Siyuan Ding
@sding88
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Assistant Professor of Molecular Microbiology at Washington University in St. Louis. Interested in virology, gut, innate immunity, movies, and hiking
St. Louis, MO
Joined July 2017
Excited to share the first paper from our lab in 2025! Herculean effort by @gaopenghou, the paper demonstrates that UV-inactivated replication-defective rotaviruses can cause diarrhea in neonatal mice.
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Great opportunity to obtain additional funding and publicity for your work! Don't miss out!.
Applications are now being accepted for the Michelson Prizes: Next Generation Grants! . We’re seeking applicants who are deepening our understanding of human immunology and uncovering new approaches to combating diseases. All early-career investigators, postdocs, clinical
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RT @MichelsonMedRF: Applications are now being accepted for the Michelson Prizes: Next Generation Grants! . We’re seeking applicants who ar….
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Congratulations to Juhee on a stellar thesis defense! Clear, thoughtful, and thorough. Your work on rotavirus and SARS-CoV-2 reflects incredible perseverance. It's been a privilege watching you grow into an independent scientist. Wishing you all the best in your next chapter!🎓👏
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I presented part of this data at ASV2023 almost two years ago! Very happy to see it comes to fruition! Heroic effort by @GaopengHou! Close to 100 panels in main figures and over 100 panels in supplemental figures. .
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Its function is highly conserved in multiple cell types including primary human intestinal epithelial cells and hepatocytes and many vertebrate species.
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We identified SAMD9 as a common sensor of cytosolic dsDNA and dsRNA molecules and a key host restriction factor of the infection of multiple dsRNA viruses in vitro and in vivo!.
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We are hiring a highly motivated postdoctoral fellow to study the molecular biology and pathogenesis of enteric viruses that cause diarrhea in human infants. More details on the Ding Lab website - DM or email me!.
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@GaopengHou suggesting that this is a host response to clear out the virus, with new implications for infectious and non-infectious diarrhea disease. A great collaboration with @dermodylab! @WUSTLnews.
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We identified new antiviral factors that when knocked out enhance rotavirus infection. This has significant implications for viral reverse genetics optimization and live-attenuated vaccine production. Huge effort by postdoc Yinxing Zhu and great collaboration with @baldridge_lab.
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Our new CRISPR screen paper just came online: Different from the previous live/dead selection (PMID: 29662124), here we made a fluorescent reporter rotavirus and performed sorting-based screen.
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Happy to share our new manuscript out today in @PLOSPathogens Great effort by Enkai Li, a new postdoc in the lab, the paper demonstrates that rotavirus NSP1 mediates viral dissemination to extra-intestinal organs and is responsible for biliary obstruction.
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We are HIRING! Our department is looking for MORE THAN ONE Tenure Track Assistant Professors! Come be my colleagues! See detail below. Please consider applying and sharing widely! @WUSM_MolMicro @washumedicine
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Annual lab retreat is a huge success! Celebrating our 5th anniversary at TopGolf. Feeling incredibly luck to have these talented people in the lab and looking forward to them becoming future science leaders!
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The Ding Lab at the Washington University in St. Louis ( is hiring! We are looking for motivated postdocs and technicians to study rotavirus biology and vaccines using viral reverse genetics, mouse models, and human intestinal organoids. Spread the word!.
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