WilsonLab
@WilsonLab2
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Ribosomes & Translation Regulation; Antibiotics & Resistance Mechanisms; Structural Biology & Cryo-EM; University of Hamburg.
Hamburg, Germany
Joined June 2018
Our latest work on structures of translation initiation complexes trapped by natural product inhibitors kasugamycin, edeine and GE81112 is out in the Biorxiv…
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RT @NatureSMB: New online! Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial….
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RT @NatureMicrobiol: Out Now! Deep learning reveals antibiotics in the archaeal proteome #DeepLearning #ArtificialI….
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RT @DjuranovicLab: Our RAPPL purification of ribosomes and associated material is finally out. I am really proud of this study in collabor….
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RT @jomaa_lab: Check out our new preprint on the discovery of a molecular switch in NAC that mediates nascent chain sorting on the ribosome….
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RT @GlattSebastian: We are excited to share our latest research on Q-modification in precursor-tRNAs, which just got published in @NatureCo….
nature.com
Nature Communications - tRNA modifications are essential for function, yet their timing relative to processing is unclear. Here, the authors show that queuosine and derivative modifications occur...
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RT @O_Borkowski: How many plasmids can bacteria carry? A synthetic biology perspective.
royalsocietypublishing.org
Plasmids are pinnacle tools in synthetic biology and other biotechnological applications. They serve as the simplest approach to introduce recombinant DNA, which is then transcribed into RNA that...
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RT @NatureMicrobiol: Out Now! Structure of an archaeal ribosome reveals a divergent active site and hibernation factor .
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Preprint from our collaboration with the labs of Gerry Wright and Shura Mankin @shuramankin identifying the first translation inhibitor binding to the E-site of the bacterial ribosome…
researchsquare.com
A significant challenge in addressing the antibiotic resistance crisis is identifying new antimicrobial compounds. Although natural products produced by fungi and bacteria, particularly actinomycet...
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RT @The_Ban_Lab: New paper out in Mol Cell, where we show how N-myristolytransferases lipidate proteins on the translating ribosome!.Contin….
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RT @maxplanckpress: Thrilled that Patrick Cramer @mpgpresident was elected a Foreign Member @royalsociety, here at today's event! 🥳Congratu….
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RT @RnaLaboratory: Mammalian tRNA acetylation determines translation efficiency and tRNA quality control
nature.com
Nature Communications - Acetylation is a posttranscriptional modification widely distributed across RNA types. Here, the authors uncover the role of tRNA ac4C12 for translational efficiency and...
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RT @DjuranovicLab: @DjuranovicLab is from today officially part of @BrownUniversity and Brown RNA center. We will have our new website soon….
rna.brown.edu
Our mission is to advance RNA science through fundamental discovery, technology development, and translational impact that accelerates life-changing health solutions.
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RT @buildmodels: Time-resolved cryo-electron microscopy can resolve protein motion on millisecond or even microsecond timescales, but the n….
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RT @KorostelevLab: With our RTI colleagues Xiaobin Ling and @WenwenFang2, we report cryo-EM structures of enigmatic bacterial RNA nanocages….
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RT @KorostelevLab: Activation of Retron-Septu for antiphage defense. Congrats @futianmin and all co-authors!.https:….
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Doudna super computer :).
DOE Announces New Supercomputer Powered by Dell and NVIDIA to Speed Scientific Discovery.
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Designing New Chimeric Proline-Rich Antimicrobial Peptides to Enhance Efficacy Toward the ESKAPE+E: Beyond Sequence Extension
mdpi.com
Proline-rich antimicrobial peptides (PrAMPs) primarily exert their antimicrobial effects intracellularly, inhibiting protein synthesis. B7-005, a synthetic 16-amino acid PrAMP, has a broader antimi...
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RT @MPI_Biochem: Congratulations! The #ShawPrize in Life Science & Medicine 2025 is awarded to Wolfgang Baumeister for his pioneering devel….
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