Juan Sanchez
@_Juan_C_Sanchez
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Biophysics PhD student at UW-Madison and member of Dr. Elizabeth Wright's Lab. Using #cryoEM to study prokaryotic appendages and host-phage interactions.
Madison, Wisconsin
Joined July 2020
Here's how to color a protein by the distance of its C-alpha atoms to another aligned protein using ChimeraX. Rabbit actin (1j6z) colored by similarity to an archaeal crenactin (4bql). How-to video https://t.co/N0yYkzApUf
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If you are interested in high-res #CryoET #Teamtomo #CAFR, I will be speaking at #MM2022Portland on Monday & Wednesday showing our recent results with Martin Obr on STA. Yes that is sub-2A STA from very small number of particles using #Warp & #M
https://t.co/XC6cuobyoV
Next week Ron Kelly from my team will show Cryo Auto Slice & View at #MM2022Portland from eukaryotic cells, HPF tissues and more using Plasma-FIB. See the link below. Here is #Chlamydomonas_reinhardtii sliced with Argon plasma with spectacular contrast. https://t.co/XC6cuobyoV
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A Filamentous Bacteriophage Protein Inhibits Type IV Pili To Prevent Superinfection of Pseudomonas aeruginosa
pubmed.ncbi.nlm.nih.gov
Pseudomonas aeruginosa is an opportunistic pathogen that causes infections in a variety of settings. Many P. aeruginosa isolates are infected by filamentous Pf bacteriophage integrated into the...
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Correlative cryogenic montage electron tomography for comprehensive in-situ whole-cell structural studies
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Super excited to share our lab first preprint!! Structure of human CST-pol-alpha/primase bound to telomere overhang! An amazing effort led by @UWMadBiophysics grad student @QixiangHe, lab mom, Xiuhua, @uwmadisonipib grad student @_biancachavez, and @UWBiochem undergrad Ben Lusk.
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Don’t miss next week’s seminar (11/29) by Yifan Cheng on single particle #cryoEM. A previous tweet about this talk was deleted, as information has been upated. Livestream at https://t.co/hr7q7cfo6h.
@yifan_ucsf @HHMINEWS @GrantCryoEMLab
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Mark the dates! June 7-8, 2022, we will be hosting a #Steenbock symposium for the grand opening of the @UWBiochem #cryoEM and #cryoET research centers! More details to follow, including a great line up of speakers and other event details.
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How does epistasis influence the evolution of an allosteric protein? We show that an allosteric protein simultaneously traverses multiple fitness landscapes shaped by epistasis which collectively govern the evolutionary trajectory of the protein.
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Check out the exciting #cryoEM work going on in the @erwright73 lab. Talks today and tomorrow by @Pangolininator (B04.3 #631), @jykim35 (B02.3 #929), and @Microscope_Dan (B02.4 #993) at #MM2021Virtual!
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Are you the writer you want to be? Learn from Editor-in-Chief of the Microscopy and Microanalysis journal , John Mansfield -- only at this year’s student pre-meeting congress, PMCx60 on July 31st!
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Hello fellow #microscopy enthusiasts! Did you want to attend and present at the @MicroscopySoc #MM2021Virtual meeting and didn’t submit an abstract in time? You still a few more days to upload a post-deadline poster abstract! Link: https://t.co/pOmMBOaqpl
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A new @biorxiv_cellbio #PrePrint from lab members, @Pangolininator @jykim35 & @JYang22638056 ! They developed workflows for using the @AlveoleLab #primo system for #micropatterning substrates to culture #neurons and other #cells for #CLEM and #cryoET . Awesome work!
Whole-cell cryo-electron tomography of cultured and primary eukaryotic cells on micropatterned TEM grids https://t.co/dIh9CQHQuk
#biorxiv_cellbio
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Please join us tomorrow at 2pm ET for an important conversation: "Navigating Increasing Diversity in Microscopy” (in partnership with MSA's "Lens On" Series). Register here: https://t.co/WQpNDwPOlL…YouTube link: https://t.co/0WuwQskilo
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Our paper on deep mutational scanning of the receptor binding domain of T7 is now published @eLife . We are excited about the promise of synthetic phages for antibacterial therapy. Terrific work by @phil_huss
https://t.co/mzIjVKmyDW
elifesciences.org
An unbiased mutational screen decodes the molecular basis of phage receptor interactions, identifies key functional regions determining activity and host range, and demonstrates the potential for...
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.@UWBiochem's Vatsan Raman is among the recipients of an NIH grants to support bacteriophage therapy research. Read more: https://t.co/pWcW5WhYmN
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#TeamCryo is best team!
Day 2 of #JBCMethodsMadness begins with the defending champ facing off against a tournament rookie! ROUND 1: #TeamCryo vs. #TeamMachine Who should advance to the next round? Let us know in the comments and retweet to help spread the word!
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Just registered for BLAST XVI. Should be a great meeting! https://t.co/W22l6hrPWz
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Great Q&A session held by @SciPolSam on her experience as a @BiophysicalSoc Congressional Fellow. So many great opportunities for a career in science policy. Make sure to follow her!
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There's a great @UCSDDASL panel discussion coming up at 3pm PST for anyone interested in a non-academic career path and how diversity looks in this space. #DASL #DASLSymposium #DiversityInSTEM Diversity in Non-Academic Science https://t.co/iwDUi7vlLc
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Really excited for UCSD's inaugural Diversity and Science Symposium. @JudithSimcox will be part of some great panels schedule for Wednesday and Thursday. #DiversityandInclusion #STEM Event Schedule: https://t.co/HOmCAKdTPx Registration Link: https://t.co/zFYf5Qf1Mh
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