neurodegenerative diseases. The amazing Sylar Blume, RA in Isha's lab, is first author!
cell.com
A small molecule that increases oxygen-hemoglobin affinity was shown to prevent and reverse pathology in a mouse model of mitochondrial disease, thereby enabling a practical form of hypoxia therapy.
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reupping this request to support my daughter's fundraising efforts for the @americanheart It's a worthy cause, and she is learning a lot from it. Thank you for considering.
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Hey there! Please consider supporting my daughter Nika as she raises funds for the American Heart Association as a 2025 Teen of Impact nominee. More than ever we need support for cardiovascular research, and this is a noble way to help. Thank you!
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Thank you to the @NIH @4DNucleome for all they have done to support us, inspire us, and to bring us together. We will need each other more than ever in the coming months as we stand for the future of basic science research.
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Ten years. Together we built a warm, tight-knit, international community, shared new computational and experimental technologies around the the world, posted >400 preprints, and catalyzed understanding of the mechanisms and functions of chromatin in development and disease.
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Hey friends. Come over to the blue skies. It’s warm and friendly and we’re all there.
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Check out this wonderful Perspective piece in @ScienceMagazine by Christina Theodoris @UCSF @GladstoneInst:
science.org
A genomic foundation model broadly enables sequence modeling, prediction, and design
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Happy to share our new work describing DESynR genes! The evolution of new human protein-coding genes relies on repurposing protein domains from ancestral genes, rather than de novo sequence creation. New genes evolved from old parts, and while we have methods that enable
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I'm not giving up. Not letting any political agendas interfere with dissemination of life science and medical stuff via this channel and others. The latter includes Substack, Threads, LinkedIn, Bluesky, and Mastodon.
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The 3rd edition of this comprehensive review on the genetics and biology of #PancreaticCancer is now published in @GenesDev
https://t.co/18JKwjzxo1 Updated information with several useful illustrations and citations. Thanks @RonDePinho @HaoqiangY @rkalluriMDPhD Alec Kimmelman,
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MCRI Prof Enzo Porrello talked to @fox5ny about how a new collaboration between MCRI and @GladstoneInst is using human #stemcells, genomics and AI to solve #childhoodheartdisease. @PorrelloER @reNEW_Global 👉 https://t.co/Nd3zeZEsGG
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Apple Watch pulse alerts about to have a historical day
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