Jenn Cremins
@CreminsLab
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Laboratory for chromatin and spatial neurobiology. Understanding how synapses and the nucleus communicate in the developing and diseased mammalian brain.
Joined November 2016
We are tremendously excited to share a new 5-year project led by Linda Zhou https://t.co/7rtK7S2PUr. By way of the 3D genome and inter-chromosomal interactions we discover short tandem repeat instability and heterochromatin silencing on autosomes in fragile X syndrome. 1/n
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“In college I got to learn with reps. If I went to Tech or Duke, I may have rode the bench as a Freshman. I don’t know that I get as much better” - Steph Curry on the impact of going to Davidson (Via @ComplexSports 🎥)
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Excitatory synapses on parvalbumin expressing interneurons contain similar AMPA but significantly lower NMDA receptor densities in schizophrenia compared with control subjects. Beautiful study: “Seeing” is believing
#JNeurosci: Lorincz et al. provide novel insights into the molecular mechanisms underlying excitatory synaptic dysfunction in schizophrenia. https://t.co/PgcYVi7aEi
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There will never be another Steph Curry. Enjoy him while you can
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You just knew that this kid was going to be something special the second we heard this from him on draft night…
“The long nights… I lived off a generator for 7 years. I didn’t have electricity - I lived off a generator for 7 years. To see what she had to go through just to feed us? Crazy.” VJ Edgecombe is impossible to dislike & will become a fan favorite in Philly very soon…
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Join @WashUGenetics this Thursday Oct. 23 @12pm in Connor Auditorium when Evan Eichler, PhD,@EichlerLab presents “Complete genomes and complex structural variation”, hosted by Tychele Turner, PhD,@tycheleturner
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The Losonczy Lab in the OBI Program for Memory Longevity seeks #postdocs, particularly an in vitro #electrophysiologist to explore the synaptic and dendritic basis of learning using physiological and imaging tools. #optical-imaging #PatchClamp Learn more: https://t.co/GpiylRCUF4
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For days, I have been trying to write a tribute to our kind, brilliant friend, collaborator and physician, Dr. Nolan Williams @NolanRyWilliams. This beautiful tribute from the veterans Nolan helped, in the post below, has finally unlocked my broken heart long enough to try to
It is with profound shock, deep sadness, and heartbreak that VETS mourns the loss of Dr. Nolan Williams, a beloved friend, ally, and pioneer whose vision transformed the landscape of care for our nation’s veterans. Nolan was not only a brilliant clinician and relentless
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We will carry this challenge for you, Nolan. Be at peace.
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This guys a PRO and I’m pulling for him hard the rest of his career 🫡
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Congratulations to Michael Meers, PhD, on receiving the NIH Director’s New Innovator Award in support of his research developing new tools to guide stem cell differentiation. A well-deserved recognition of his innovative work. https://t.co/Y6k9cEtGpQ
medicine.washu.edu
Three investigators have been recognized with grants from the agency’s High-Risk, High-Reward Research program.
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A Nobel-winning scientist of great modesty and humour, John Gurdon died on 7 October. Not only did he make a discovery that laid the foundations for the field of stem cell research, he also created one of the best environments for research at the Wellcome / CRUK Gurdon Institute.
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Plenty of amyloid, very little tau Low inflammatory response front page @nytimes, by @PamBelluck
https://t.co/DUtJ3EdKHu
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In the latest issue! A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons
cell.com
Neuronal activity triggers PGC-1α-mediated transcriptional programs that drive the late maturation of PV+ interneurons, essential for cortical circuit function. PGC-1α partners with ERRγ and Mef2c to...
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It's clear that a strong sense of purpose in life is neuroprotective--even accounting for age, sex, education, ethnicity, and even APOe status. At the same time, sense of meaning and purpose continue to decline. Something's gotta change
Purpose = brain health A strong sense of purpose in life was linked to a 28% lower risk of cognitive impairment in a 15-year study The protective effect held even after accounting for depression, education, and APOE E4 (genetic Alzheimer's risk)
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Purpose = brain health A strong sense of purpose in life was linked to a 28% lower risk of cognitive impairment in a 15-year study The protective effect held even after accounting for depression, education, and APOE E4 (genetic Alzheimer's risk)
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Nothing but love and respect from the Cremins family for Fran Dunphy. Incredible life, Incredible legacy in dedication and faithfulness to Big Five basketball in Philadelphia
A standing O for Fran Dunphy at this morning’s annual Coaches vs. Cancer breakfast at the Palestra.
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A son. A pride and joy. Thank you @HaverfordSchool for investing in, loving, and nurturing our boy.
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Born the day we started the lab, our boy graduated from elementary school today. Congratulations son, you fill us with nachas and pride at the young man you are becoming.
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