🚨 NEW ISSUE ALERT!!! 🚨 New Outlooks, Review and Research Papers online now at Genes & Development. Click on the link for more: ➡️ https://t.co/6XSv7TxiKm

RESEARCH PAPER: ELAV mediates circular RNA biogenesis in neurons By Alfonso-Gonzalez et al. ➡️ https://t.co/uEvdLQYpH5 #circRNA #neuroscience #RNAbindingprotein #Drosophila #embryos #neurons #mRNA #introns #splicing

REVIEW: Timing is everything: transcription bursting in development By Jee Min Kim and Daniel Larson ➡️ https://t.co/ycbO6nEMUk #transcription #molecularbiology #transcriptionbursting #embryonicdevelopment #stemcell #differentiation #mRNA #development #molecularmechanism

📽️ G&D Tapes 📽️ G&D Author, Edel McCrea tells us about their new study in #genesdev reporting a role for tyrosine phosphatase PTNP14 in the sexually dimorphic regulation of Hippo pathway function. @AttardiLaura Learn more here: ➡️ https://t.co/an6GYH2rcW

RESEARCH PAPER: Analysis of knockout mice reveals critical female-specific roles for the Hippo pathway component PTPN14 By McCrea et al. ➡️ https://t.co/an6GYH2rcW #Hippo #Development #SexDifferences #YAPTAZ #signaling #WoundHealing #PTPN14 #CornealDisease #uterus #WomensHealth

🚨 NEW PUBLICATION 🚨"MEF2C controls segment-specific gene regulatory networks that direct heart tube morphogenesis" in @GenesDev https://t.co/BTMeXPSQ47

📽️ G&D Tapes 📽️ G&D Author, Hedda Meijer tells us about their recent study in #genesdev that demonstrates the functional significance of the interaction between NOTCH1/NICD and the F-box protein FBXW7 during somitogenesis. Learn more here: ➡️ https://t.co/f5PFAcVbfy

RESEARCH PAPER: NOTCH1 S2513 is critical for the regulation of NICD levels impacting the segmentation clock in hiPSC-derived PSM cells and somitoids By Meijer et. al ➡️ https://t.co/f5PFAcVbfy #segmentationclock #NOTCH #NICD #somite #somitoid #embryo #patterning

REVIEW: Studying ovarian aging and its health impacts: modern tools and approaches By Bérénice A. Benayoun, Alison Kochersberger, and Jennifer L. Garrison ➡️ https://t.co/dL58N2keir @BBParis1984 @jenngarrison @USCLeonardDavis #reproductiveaging #aging #womenshealth

1/4 🚨 New Outlook in @GenesDev: "Scaling life as an interspecies hallmark of aging" We propose temporal scaling as a new hallmark—linking lifespan diversity to conserved aging mechanisms. 🔗 https://t.co/4Bd4wOAFsi @HebrewU @GeneticsDepart1

Cells can shut down their metabolism to block viruses like West Nile. A new @GenesDev study from @UFScripps reveals how OAS 3 proteins activate RNase L to halt infection and protect cells. This discovery could help shape future antiviral therapies! 🧬 🔗: https://t.co/8erX9a58JT

Scientists have discovered how genetic mutations drive the rare developmental disorder Weaver syndrome. Led by @adrianbracken in collaboration with researchers in @ucddublin, the study provides insights that may lead to improved therapies. 🔗Read more: https://t.co/5HWAWskhHP

SYMPOSIUM OUTLOOK: C. elegans cognitive decline with age: more than just wiggling forward and backward By Coleen T. Murphy ➡️ https://t.co/CZ9iBaxM5u #animalmodels #elegans #behavior #cognition #memory #aging #cognitiveaging

SYMPOSIUM OUTLOOK: The interplay between senescence, inflammation, and the immune system By Jesús Gil ➡️ https://t.co/azkRtZuTmQ #senescence #aging #immune #SASP #nucleicacid #inflammation #therapy #openaccess

SYMPOSIUM OUTLOOK: Beyond the usual suspects: expanding aging research from classic models to really cool critters By Amy Walker ➡️ https://t.co/4AxpBZv2Z9 #animalmodels #aging #longevity #allometry #immune #metabolism #environment #openaccess #lifespan #genomics

SYMPOSIUM OUTLOOK: Scaling life as an interspecies hallmark of aging By Itamar Harel @ItamarHarel ➡️ https://t.co/pIXJV8UJTp @HebrewU @GeneticsDepart1 #aging #evolution #naturalselection #temporalscaling #mortalityrisk #lifespan #reproduction #environment #molecular

@narita_lab

Our latest review is out in the Genes&Dev @GenesDev special issue on Aging and Senescence: The rise of RAS: how gradual oncogene activation shapes the OIS spectrum https://t.co/Ko8EvZI34W https://t.co/DbXdGMlXvl

SYMPOSIUM OUTLOOK: #Telomeres at the nexus of #aging, #tumor suppression, and #inflammation: toward an understanding beyond #senescence By Samuel Bloom & Jan Karlseder ➡️ https://t.co/UIoVJSTxHI #cshlsymp25 #DNAdamage #replicativesenescence #DNAreplication #crisis #cancer

SYMPOSIUM OUTLOOK: Mitochondria dysfunction: cause or consequence of physiologic aging? By G.R. Scott Budinger & Navdeep Chandel ➡️ https://t.co/AXKbg0cQzS #cshlsymp25 #mitochondria #aging #signaling #ATP #organelles #healthspan #metabolism #DNAdamage #oxidativestress