Faraz K Mardakheh
@FKHM
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Associate Professor at the Department of Biochemistry, University of Oxford. Studying RNA binding proteins in cancer. https://t.co/vaShzf137C
London, England
Joined June 2009
Join me and many other scientists on BlueSky. It is really nice there! You can find me @mardakheh.bsky.social https://t.co/S1lVfNxLIe
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Happy to share our new work with @haognguyen on targeting mRNA translation of oncogenes by RNA structure remodeling with a small molecule zotatifin. Congrats to @DuyguKuzuoglu an amazing postdoc and all the authors and collaborators! https://t.co/RGH6wZqkLl
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Our post is now live! Apply and join us! https://t.co/IVjSuawnmW
I don’t post here much anymore, but this one is an important announcement for us: 🚨We are Recruiting! So come join us! 🚨#RNA #CancerResearch
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[3/5] Faraz Mardakheh received a Programme Foundation Award to uncover the mechanisms behind malignant dysregulation of ribosome biogenesis & its impact on tumorigenesis to identify novel cancer-specific therapeutic targets. @FKHM | @QMUL | @UniofOxford | #CRUKFunded
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We are looking to recruit a highly motivated postdoc with cell or molecular biology expertise. Excellent #epigenetics, #chromatin training & networking opportunities @qmulepigenetics DM me for inquiries pl apply/share https://t.co/hUEgP6fpMp
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The Barr lab @BiochemOxford has discovered the important role of cell division timing mechanisms in the formation of cancer. The research, funded by Cancer Research UK, provides valuable insight into how damaged cells are normally stopped from growing. ⬇️ https://t.co/ItD6phxfg9
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I don’t post here much anymore, but this one is an important announcement for us: 🚨We are Recruiting! So come join us! 🚨#RNA #CancerResearch
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Our latest from the indefatigable @iamjohnnyyu in collaboration with @JswLab and @kevansf. Meet GENEVA, which enables simultaneous phenotyping and profiling of cancer cell drug responses at scale; both in vitro and in vivo across a variety of models:
biorxiv.org
Many agents that show promise in preclinical cancer models lack efficacy in patients due to patient heterogeneity that is not captured in traditional assays. To address this problem, we have develo...
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Our Unit Director Prof Anne Willis has been awarded the prestigious John Barnes Prize Award from the British Toxicology Society. This prize was established in memory of the pioneering toxicologist and first Unit Director, Dr John Barnes. See more here: https://t.co/krc5PUIYnG
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@iamjohnnyyu, @nalidoust, @kevansf, and I are excited to announce a historic achievement by our team at @vevo_ai: Tahoe-100M, a 100M single-cell transcriptomic atlas, measuring how thousands of drugs impact cells from 50 diverse cancer lines. https://t.co/XT6wGV10aA
prnewswire.com
/PRNewswire/ -- Vevo Therapeutics, a biotechnology company using its Mosaic technology and next generation AI to uncover better drugs for more patients,...
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Exciting study by Amanda Andersson Rolf et al: In vitro expansion of a human fetal #pancreas #stemcell that generates all three pancreatic cell lineages”. https://t.co/mk4MdczkTM 1/
cell.com
Identification of an LGR5 as a marker for a tripotent stem/progenitor cell of the human fetal pancreas. Organoids derived from single LGR5+ cells are capable of long-term expansion in vitro and...
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Looking for #mechanobiology enthusiasts for an exciting new project - apply and spread the word! 🤩
We are looking for a: POSTDOC (M/F/D) Interested in implementing cutting-edge technologies, developing new tools, and their integration with spatial transcriptomics and mechanical measurements? Then apply 'til Dec. 31, 2024! https://t.co/N1Z7cuibaL
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Excited to share our latest work published in collaboration with Huakun Zhang’s group on how RNA structure regulates subgenomic RNA decay in wheat @BRiC_ISP @JohnInnesCentre @HaopengYu
nature.com
Nature Communications - This study shows that mRNA decay in durum wheat is affected by 3’ UTR structures and domestication-selected single-nucleotide variations, highlighting the importance...
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Promising new treatment approach for severe COVID-19! Clinical trial with Fas ligand blocker shows faster recovery & reduced mortality. Approach targets immune overreaction, potentially effective against future viruses too. #COVID19 #Science #PublicHealth
https://t.co/uPC967yxNJ
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It's our great pleasure to share our work on the role of CADASIL NOTCH3 mutations in the development of DNMT3A-related Clonal Hematopoiesis. Published now in @LeukemiaJnl Huge congrats to Raúl Sánchez-Lanzas!!! Many thanks to @LeukUK @The_MRC
https://t.co/G0dV7V5Q7P
nature.com
Leukemia - A CADASIL NOTCH3 mutation leads to clonal hematopoiesis and expansion of Dnmt3a-R878H hematopoietic clones
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Hi Science friends and followers - its time to move to Bluesky. Over the past 2 weeks the number of my followers has doubled from ~200 to ~400 with alsmot all of them scientists. We have starter packs (designated lists of who to follow e.g. by research fields).
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Grateful to UCSD for sharing our story "Key Pathway Leading to Neurodegeneration in Early Stages of ALS Identified"
today.ucsd.edu
Researchers at UC San Diego identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed...
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Looks like the science twitter mass migration to Bluesky is gaining more traction in recent days! Join us there! Together we can make science twitter great again 😁. You can find me under this handle: https://t.co/WRWDgffJby
https://t.co/S1lVfNxLIe
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Into (r)RNA modifications? Check out the new review article by @EvaMariaNovoa and me, out today in @TrendsCellBio!
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Join the Hallegger Lab in Oxford! Two post-doc positions available on how altered condensation of TDP-43 changes RNA metabolism. Biophysics of protein-RNA condensates and neuronal transcriptomics:
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