Chi-Min Ho
@mimi1inh
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#NewPI of the @cmholab @Columbia_MI. Using CryoEM/ET to study malarial membrane protein complexes. Co-host of #ThePlungePodcast @ https://t.co/5crCxDkeUN.
Joined May 2017
The Lander Lab is now hiring a postdoc to investigate cAMP signaling pathways in T. cruzi. Prospective candidates should be enthusiastic, proactive, and passioned about science! Use this link to apply: https://t.co/jqa6zTsHZL
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This 1998 paper is, without question, one of the most beautiful in the history of biology. It answers two questions: First, how does a potassium channel let in K+ ions while excluding Na+ ions? And second, how does it funnel 100 million of those ions through each second? These
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Want to know how lipidation of some nascent chains takes place by NMT2-- Check our latest work on how NAC couples Protein Synthesis with Nascent Polypeptide Myristoylation on the Ribosome out today @embojournal : https://t.co/YmsR18WcRJ
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Cryo-EM structure of endogenous Plasmodium falciparum Pfs230 and Pfs48/45 fertilization complex | Science
science.org
Malaria parasite fertilization occurs in the midgut of a female Anopheles mosquito. Blocking fertilization within the mosquito can prevent malaria transmission. Plasmodium falciparum Pfs230 and...
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Happy to share structures of kainate receptor channel GluK2 in complex with auxiliary subunits Neto2, which slow receptor kinetics, in apo closed and open conducting states, both with 2-fold symmetrical LBD layer! @shantigangwar @MariaKarela3 @LauraYen42
https://t.co/r4RWqXAxCn
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New online! Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial drug https://t.co/PCq38IjXjm
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Our #CryoET story on how a top antimalarial drug candidate perturbs the native malarial translation machinery is out @NatureSMB🥳 https://t.co/5SaPnwQ4zf Massive team effort led by @leonie_anton @mehsehret @Wenjing_Cheng_ in collaboration with @DziekanJerzy @CowmanAlan #teamtomo
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Out Now! HIV-1 nuclear import is selective and depends on both capsid elasticity and nuclear pore adaptability https://t.co/536wnBx4Hp
#HIVResearch #ViralScience #Microbiology
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In our latest preprint on bioRxiv, we present the in situ structure of the human gap junction at 14 Å resolution using cryo-ET. The structure provides a blueprint for investigating how connexin regulation shapes intercellular communication in health and disease.
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We have a preprint for you EHD2 forms rings on caveolae necks, in contrast to most EHDs forming helices. We determined its structure on membranes and show that N-term acts as a spacer By Elena Vazquez-Sarandeses, Vasya @v_mikirtumov Jeff Noel&Oli Daumke https://t.co/kq450wTJkV
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Check out our latest preprint with Qi lab on the structure and disease physiology of the human ERAD complex. Outstanding work by Leo, a cell physiologist whom we successfully tempted into structural biology! Preprint: https://t.co/ebaTAJdFNN
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Exciting findings from @JunLiuLab #postdoc @YueJianUSTC @YaleMed Architecture and activation of the Legionella Dot/Icm type IVB secretion machine #cryoEM #cryoET #Legionella
biorxiv.org
The Dot/Icm machine in Legionella pneumophila is one of the most versatile type IV secretion systems (T4SSs), with a remarkable capacity to translocate over 330 different effector proteins across the...
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@HypothesisFund Scout Karmella Haynes (@EmoryUniversity) is working on the cutting edge of the cutting edge. And that’s not an easy place to be. Listen to the latest episode of The Leap!
When there was no clear space for her work, synthetic biologist Karmella Haynes created her own field of research. Hear about her career and the challenges she faced while pioneering a new field in Ep. 9 of “The Leap.” By @HypothesisFund + @SciFri: https://t.co/r5hIGmQnnw
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Learning about the history and use of Expansion Microscopy with Sabrina Absalon for our morning lecture #MBLBoP2025
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Forward-looking preview by @WUBin10069342 to our latest paper @Structure_CP by @AndrewNChang highlighting the power of #AI in #cryoEM of patient-derived samples: https://t.co/dYEB4JCSpB Paper: https://t.co/PQi3OAwaiM Thanks to @pixelbaumarkt @Intein for #crYOLO, & @cryosparc
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New preprint from @DuXDaniel @FitzpatrickLab shows #femtosecond light pulses can lens electron beams, promising higher contrast in #cryoET and better aberration correction in #cryoEM
https://t.co/Ve5rDLTg4A Experiments made possible by support from @cziscience #ImagingTheFuture
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We are looking for motivated and enthusiastic research fellow to join our group to investigate on #ERC project on cell division in malaria parasite. Job Vacancy at the University of Nottingham: Research Associate/Fellow (fixed term) https://t.co/HyTLdQv5c7.
jobs.nottingham.ac.uk
Applications are invited from highly motivated and enthusiastic candidate to the above role to investigate and perform research to disseminate findings on a ERC project “Unravelling the atypical...
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📢 Call for Abstracts! Are you a PiP scientist working in parasitology? We invite you to present your research as a short talk during this exciting event.
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🎉 Join Us for Parasite Day with PiP 2025! We are thrilled to announce Parasite Day with @PiParasitology on June 27, 2025, from 9:00 am to 1:00 pm EDT! This virtual symposium will spotlight groundbreaking work in parasitology by scientists from historically excluded backgrounds.
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Dr. @kkariko's journey is a powerful example of the kind of science we support at The @HypothesisFund: bold, curiosity-driven research pursued despite the odds. ✨Listen to her incredible story in the 1st episode of The Leap - available now! 👇
Dr. @kkariko spent decades experimenting with mRNA. She was scoffed at, demoted, and eventually forced to retire. Then, she won the Nobel Prize. Listen to her story in the first episode of “The Leap,” produced with the @HypothesisFund. https://t.co/MGcFsDB9co
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